iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107384

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01074384

Gene Name

RNF112

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013840.1	ENSSHAT00000016398.1	ENSSHAP00000016263.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	9.10e-08	32.2	30	97
E3 activity/RING/RING	5.80e-06	26.9	34	78

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk.....tcPvtrqplteedlvPnltlrrliq 66
           +++ C+I  el+rdPv l++G+ + +++I  + as         cPv+r + + + lvP + lr+l +
   Q: 30   SDLTCSICWELFRDPVSLECGHNFCAQCITCHWASRVPgsqppCCPVCRMRCDRRRLVPDTRLRSLTE 97
           5789***************************996665566788*********************9976 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iC+e f+d p++l CgH f+a+C+  +w  +    s+   CP+Cr
   Q: 34   CSICWELFRD-PVSLECGHNFCAQCItCHW-ASRVPGSQPPCCPVCR 78
           ********99.***************9899.77777899999****8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MENRNDHLSS SLPGSPSLRT SIDTLDLLTS DLTCSICWEL FRDPVSLECG HNFCAQCITC 60
HWASRVPGSQ PPCCPVCRMR CDRRRLVPDT RLRSLTENMN LLQQNAGSNQ KLYDGHSTEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGAACAGA AACTGATTGA AGACCGAAGT GAAATCCTCC ACTGTTTGCT TTCTCAGTGA 60
AGGTACATCC TTAGGCAGGT AAGTACATTC CCTTAGTCTC TGGTCTTCTT TCTCCTCGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR030386--G_GB1_RHD3_dom
IPR015894--Guanylate-bd_N
IPR027417--P-loop_NTPase
IPR003613--Ubox_domain
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51715--G_GB1_RHD3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02263--GBP
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071158--P:positive regulation of cell cycle arrest
GO:0045687--P:positive regulation of glial cell differentiation
GO:0045666--P:positive regulation of neuron differentiation

KEGG

shr:100920104

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004447	Anolis carolinensis	40.24	2.00e-102	366.00
IUUC-Cel-018342	Caenorhabditis elegans	28.85	8.00e-10	56.20
IUUC-Lch-049938	Latimeria chalumnae	34.53	3.00e-59	222.00
IUUC-Meu-056771	Macropus eugenii	69.64	0.00e+00	715.00
IUUC-Mdo-062283	Monodelphis domestica	64.60	0.00e+00	668.00
IUUC-Oan-073033	Ornithorhynchus anatinus	43.94	6.00e-108	384.00
IUUC-Ppa-095862	Physcomitrella patens	42.11	2.00e-06	45.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence