iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062095

UUCD1 version

UUC-MoD-00018

Ensembl Protein ID

ENSMODP00000000306.3

UniProt Accession

H9H5V2; H9H5V2_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000252.3	ENSMODT00000000310.3	ENSMODP00000000306.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.40e-19	70.3	36	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.00e-07	29.7	136	164

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    Dvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           Dv+l+ + g+ f+ah++vLaa+S++F+a+f ++l+es+  ++v +++v p+ ++ ll+++Ytg++ 
   Q: 36   DVTLEAAgGRDFPAHRAVLAAASPYFRAMFAGQLRESR-AERVRLHGVPPDMLQLLLDYSYTGRVA 100
           9*****99******************************.************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
            Ncl++ +fA++++c  L+ aa++fil+h
   Q: 136  ANCLDMQDFAEAFSCAGLAGAAQRFILRH 164
           6***************************9 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MEKPAPSAVL PFSDPAHALS LLRGLSQLRA ERKFLDVTLE AAGGRDFPAH RAVLAAASPY 60
FRAMFAGQLR ESRAERVRLH GVPPDMLQLL LDYSYTGRVA VSGDNAEPLL RAADLLQFPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAAGC CGGCGCCCTC GGCTGTGTTG CCCTTCTCGG ACCCGGCACA CGCCCTGAGT 60
CTGCTCCGGG GGCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	84.00	0.00e+00	734.00
IUUC-Apl-003189	Anas platyrhynchos	87.63	1.00e-105	375.00
IUUC-Ani-009467	Aspergillus nidulans	34.12	2.00e-07	49.30
IUUC-Ame-011774	Astyanax mexicanus	66.67	4.00e-138	484.00
IUUC-Bta-012367	Bos taurus	94.86	0.00e+00	958.00
IUUC-Cja-019501	Callithrix jacchus	87.28	0.00e+00	850.00
IUUC-Cfa-020550	Canis familiaris	94.86	0.00e+00	958.00
IUUC-Cpo-022072	Cavia porcellus	95.26	0.00e+00	947.00
IUUC-Csa-023364	Chlorocebus sabaeus	94.81	0.00e+00	844.00
IUUC-Cin-025253	Ciona intestinalis	41.33	1.00e-122	433.00
IUUC-Csv-025871	Ciona savignyi	43.35	6.00e-130	457.00
IUUC-Dre-028694	Danio rerio	72.35	0.00e+00	760.00
IUUC-Dno-029082	Dasypus novemcinctus	92.65	0.00e+00	775.00
IUUC-Dor-030680	Dipodomys ordii	94.86	0.00e+00	954.00
IUUC-Dse-031490	Dothistroma septosporum	28.05	3.00e-05	42.00
IUUC-Ete-032315	Echinops telfairi	94.22	0.00e+00	784.00
IUUC-Eca-033570	Equus caballus	90.77	1.00e-145	509.00
IUUC-Eeu-035067	Erinaceus europaeus	97.62	2.00e-104	373.00
IUUC-Fal-037103	Ficedula albicollis	84.01	0.00e+00	773.00
IUUC-Gmo-039420	Gadus morhua	68.82	0.00e+00	726.00
IUUC-Ggr-039811	Gaeumannomyces graminis	36.99	7.00e-08	51.60
IUUC-Gga-040161	Gallus gallus	83.84	0.00e+00	744.00
IUUC-Gac-041755	Gasterosteus aculeatus	70.59	0.00e+00	746.00
IUUC-Ggo-044899	Gorilla gorilla	94.66	0.00e+00	957.00
IUUC-Hsa-045834	Homo sapiens	94.66	0.00e+00	957.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	95.26	0.00e+00	961.00
IUUC-Kpa-049264	Komagataella pastoris	26.53	3.50e+00	27.70
IUUC-Lch-050338	Latimeria chalumnae	69.55	0.00e+00	752.00
IUUC-Loc-051780	Lepisosteus oculatus	74.71	0.00e+00	769.00
IUUC-Laf-053725	Loxodonta africana	94.82	7.00e-180	623.00
IUUC-Mcc-055032	Macaca mulatta	95.20	0.00e+00	948.00
IUUC-Meu-056661	Macropus eugenii	94.38	0.00e+00	639.00
IUUC-Mpo-057626	Magnaporthe poae	30.83	6.00e-07	48.90
IUUC-Mga-059821	Meleagris gallopavo	89.16	3.00e-90	324.00
IUUC-Mmu-063138	Mus musculus	95.26	0.00e+00	961.00
IUUC-Mpu-066386	Mustela putorius furo	91.34	7.00e-130	456.00
IUUC-Mlu-067807	Myotis lucifugus	92.42	5.00e-150	523.00
IUUC-Nle-069181	Nomascus leucogenys	93.68	0.00e+00	940.00
IUUC-Opr-070658	Ochotona princeps	94.27	0.00e+00	979.00
IUUC-Ont-072209	Oreochromis niloticus	70.39	0.00e+00	745.00
IUUC-Ocu-074631	Oryctolagus cuniculus	82.75	0.00e+00	804.00
IUUC-Ola-087553	Oryzias latipes	68.63	0.00e+00	726.00
IUUC-Oga-088782	Otolemur garnettii	95.26	0.00e+00	962.00
IUUC-Oar-089634	Ovis aries	94.27	0.00e+00	952.00
IUUC-Ptr-091259	Pan troglodytes	93.52	0.00e+00	668.00
IUUC-Pan-091734	Papio anubis	94.86	0.00e+00	959.00
IUUC-Psi-092979	Pelodiscus sinensis	82.79	0.00e+00	795.00
IUUC-Pma-094459	Petromyzon marinus	54.19	3.00e-126	445.00
IUUC-Pno-094945	Phaeosphaeria nodorum	34.85	3.00e-06	45.10
IUUC-Pfo-097446	Poecilia formosa	70.39	0.00e+00	746.00
IUUC-Pab-098765	Pongo abelii	94.86	0.00e+00	957.00
IUUC-Pca-101018	Procavia capensis	97.69	4.00e-92	332.00
IUUC-Pva-102730	Pteropus vampyrus	90.32	0.00e+00	903.00
IUUC-Rno-104972	Rattus norvegicus	95.06	0.00e+00	962.00
IUUC-Ssc-115869	Sus scrofa	94.63	0.00e+00	947.00
IUUC-Tgu-116562	Taeniopygia guttata	83.84	0.00e+00	802.00
IUUC-Tru-118490	Takifugu rubripes	69.41	0.00e+00	739.00
IUUC-Tni-119898	Tetraodon nigroviridis	68.60	0.00e+00	710.00
IUUC-Ttr-128976	Tursiops truncatus	96.51	1.00e-89	324.00
IUUC-Xtr-132876	Xenopus tropicalis	72.62	0.00e+00	776.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence