iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045069

UUCD1 version

UUC-GoG-01110

Ensembl Protein ID

ENSGGOP00000028727.1

UniProt Accession

G3SKT4; G3SKT4_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000034943.1	ENSGGOT00000041046.1	ENSGGOP00000028727.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-65	221.3	21	414

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 44   epkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaee 132
            +   +  +lq+lf++l+  +++a s+++l+++++++++e  +++q+D+qE+ ++l+++le++l                         
   Q: 21   AKVRIIPLQLQRLFAQLLLLDQEAASTTDLTDSFGWTSNE--EMRQHDVQELNRILFSALETSL------------------------- 82
           44556789******************************98..**********************......................... PP
   S: 133  kkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekk 220
              +++++li++l++g++ +qi+c+ec+nvs+r+e+fldl+++v++ +      l+d+L +++++ee ++++n y+c +c+++++a k+
   Q: 83   -VGTSGHDLINRLYHGTIVNQIVCKECKNVSERQEDFLDLTVAVKNVS-----GLEDALwNMYVEEEVFDCDNLYHCGTCDRLVKAAKS 165
           .789********************************************.....9*********************************** PP
   S: 221  lklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn........ 301
            kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+pfc+++e ++  +++Y+L++v++H+G++ +GHY++y+k+        
   Q: 166  AKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKPFCEQSELDDL-EYTYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwq 253
           ***********************************************999987.9********************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 254  fqeekskpdvnlkdlqseeeidhplmilkailleennlipvdqlgqkllkkigiswnkkyrkqhgplrkflqlhsqifllssdestvrl 342
           ***************************************************************************************** PP
   S: 302  ...............................ekgk.....WllfdDskVtevkeeevleetg..staYvlfYkr 337
                                          +  +     W+ ++DskV++++e++++++ +  ++aY+lfY++
   Q: 343  lknsslqaesdfqrndqqifkmlppespglnN--SiscphWFDINDSKVQPIREKDIEQQFQgkESAYMLFYRK 414
           ********999999999999999888887651..234567*******************9889*********98 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

TLFSLGPEEL GLFEDKDKPD AKVRIIPLQL QRLFAQLLLL DQEAASTTDL TDSFGWTSNE 60
EMRQHDVQEL NRILFSALET SLVGTSGHDL INRLYHGTIV NQIVCKECKN VSERQEDFLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTATTTT CTCTTGGCCC AGAAGAGCTT GGTTTGTTTG AAGATAAGGA TAAACCCGAT 60
GCAAAGGTAT TACATCTGTG ATTTACTGAG GTGTTTTAGC GTATTCAGAA AATTTTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	83.14	0.00e+00	1799.00
IUUC-Apl-004105	Anas platyrhynchos	62.75	0.00e+00	1417.00
IUUC-Aca-004715	Anolis carolinensis	61.27	0.00e+00	1367.00
IUUC-Ame-011073	Astyanax mexicanus	47.23	0.00e+00	951.00
IUUC-Bta-012487	Bos taurus	81.76	0.00e+00	1857.00
IUUC-Cja-018937	Callithrix jacchus	93.52	0.00e+00	2154.00
IUUC-Cfa-020645	Canis familiaris	78.59	0.00e+00	1237.00
IUUC-Cpo-022160	Cavia porcellus	78.35	0.00e+00	1793.00
IUUC-Csa-023078	Chlorocebus sabaeus	94.28	0.00e+00	2221.00
IUUC-Cho-025013	Choloepus hoffmanni	64.62	0.00e+00	802.00
IUUC-Csv-026193	Ciona savignyi	58.28	6.00e-41	160.00
IUUC-Dre-027416	Danio rerio	47.48	0.00e+00	1039.00
IUUC-Dno-029639	Dasypus novemcinctus	79.52	0.00e+00	1649.00
IUUC-Dor-030624	Dipodomys ordii	91.33	3.00e-155	543.00
IUUC-Ete-032626	Echinops telfairi	62.37	0.00e+00	722.00
IUUC-Eca-034208	Equus caballus	84.36	0.00e+00	1957.00
IUUC-Eeu-035340	Erinaceus europaeus	46.59	1.00e-94	341.00
IUUC-Fca-035886	Felis catus	71.87	0.00e+00	746.00
IUUC-Fal-036925	Ficedula albicollis	62.36	0.00e+00	1313.00
IUUC-Gmo-038597	Gadus morhua	44.49	0.00e+00	832.00
IUUC-Gga-041171	Gallus gallus	62.52	0.00e+00	1400.00
IUUC-Gac-041362	Gasterosteus aculeatus	44.45	0.00e+00	879.00
IUUC-Hsa-046715	Homo sapiens	97.18	0.00e+00	2256.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	80.51	0.00e+00	1810.00
IUUC-Lch-050182	Latimeria chalumnae	51.43	0.00e+00	1060.00
IUUC-Loc-052705	Lepisosteus oculatus	53.04	0.00e+00	1153.00
IUUC-Laf-054132	Loxodonta africana	79.95	0.00e+00	1863.00
IUUC-Mcc-055734	Macaca mulatta	94.70	0.00e+00	2231.00
IUUC-Meu-056135	Macropus eugenii	86.70	6.00e-115	409.00
IUUC-Mga-060092	Meleagris gallopavo	62.44	0.00e+00	1386.00
IUUC-Mmr-061546	Microcebus murinus	85.52	0.00e+00	1986.00
IUUC-Mdo-061935	Monodelphis domestica	61.12	0.00e+00	1393.00
IUUC-Mmu-063630	Mus musculus	78.07	0.00e+00	1798.00
IUUC-Mpu-066579	Mustela putorius furo	79.18	0.00e+00	1874.00
IUUC-Mlu-068034	Myotis lucifugus	82.71	0.00e+00	1881.00
IUUC-Nle-069082	Nomascus leucogenys	95.65	0.00e+00	1991.00
IUUC-Opr-070953	Ochotona princeps	72.32	0.00e+00	988.00
IUUC-Ont-072435	Oreochromis niloticus	46.09	0.00e+00	984.00
IUUC-Oan-073339	Ornithorhynchus anatinus	65.58	0.00e+00	1429.00
IUUC-Ocu-073760	Oryctolagus cuniculus	80.27	0.00e+00	1892.00
IUUC-Ola-087015	Oryzias latipes	45.35	0.00e+00	838.00
IUUC-Oga-088960	Otolemur garnettii	84.64	0.00e+00	1938.00
IUUC-Oar-089853	Ovis aries	82.01	0.00e+00	1884.00
IUUC-Ptr-091093	Pan troglodytes	97.18	0.00e+00	2258.00
IUUC-Pan-091962	Papio anubis	93.86	0.00e+00	2204.00
IUUC-Psi-093691	Pelodiscus sinensis	64.10	0.00e+00	1436.00
IUUC-Pma-094428	Petromyzon marinus	67.62	1.00e-69	256.00
IUUC-Pfo-096983	Poecilia formosa	46.52	0.00e+00	926.00
IUUC-Pab-097860	Pongo abelii	96.40	0.00e+00	2222.00
IUUC-Pca-100514	Procavia capensis	80.18	0.00e+00	662.00
IUUC-Pva-102771	Pteropus vampyrus	82.96	0.00e+00	1890.00
IUUC-Rno-105405	Rattus norvegicus	77.05	0.00e+00	1769.00
IUUC-Sha-107376	Sarcophilus harrisii	63.46	0.00e+00	1444.00
IUUC-Ssc-115819	Sus scrofa	77.97	0.00e+00	1366.00
IUUC-Tgu-117262	Taeniopygia guttata	61.74	0.00e+00	1392.00
IUUC-Tru-117601	Takifugu rubripes	47.47	0.00e+00	1006.00
IUUC-Tsy-118996	Tarsius syrichta	75.75	0.00e+00	1647.00
IUUC-Tni-120682	Tetraodon nigroviridis	41.57	0.00e+00	775.00
IUUC-Tbe-127616	Tupaia belangeri	67.52	0.00e+00	1159.00
IUUC-Ttr-129075	Tursiops truncatus	80.33	0.00e+00	1859.00
IUUC-Vpa-130108	Vicugna pacos	82.47	0.00e+00	1790.00
IUUC-Xtr-132623	Xenopus tropicalis	51.65	0.00e+00	1107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence