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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106189
UUCD1 version UUC-SaC-00220
Ensembl Protein ID YDL156W
UniProt Accession Q12510; D6VRJ4; CMR1_YEAST
Genbank Protein ID CAA66335.1; CAA98730.1; DAA11704.1
Protein Name DNA damage-binding protein CMR1; Changed mutation rate protein 1
Genbank Nucleotide ID X97751; Z74204; BK006938
Gene Name CMR1; YDL156W; D1536
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YDL156W YDL156W YDL156W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMUniProtBioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.90e-13 48.6 348 366
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 15   llvsGsdDgtikvWDlrtg 33
            +++Gs D t+k+WD+r  
   Q: 348  EIATGSLDRTLKIWDTRNL 366
           49*************9865 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA in vitro (PubMed:22367945). May be involved in DNA-metabolic processes (PubMed:23349438).
 DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA in vitro (PubMed:22367945). May be involved in DNA-metabolic processes (PubMed:23349438).
Protein Sequence
(Fasta)
MPELTEFQKK RLENIKRNND LLKKLHLSGV ASQIKHEAGV LEKSRAPAKK KQKTTNTRAT 60
KSASPTLPTR RSRRLRGESA DDVKGIPNVN DNQLLKMGSP DGQDKNFIDA IKEKPVIGDV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106189|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGCCGGAAT TAACAGAATT TCAGAAAAAA CGTTTAGAGA ACATCAAAAG GAATAACGAT 60
TTATTGAAAA AACTCCATTT GTCTGGAGTA GCATCTCAAA TTAAGCACGA GGCTGGGGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106189|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR033052--Cmr1/WDR76
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0000790--C:nuclear chromatin
GO:0034399--C:nuclear periphery
GO:0003677--F:DNA binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:2000001--P:regulation of DNA damage checkpoint
KEGG sce:YDL156W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Atr-002605 Amborella trichopoda 24.68 8.00e-16 76.30
IUUC-Apl-003441 Anas platyrhynchos 22.73 8.00e-22 96.30
IUUC-Aca-004241 Anolis carolinensis 26.98 1.00e-26 112.00
IUUC-Aly-005444 Arabidopsis lyrata 25.23 3.00e-28 117.00
IUUC-Ath-007550 Arabidopsis thaliana 24.65 4.00e-27 114.00
IUUC-Ago-007715 Ashbya gossypii 56.48 3.00e-160 556.00
IUUC-Acl-008370 Aspergillus clavatus 31.68 8.00e-60 222.00
IUUC-Afl-008586 Aspergillus flavus 34.70 2.00e-55 208.00
IUUC-Afu-008907 Aspergillus fumigatus 31.78 5.00e-59 219.00
IUUC-Ani-009415 Aspergillus nidulans 34.78 2.00e-55 207.00
IUUC-Ang-009597 Aspergillus niger 27.31 1.00e-17 82.40
IUUC-Aor-010197 Aspergillus oryzae 34.70 1.00e-55 209.00
IUUC-Ate-010280 Aspergillus terreus 35.69 1.00e-57 215.00
IUUC-Bgr-012236 Blumeria graminis 33.70 2.00e-63 234.00
IUUC-Bta-013059 Bos taurus 24.06 2.00e-27 115.00
IUUC-Bci-013796 Botrytis cinerea 32.90 6.00e-63 233.00
IUUC-Bdi-015040 Brachypodium distachyon 25.75 6.00e-17 80.10
IUUC-Bol-015934 Brassica oleracea 24.62 5.00e-19 86.70
IUUC-Bra-018032 Brassica rapa 24.82 8.00e-21 93.20
IUUC-Cja-019043 Callithrix jacchus 24.53 1.00e-23 102.00
IUUC-Cfa-021103 Canis familiaris 25.38 2.00e-25 108.00
IUUC-Cpo-021508 Cavia porcellus 23.42 3.00e-24 104.00
IUUC-Cre-022967 Chlamydomonas reinhardtii 23.78 1.00e-08 53.10
IUUC-Csa-023555 Chlorocebus sabaeus 24.20 1.00e-22 99.00
IUUC-Cho-024931 Choloepus hoffmanni 24.76 4.00e-07 47.80
IUUC-Cin-025651 Ciona intestinalis 25.29 3.00e-25 107.00
IUUC-Cgl-026604 Colletotrichum gloeosporioides 36.69 3.00e-56 210.00
IUUC-Cne-027093 Cryptococcus neoformans 26.39 2.00e-32 131.00
IUUC-Cme-027238 Cyanidioschyzon merolae 21.47 2.00e-18 85.10
IUUC-Dre-027441 Danio rerio 25.38 2.00e-28 118.00
IUUC-Dno-029575 Dasypus novemcinctus 25.56 7.00e-28 116.00
IUUC-Dor-030554 Dipodomys ordii 26.79 5.00e-27 113.00
IUUC-Dse-031299 Dothistroma septosporum 35.33 2.00e-57 214.00
IUUC-Ete-032716 Echinops telfairi 26.16 4.00e-14 70.90
IUUC-Eca-034027 Equus caballus 23.73 4.00e-13 67.40
IUUC-Eeu-035234 Erinaceus europaeus 29.01 5.00e-13 67.40
IUUC-Fca-035892 Felis catus 28.28 9.00e-25 106.00
IUUC-Fal-036986 Ficedula albicollis 24.94 3.00e-18 84.30
IUUC-Fox-037750 Fusarium oxysporum 31.53 8.00e-63 232.00
IUUC-Fso-038198 Fusarium solani 30.85 5.00e-50 190.00
IUUC-Gmo-039683 Gadus morhua 21.24 1.00e-07 48.90
IUUC-Gga-040479 Gallus gallus 24.92 9.00e-16 75.90
IUUC-Gac-042043 Gasterosteus aculeatus 23.28 2.00e-24 104.00
IUUC-Gma-043913 Glycine max 24.28 1.00e-31 128.00
IUUC-Ggo-045290 Gorilla gorilla 24.58 5.00e-23 100.00
IUUC-Hsa-047021 Homo sapiens 24.58 1.00e-23 102.00
IUUC-Hvu-047193 Hordeum vulgare 30.03 6.00e-23 99.80
IUUC-Itr-047914 Ictidomys tridecemlineatus 24.44 2.00e-26 112.00
IUUC-Kpa-049275 Komagataella pastoris 33.51 5.00e-78 283.00
IUUC-Lch-049718 Latimeria chalumnae 23.64 8.00e-26 110.00
IUUC-Lpe-051708 Leersia perrieri 28.21 1.00e-17 82.40
IUUC-Loc-052565 Lepisosteus oculatus 24.53 9.00e-26 109.00
IUUC-Lma-053276 Leptosphaeria maculans 30.94 2.00e-59 222.00
IUUC-Laf-053970 Loxodonta africana 25.70 8.00e-30 123.00
IUUC-Mcc-054740 Macaca mulatta 23.87 4.00e-23 100.00
IUUC-Meu-056546 Macropus eugenii 23.44 2.00e-11 62.40
IUUC-Mtr-058451 Medicago truncatula 26.00 2.00e-35 141.00
IUUC-Mla-058906 Melampsora laricipopulina 27.81 3.00e-34 137.00
IUUC-Mga-059328 Meleagris gallopavo 26.57 2.00e-21 94.70
IUUC-Mvi-060555 Microbotryum violaceum 25.55 2.00e-28 118.00
IUUC-Mmr-061520 Microcebus murinus 26.03 2.00e-30 125.00
IUUC-Mdo-062812 Monodelphis domestica 25.48 3.00e-32 131.00
IUUC-Mmu-064011 Mus musculus 25.51 2.00e-20 91.70
IUUC-Mac-065376 Musa acuminata 25.70 9.00e-09 52.40
IUUC-Mpu-066486 Mustela putorius furo 25.62 4.00e-27 114.00
IUUC-Mlu-067721 Myotis lucifugus 24.42 1.00e-14 72.40
IUUC-Nfi-068314 Neosartorya fischeri 31.43 2.00e-59 221.00
IUUC-Ncr-068896 Neurospora crassa 30.15 9.00e-54 202.00
IUUC-Nle-069369 Nomascus leucogenys 24.00 3.00e-25 107.00
IUUC-Opr-070975 Ochotona princeps 26.54 2.00e-30 125.00
IUUC-Ont-072528 Oreochromis niloticus 24.33 7.00e-25 106.00
IUUC-Oan-072955 Ornithorhynchus anatinus 23.71 2.00e-24 105.00
IUUC-Ocu-074561 Oryctolagus cuniculus 25.67 9.00e-21 93.20
IUUC-Oba-074982 Oryza barthii 28.86 7.00e-24 103.00
IUUC-Obr-076551 Oryza brachyantha 28.45 5.00e-17 79.30
IUUC-Ogl-077685 Oryza glaberrima 28.81 5.00e-25 106.00
IUUC-Ogu-078331 Oryza glumaepatula 28.81 5.00e-25 106.00
IUUC-Oin-079507 Oryza indica 28.30 6.00e-24 103.00
IUUC-Olo-080604 Oryza longistaminata 29.58 8.00e-20 89.40
IUUC-Ome-081816 Oryza meridionalis 28.81 4.00e-24 103.00
IUUC-Oni-082051 Oryza nivara 28.81 4.00e-25 107.00
IUUC-Opu-083372 Oryza punctata 28.13 2.00e-23 101.00
IUUC-Oru-084578 Oryza rufipogon 28.81 5.00e-25 106.00
IUUC-Osa-086177 Oryza sativa 28.81 5.00e-25 106.00
IUUC-Ola-087208 Oryzias latipes 24.91 1.00e-22 98.60
IUUC-Olu-087680 Ostreococcus lucimarinus 23.56 3.00e-22 97.80
IUUC-Oga-088104 Otolemur garnettii 25.94 2.00e-25 108.00
IUUC-Oar-090157 Ovis aries 25.09 1.00e-28 119.00
IUUC-Ptr-091615 Pan troglodytes 24.39 5.00e-24 103.00
IUUC-Pan-092212 Papio anubis 24.20 5.00e-23 100.00
IUUC-Psi-092950 Pelodiscus sinensis 26.67 3.00e-25 107.00
IUUC-Pma-094625 Petromyzon marinus 26.06 2.00e-10 57.80
IUUC-Pno-094824 Phaeosphaeria nodorum 32.59 8.00e-66 242.00
IUUC-Pfo-096922 Poecilia formosa 25.58 6.00e-30 123.00
IUUC-Pab-097591 Pongo abelii 24.77 1.00e-24 106.00
IUUC-Pop-099337 Populus trichocarpa 26.12 1.00e-31 128.00
IUUC-Pca-101025 Procavia capensis 24.05 2.00e-24 105.00
IUUC-Ppe-101256 Prunus persica 24.20 7.00e-20 90.10
IUUC-Pva-102453 Pteropus vampyrus 26.47 1.00e-25 109.00
IUUC-Pgr-103436 Puccinia graminis 26.09 7.00e-38 149.00
IUUC-Ptt-103899 Puccinia triticina 32.17 2.00e-35 141.00
IUUC-Pte-104258 Pyrenophora teres 30.40 3.00e-57 214.00
IUUC-Pyt-104625 Pyrenophora triticirepentis 30.43 1.00e-57 215.00
IUUC-Rno-104843 Rattus norvegicus 22.43 3.00e-20 91.30
IUUC-Sha-106672 Sarcophilus harrisii 26.57 8.00e-36 142.00
IUUC-Smo-109660 Selaginella moellendorffii 27.27 4.00e-25 106.00
IUUC-Sit-109704 Setaria italica 29.44 1.00e-29 122.00
IUUC-Sly-111853 Solanum lycopersicum 23.36 5.00e-16 77.00
IUUC-Stu-112482 Solanum tuberosum 22.16 2.00e-12 65.10
IUUC-Sbi-114517 Sorghum bicolor 29.09 6.00e-20 90.10
IUUC-Sre-114960 Sporisorium reilianum 26.67 7.00e-18 83.60
IUUC-Ssc-115568 Sus scrofa 24.81 6.00e-26 110.00
IUUC-Tgu-117276 Taeniopygia guttata 22.59 1.00e-14 72.40
IUUC-Tru-117559 Takifugu rubripes 32.58 7.00e-11 57.00
IUUC-Tsy-119027 Tarsius syrichta 24.09 6.00e-09 53.10
IUUC-Tni-120358 Tetraodon nigroviridis 25.19 5.00e-32 130.00
IUUC-Tca-121273 Theobroma cacao 25.79 3.00e-21 94.40
IUUC-Tre-121932 Trichoderma reesei 37.54 3.00e-58 217.00
IUUC-Tvi-122567 Trichoderma virens 33.08 3.00e-64 237.00
IUUC-Tae-123506 Triticum aestivum 28.25 9.00e-22 95.90
IUUC-Tme-126958 Tuber melanosporum 35.94 3.00e-40 157.00
IUUC-Tbe-127425 Tupaia belangeri 27.25 3.00e-24 104.00
IUUC-Ttr-129123 Tursiops truncatus 26.86 7.00e-23 100.00
IUUC-Uma-129495 Ustilago maydis 23.31 4.00e-19 87.80
IUUC-Vda-129981 Verticillium dahliae 30.63 1.00e-61 228.00
IUUC-Vpa-130437 Vicugna pacos 26.47 2.00e-25 108.00
IUUC-Vvi-131430 Vitis vinifera 24.86 1.00e-19 88.60
IUUC-Xtr-132670 Xenopus tropicalis 24.86 7.00e-25 106.00
IUUC-Xma-133375 Xiphophorus maculatus 29.73 4.00e-28 117.00
IUUC-Yli-134341 Yarrowia lipolytica 34.32 2.00e-70 258.00
IUUC-Zma-135413 Zea mays 28.97 8.00e-29 119.00
Created Date 25-Jun-2017

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