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Tag Content
UUCD2 ID IUUC-Mcc-054656
UUCD1 version UUC-MaM-01034
Ensembl Protein ID ENSMMUP00000044898.1
UniProt Accession H9FWM4; H9FWM4_MACMU
Genbank Protein ID AFE79033.1; AFH28894.1
Protein Name Ubiquitin-like modifier-activating enzyme 6
Genbank Nucleotide ID JSUE03033634; JU472090
Gene Name UBA6
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000003776.3 ENSMMUT00000054477.1 ENSMMUP00000044898.1
ENSMMUG00000003776.3 ENSMMUT00000005350.3 ENSMMUP00000005038.3
ENSMMUG00000003776.3 ENSMMUT00000005349.3 ENSMMUP00000005037.3
Status Unreviewed
Classification
Family E-Value Score Start End
E1 4.50e-225 748.5 443 930
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E1
   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+Gv      g+itv+D d +e+snlnrqFLfr+++++k+K+ +aa+a  +
   Q: 443  YDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVgtskekGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLK 531
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +n++++++ah +++++ +e+i+   F +k d++++aldn+earr+v+++cl++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 532  INSQIKIDAHLNKVCPATETIYndeFCTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEE 620
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl+k++s +++eg+++v  +l s++++n+++++e+a+ +f+
   Q: 621  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQV-IKLLSRRPRNWSQCVELARLKFE 708
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ di+ k++s fw+                                                         +f++
   Q: 709  KYFNHKALQLLHCFPLDIRLKDGSLFWQspkrppspikfdlneplhlsflqnaaklyatvycipfteedlsadallnilsevkiqEFKP 797
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+ +v  +s++     ++l++++l++ ++k+++++++lsfekddd+  ++d++taa+nlra++++iep +d++++k+
   Q: 798  SNKVVQTDETARKPDHVPISSEDernaiFQLEKAILSNEATKSDLQMAVLSFEKDDDHngHIDFITAASNLRAKMYSIEP-ADRFKTKR 885
           ******************999999********************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           +ag+iipaiatt+a+v+Gl+a+E+iKv+ g +fe++kn+fl++a+
   Q: 886  VAGKIIPAIATTTATVSGLVALEMIKVTGGyPFEAYKNCFLNLAI 930
           *****************************************9886 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MEGSKPVAAP QGEEASCSSW GTGSTNKNLP IMSTASVEID DALYSRQRYV LGDTAMQKMA 60
KSYVFLSGMG GLGLEIAKNL VLAGIKALTI HDTEKCQAWD LGTNFFLSED DVVNKRNRAE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-054656|E1,E1_ThiF|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCGCCGCCCG CCCCTTGACC CCCGCGGTCC CGCCTCCTTC CTACCTCCCA GTAGCCGGCG 60
GCGGTGTCTC AGGCGGCAAT GGAAGGATCC AAGCCTGTGG CCGCCCCTCA GGGGGAAGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-054656|E1,E1_ThiF|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like
Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys
PRINTS

PR01849--UBIQUITINACT
SMART

SM00985--UBA_e1_C
Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG mcc:711751
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001608 Ailuropoda melanoleuca 92.87 0.00e+00 2041.00
IUUC-Apl-004158 Anas platyrhynchos 79.92 0.00e+00 1728.00
IUUC-Aca-005349 Anolis carolinensis 80.12 0.00e+00 1756.00
IUUC-Bta-012696 Bos taurus 92.21 0.00e+00 2028.00
IUUC-Cja-019563 Callithrix jacchus 97.24 0.00e+00 2095.00
IUUC-Cfa-020951 Canis familiaris 92.59 0.00e+00 2041.00
IUUC-Cpo-022307 Cavia porcellus 88.51 0.00e+00 1929.00
IUUC-Csa-023647 Chlorocebus sabaeus 99.24 0.00e+00 2147.00
IUUC-Cho-024682 Choloepus hoffmanni 77.08 0.00e+00 939.00
IUUC-Dre-028022 Danio rerio 66.54 0.00e+00 1468.00
IUUC-Dno-029796 Dasypus novemcinctus 91.15 0.00e+00 1951.00
IUUC-Dor-030981 Dipodomys ordii 76.29 0.00e+00 1518.00
IUUC-Ete-032514 Echinops telfairi 77.73 0.00e+00 1140.00
IUUC-Eca-033697 Equus caballus 93.20 0.00e+00 2006.00
IUUC-Eeu-035323 Erinaceus europaeus 84.41 0.00e+00 1364.00
IUUC-Fca-035858 Felis catus 94.27 0.00e+00 2026.00
IUUC-Fal-036848 Ficedula albicollis 80.12 0.00e+00 1728.00
IUUC-Gmo-039326 Gadus morhua 65.66 0.00e+00 1379.00
IUUC-Gga-040747 Gallus gallus 80.02 0.00e+00 1712.00
IUUC-Gac-041406 Gasterosteus aculeatus 66.44 0.00e+00 1386.00
IUUC-Ggo-044577 Gorilla gorilla 98.58 0.00e+00 2133.00
IUUC-Hsa-046007 Homo sapiens 98.38 0.00e+00 2126.00
IUUC-Itr-048191 Ictidomys tridecemlineatus 95.88 0.00e+00 1071.00
IUUC-Lch-049992 Latimeria chalumnae 73.47 0.00e+00 1544.00
IUUC-Loc-051899 Lepisosteus oculatus 68.23 0.00e+00 1483.00
IUUC-Laf-054413 Loxodonta africana 92.31 0.00e+00 1869.00
IUUC-Meu-056463 Macropus eugenii 71.52 0.00e+00 1419.00
IUUC-Mga-059721 Meleagris gallopavo 78.24 0.00e+00 1621.00
IUUC-Mmr-060908 Microcebus murinus 91.63 0.00e+00 1999.00
IUUC-Mdo-062096 Monodelphis domestica 84.48 0.00e+00 1892.00
IUUC-Mmu-064114 Mus musculus 89.45 0.00e+00 1956.00
IUUC-Mpu-066017 Mustela putorius furo 92.49 0.00e+00 2045.00
IUUC-Mlu-068037 Myotis lucifugus 90.26 0.00e+00 1959.00
IUUC-Nle-069494 Nomascus leucogenys 98.00 0.00e+00 2122.00
IUUC-Opr-070910 Ochotona princeps 67.52 3.00e-175 609.00
IUUC-Ont-071592 Oreochromis niloticus 68.07 0.00e+00 1447.00
IUUC-Oan-073268 Ornithorhynchus anatinus 80.28 0.00e+00 1600.00
IUUC-Ocu-074296 Oryctolagus cuniculus 93.25 0.00e+00 2037.00
IUUC-Ola-086376 Oryzias latipes 67.97 0.00e+00 1397.00
IUUC-Oga-088186 Otolemur garnettii 93.92 0.00e+00 2045.00
IUUC-Oar-089307 Ovis aries 92.30 0.00e+00 2025.00
IUUC-Ptr-090609 Pan troglodytes 98.57 0.00e+00 2125.00
IUUC-Pan-092905 Papio anubis 99.80 0.00e+00 2063.00
IUUC-Psi-093489 Pelodiscus sinensis 81.10 0.00e+00 1746.00
IUUC-Pma-094203 Petromyzon marinus 64.86 3.00e-57 213.00
IUUC-Pfo-096670 Poecilia formosa 68.30 0.00e+00 1452.00
IUUC-Pab-098418 Pongo abelii 98.29 0.00e+00 2121.00
IUUC-Pca-100889 Procavia capensis 75.29 0.00e+00 1587.00
IUUC-Pva-103144 Pteropus vampyrus 82.13 0.00e+00 1762.00
IUUC-Rno-105612 Rattus norvegicus 89.73 0.00e+00 1961.00
IUUC-Sha-107388 Sarcophilus harrisii 86.32 0.00e+00 1872.00
IUUC-Sar-113128 Sorex araneus 88.70 0.00e+00 1921.00
IUUC-Ssc-116117 Sus scrofa 93.26 0.00e+00 2047.00
IUUC-Tgu-116565 Taeniopygia guttata 80.53 0.00e+00 1740.00
IUUC-Tru-118591 Takifugu rubripes 66.57 0.00e+00 1412.00
IUUC-Tsy-119436 Tarsius syrichta 82.98 0.00e+00 1771.00
IUUC-Tni-120880 Tetraodon nigroviridis 66.15 0.00e+00 1399.00
IUUC-Tbe-127714 Tupaia belangeri 80.34 0.00e+00 1415.00
IUUC-Ttr-129159 Tursiops truncatus 80.89 0.00e+00 1712.00
IUUC-Vpa-130716 Vicugna pacos 90.47 0.00e+00 1897.00
IUUC-Xtr-132947 Xenopus tropicalis 70.34 0.00e+00 1533.00
Created Date 25-Jun-2017

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