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Tag Content
UUCD2 ID IUUC-Oga-088684
UUCD1 version UUC-OtG-00447
Ensembl Protein ID ENSOGAP00000009882.2
UniProt Accession H0X3Z1; H0X3Z1_OTOGA
Genbank Protein ID ENSOGAP00000009882
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAQR03003095
Gene Name HACE1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000011034.2 ENSOGAT00000011043.2 ENSOGAP00000009882.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 3.70e-119 398.0 576 906
Active Site
Position(s) Description Evidence
877 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           ++lk+ + v+f gEeg+++ Gv re+++ ls+e+ npd+ lf++s++  +t+qpn++s++ np+hl++F+f+G++lg+al +++l+++ 
   Q: 576  AKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIVNPDYALFTQSADVGTTFQPNSNSYV-NPDHLNYFRFAGQILGLALNHRQLVNIY 662
           679999*************.***************************************9.89************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           +++sfyk++lg +++++d++++dpe++k+l++i++n   di++lgl+ltfsv+++++g ++e+ LkpgG +i Vt++Nk eYv+lv+e+
   Q: 663  FTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDN---DISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTEL 748
           **********************************99...************************************************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+++ i+ q++af +Gf+  ip++l++lF+e elell++G++eidv+d+ k+t+y++gy++++p+iqwFwev+e++++eer  +LqFvT
   Q: 749  RMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVT 837
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           gssr+P+gGfa+++     + f+i     +++ lP+s+TC+n+LkLPeY+skeilk++Ll+A + +  g
   Q: 838  GSSRVPHGGFANIMggsgLQNFTIAAvPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGsYG 906
           ******************8888888868888********************************986555 PP
   
Organism Otolemur garnettii
Protein Sequence
(Fasta)
MERAMEQLNR LTRSLRRART VELPEDNETA VYTLMPMVMA DQHRSVSELL SNSKFDVNYA 60
FGRVKRSLLH IAANCGSVEC LVLLLKKGAN PNYQDISGCT PLHLAARNGQ KKCMSKLLEY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-088684|E3,HECT|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCTGCCCTT TCGCCCGCTG GACGGGCCCG GGCGGGATGT AGGGCGCTGG GCGCTGAGGC 60
CGCCGCGGCG GCGAGGGGAG CGCGGAGGGC GCCCCGAGGA TGGAGAGAGC GATGGAGCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-088684|E3,HECT|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000569--HECT_dom
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50237--HECT
Pfam

PF12796--Ank_2
PF00632--HECT
PRINTS

PR01415--ANKYRIN
SMART

SM00248--ANK
SM00119--HECTc
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0000139--C:Golgi membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030334--P:regulation of cell migration
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001490 Ailuropoda melanoleuca 98.68 0.00e+00 1878.00
IUUC-Apl-003400 Anas platyrhynchos 88.21 0.00e+00 1152.00
IUUC-Aca-005375 Anolis carolinensis 91.44 0.00e+00 1735.00
IUUC-Ame-011847 Astyanax mexicanus 84.78 0.00e+00 1642.00
IUUC-Bta-012831 Bos taurus 98.20 0.00e+00 1825.00
IUUC-Cja-019160 Callithrix jacchus 99.23 0.00e+00 1891.00
IUUC-Cfa-020346 Canis familiaris 98.68 0.00e+00 1875.00
IUUC-Cpo-021766 Cavia porcellus 97.58 0.00e+00 1857.00
IUUC-Csa-023768 Chlorocebus sabaeus 98.79 0.00e+00 1880.00
IUUC-Cho-024688 Choloepus hoffmanni 94.53 0.00e+00 1180.00
IUUC-Cin-025417 Ciona intestinalis 43.40 0.00e+00 701.00
IUUC-Csv-025993 Ciona savignyi 43.81 0.00e+00 751.00
IUUC-Dre-027819 Danio rerio 85.54 0.00e+00 1630.00
IUUC-Dno-029027 Dasypus novemcinctus 98.25 0.00e+00 1864.00
IUUC-Dor-030327 Dipodomys ordii 91.06 0.00e+00 1642.00
IUUC-Ete-032966 Echinops telfairi 90.89 0.00e+00 1707.00
IUUC-Eca-034339 Equus caballus 98.68 0.00e+00 1874.00
IUUC-Eeu-034544 Erinaceus europaeus 70.11 0.00e+00 694.00
IUUC-Fca-035617 Felis catus 98.61 0.00e+00 1338.00
IUUC-Fal-036687 Ficedula albicollis 91.20 0.00e+00 1758.00
IUUC-Gmo-039508 Gadus morhua 87.95 0.00e+00 827.00
IUUC-Gga-040845 Gallus gallus 91.52 0.00e+00 1781.00
IUUC-Gac-041894 Gasterosteus aculeatus 85.14 0.00e+00 1585.00
IUUC-Ggo-044465 Gorilla gorilla 95.18 0.00e+00 1808.00
IUUC-Hsa-045731 Homo sapiens 98.90 0.00e+00 1882.00
IUUC-Itr-048716 Ictidomys tridecemlineatus 99.01 0.00e+00 1875.00
IUUC-Lch-050436 Latimeria chalumnae 89.74 0.00e+00 1692.00
IUUC-Loc-052287 Lepisosteus oculatus 84.99 0.00e+00 1664.00
IUUC-Laf-053846 Loxodonta africana 98.79 0.00e+00 1873.00
IUUC-Mcc-055845 Macaca mulatta 98.90 0.00e+00 1882.00
IUUC-Meu-056060 Macropus eugenii 98.27 0.00e+00 707.00
IUUC-Mga-059935 Meleagris gallopavo 94.01 0.00e+00 1759.00
IUUC-Mmr-060960 Microcebus murinus 99.56 0.00e+00 1891.00
IUUC-Mdo-061851 Monodelphis domestica 93.53 0.00e+00 1822.00
IUUC-Mmu-063657 Mus musculus 97.25 0.00e+00 1857.00
IUUC-Mpu-066161 Mustela putorius furo 99.25 0.00e+00 828.00
IUUC-Mlu-067354 Myotis lucifugus 96.69 0.00e+00 1803.00
IUUC-Nle-069112 Nomascus leucogenys 98.79 0.00e+00 1879.00
IUUC-Opr-070686 Ochotona princeps 89.32 0.00e+00 811.00
IUUC-Ont-072398 Oreochromis niloticus 84.87 0.00e+00 1583.00
IUUC-Oan-073194 Ornithorhynchus anatinus 95.32 0.00e+00 1739.00
IUUC-Ocu-074397 Oryctolagus cuniculus 86.34 0.00e+00 1577.00
IUUC-Ola-086777 Oryzias latipes 81.05 0.00e+00 1566.00
IUUC-Oar-089428 Ovis aries 97.88 0.00e+00 1831.00
IUUC-Ptr-090529 Pan troglodytes 98.79 0.00e+00 1880.00
IUUC-Pan-091702 Papio anubis 99.01 0.00e+00 1883.00
IUUC-Psi-093969 Pelodiscus sinensis 91.20 0.00e+00 1708.00
IUUC-Pfo-097364 Poecilia formosa 86.20 0.00e+00 1611.00
IUUC-Pab-098574 Pongo abelii 98.90 0.00e+00 1882.00
IUUC-Pca-100525 Procavia capensis 86.87 3.00e-179 622.00
IUUC-Pva-102365 Pteropus vampyrus 87.03 0.00e+00 1603.00
IUUC-Rno-105153 Rattus norvegicus 96.92 0.00e+00 1853.00
IUUC-Sha-107319 Sarcophilus harrisii 93.43 0.00e+00 1815.00
IUUC-Sar-113449 Sorex araneus 81.87 7.00e-178 617.00
IUUC-Ssc-115865 Sus scrofa 98.57 0.00e+00 1873.00
IUUC-Tgu-117225 Taeniopygia guttata 91.20 0.00e+00 1774.00
IUUC-Tru-118026 Takifugu rubripes 82.40 0.00e+00 1562.00
IUUC-Tsy-119407 Tarsius syrichta 85.93 0.00e+00 1579.00
IUUC-Tni-120234 Tetraodon nigroviridis 83.97 0.00e+00 1273.00
IUUC-Tur-126774 Triticum urartu 28.92 2.00e-46 181.00
IUUC-Tbe-127708 Tupaia belangeri 88.87 0.00e+00 884.00
IUUC-Ttr-128667 Tursiops truncatus 98.57 0.00e+00 1874.00
IUUC-Vpa-130200 Vicugna pacos 98.53 0.00e+00 1816.00
IUUC-Xtr-132176 Xenopus tropicalis 87.51 0.00e+00 1701.00
Created Date 25-Jun-2017

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