iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091324

UUCD1 version

UUC-PaT-01008

Ensembl Protein ID

ENSPTRP00000006324.2

UniProt Accession

H2Q3P2; H2Q3P2_PANTR

Genbank Protein ID

JAA09207.1; JAA11708.1; JAA26211.1; JAA35746.1

Protein Name

Ubiquitin-conjugating enzyme E2L 6

Genbank Nucleotide ID

GABC01002131; GABF01010437; GABD01006889; GABE01008993

Gene Name

UBE2L6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000003661.4	ENSPTRT00000006857.2	ENSPTRP00000006324.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.80e-42	142.7	6	141

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R+ kel++l+k+pp++++   +d++++  w++l+l p++ pY+ ++F+l+i+fp++YPfkPP +kf+tki+hPnv+enG++Cl i+ ++
   Q: 6    RVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLL-PDQPPYHLKAFNLRISFPPEYPFKPPMIKFTTKIYHPNVDENGQICLPII-SS 92
           899********************************.**************************************************.5* PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           e+W+p+++  +vl +++ l+++pn+++pl+ + a+ll++n+e ++k+++
   Q: 93   ENWKPCTKTCQVLEALNVLVNRPNIREPLRMDLADLLTQNPELFRKNAE 141
           **********************************************986 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MMASMRVVKE LEDLQKKPPP YLRNLSSDDA NVLVWHALLL PDQPPYHLKA FNLRISFPPE 60
YPFKPPMIKF TTKIYHPNVD ENGQICLPII SSENWKPCTK TCQVLEALNV LVNRPNIREP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGTGGGG TCCCCGGGGC GGGGCGGGGC GCGCTGTGTC GCGGGTCGGA GCTCGGTCCT 60
GCTGGAGGCC ACGGGTGCCA CACACTCGGT CCCGACATGA TGGCGAGCAT GCGAGTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0032020--P:ISG15-protein conjugation
GO:0019941--P:modification-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001818	Ailuropoda melanoleuca	71.24	2.00e-63	234.00
IUUC-Bta-012539	Bos taurus	69.93	5.00e-61	226.00
IUUC-Cja-019456	Callithrix jacchus	90.85	4.00e-80	289.00
IUUC-Cfa-021275	Canis familiaris	70.59	5.00e-63	233.00
IUUC-Cpo-022261	Cavia porcellus	66.01	1.00e-58	218.00
IUUC-Csa-023794	Chlorocebus sabaeus	90.79	5.00e-80	289.00
IUUC-Cho-024821	Choloepus hoffmanni	82.64	3.00e-68	249.00
IUUC-Dno-029632	Dasypus novemcinctus	80.39	3.00e-70	256.00
IUUC-Dor-030595	Dipodomys ordii	75.00	1.00e-48	184.00
IUUC-Eca-033746	Equus caballus	75.82	2.00e-66	244.00
IUUC-Fca-035417	Felis catus	71.90	1.00e-63	234.00
IUUC-Ggo-045537	Gorilla gorilla	98.69	2.00e-86	310.00
IUUC-Hsa-045943	Homo sapiens	100.00	2.00e-87	313.00
IUUC-Itr-048889	Ictidomys tridecemlineatus	69.93	1.00e-60	225.00
IUUC-Laf-053524	Loxodonta africana	74.51	7.00e-60	222.00
IUUC-Mcc-054818	Macaca mulatta	92.11	5.00e-81	292.00
IUUC-Meu-055936	Macropus eugenii	60.91	6.00e-35	138.00
IUUC-Mmr-060799	Microcebus murinus	87.58	2.00e-77	280.00
IUUC-Mmu-063359	Mus musculus	76.47	3.00e-66	243.00
IUUC-Mpu-066122	Mustela putorius furo	68.24	5.00e-59	219.00
IUUC-Mlu-067283	Myotis lucifugus	71.90	4.00e-60	223.00
IUUC-Nle-069829	Nomascus leucogenys	92.81	8.00e-82	295.00
IUUC-Opr-071062	Ochotona princeps	71.24	3.00e-62	229.00
IUUC-Oan-073297	Ornithorhynchus anatinus	70.37	8.00e-43	164.00
IUUC-Ocu-074709	Oryctolagus cuniculus	79.45	1.00e-65	241.00
IUUC-Oga-088256	Otolemur garnettii	84.97	5.00e-76	275.00
IUUC-Oar-089370	Ovis aries	69.18	8.00e-58	215.00
IUUC-Pan-092601	Papio anubis	91.10	2.00e-76	276.00
IUUC-Pab-098184	Pongo abelii	97.39	3.00e-85	306.00
IUUC-Pca-101080	Procavia capensis	75.69	2.00e-61	227.00
IUUC-Rno-104863	Rattus norvegicus	73.86	9.00e-66	241.00
IUUC-Sha-107162	Sarcophilus harrisii	56.86	3.00e-46	177.00
IUUC-Ssc-115506	Sus scrofa	77.78	1.00e-67	248.00
IUUC-Tsy-118811	Tarsius syrichta	70.83	1.00e-56	211.00
IUUC-Ttr-129266	Tursiops truncatus	77.12	5.00e-68	249.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence