iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059326

UUCD1 version

UUC-MeG-00270

Ensembl Protein ID

ENSMGAP00000005469.1

UniProt Accession

G1N1Q4; G1N1Q4_MELGA

Protein Name

Uncharacterized protein

Gene Name

WSB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000005511.1	ENSMGAT00000006199.1	ENSMGAP00000005466.1
ENSMGAG00000005511.1	ENSMGAT00000006202.1	ENSMGAP00000005469.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	8.60e-14	50.9	349	396
E3 adaptor/Cullin RING/DCX/DWD	4.00e-33	111.8	143	177
UBD/Beta-Prp	2.00e-46	158.3	116	353

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyed 51
           ++++w++++   SL+hLCR+a r +l+++++    +LP+P++Lk++L y+d
   Q: 349  HVQFWTAPRVLSSLKHLCRKALRTFLTTYQV---LALPIPRKLKEFLTYRD 396
           689****************************...***************86 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrt 32
           gH+d v++l+f  ++  +lvs+s+D t++vWDl++
   Q: 143  GHQDVVRDLSFapNGsLILVSASRDRTLRVWDLSR 177
           8***********5446778*************976 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfspsgdkl 109
           ++latg  dg ikvw+v+tg ll sl gh++ v++++f p+g+ ilv++s+Drt++vwdls +g +v++l+gh + v+++s+sp+ + l
   Q: 116  QVLATGLNDGQIKVWEVQTGHLLFSLLGHQDVVRDLSFAPNGSlILVSASRDRTLRVWDLSrDGRQVQVLTGHVQWVYCCSISPDCSML 204
           689****************************************9****************999*********************99*** PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tgghtdsvysl 186
            s+   + + +w +++++ ++  l+gh+++v +  ++pd+ llv++s+D++v +Wd  tg+ lrtl            +  ht+s +s+
   Q: 205  CSAAGEKSALLWSMRSYTLIR-KLEGHQSSVVSCDFSPDSALLVTASYDTCVIMWDPYTGEQLRTLrhvplhsaleysSDVHTSSLRSV 292
           *********************.*******************************************************9888******** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
            f+++g +l+++++d+ +++w l+  +      +  +n ++   +p++ ++++g+ Dg +++W
   Q: 293  CFSPEGLYLATVADDRLLRIWALELRS--PVAFAPMTNGLCCMYFPHGGFIATGTRDGHVQFW 353
           ***********************9665..34556666666666667***************** PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

LTPTESSLLP GELKPGRPQQ YDWKSSCETW SVAFSSDGSW FAWSQGHCLV KLIPWPLQEA 60
EHCRASERKS HKAEAKRSRT GAKEKTLECG QIVWGLAFSA WPAAQHPDGA AGLCCQVLAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACACGGGGGG GTGAGCACCC CATGGTGTTC CCTGAGGCAA GCACCCCAAG GGCTCACCAC 60
AAGACACATG GCCAGGGGTG TGCTGAGCTG CTCAGTCTCA GCTGGATGCC CTGCTTGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002221	Ailuropoda melanoleuca	76.75	0.00e+00	628.00
IUUC-Apl-004107	Anas platyrhynchos	78.61	2.00e-143	501.00
IUUC-Aca-004354	Anolis carolinensis	74.56	4.00e-168	583.00
IUUC-Bta-012627	Bos taurus	77.69	2.00e-177	614.00
IUUC-Cja-018897	Callithrix jacchus	76.80	2.00e-175	607.00
IUUC-Cfa-020122	Canis familiaris	77.00	0.00e+00	628.00
IUUC-Cpo-022540	Cavia porcellus	78.52	0.00e+00	626.00
IUUC-Csa-023719	Chlorocebus sabaeus	77.52	1.00e-177	615.00
IUUC-Cho-024367	Choloepus hoffmanni	82.37	6.00e-144	502.00
IUUC-Dno-029021	Dasypus novemcinctus	77.86	2.00e-180	624.00
IUUC-Dor-030321	Dipodomys ordii	77.78	2.00e-178	617.00
IUUC-Ete-032955	Echinops telfairi	77.78	9.00e-178	615.00
IUUC-Eca-033485	Equus caballus	77.18	2.00e-176	611.00
IUUC-Fca-035389	Felis catus	77.32	9.00e-178	615.00
IUUC-Fal-037184	Ficedula albicollis	95.42	3.00e-159	553.00
IUUC-Gga-041014	Gallus gallus	97.06	0.00e+00	743.00
IUUC-Ggo-045585	Gorilla gorilla	77.95	5.00e-180	623.00
IUUC-Hsa-046344	Homo sapiens	77.95	3.00e-180	624.00
IUUC-Itr-049085	Ictidomys tridecemlineatus	78.09	7.00e-179	619.00
IUUC-Lch-050131	Latimeria chalumnae	66.09	1.00e-158	551.00
IUUC-Loc-052807	Lepisosteus oculatus	52.62	2.00e-117	415.00
IUUC-Laf-053528	Loxodonta africana	77.95	8.00e-177	612.00
IUUC-Mcc-055665	Macaca mulatta	77.95	3.00e-180	624.00
IUUC-Meu-056054	Macropus eugenii	76.00	1.00e-173	602.00
IUUC-Mmr-060815	Microcebus murinus	77.69	0.00e+00	627.00
IUUC-Mdo-062000	Monodelphis domestica	79.20	0.00e+00	642.00
IUUC-Mmu-063927	Mus musculus	77.84	7.00e-179	619.00
IUUC-Mpu-065726	Mustela putorius furo	77.58	1.00e-177	615.00
IUUC-Nle-069680	Nomascus leucogenys	77.69	4.00e-178	616.00
IUUC-Opr-070356	Ochotona princeps	78.03	0.00e+00	629.00
IUUC-Oan-073647	Ornithorhynchus anatinus	81.62	6.00e-133	466.00
IUUC-Ocu-073973	Oryctolagus cuniculus	78.52	0.00e+00	625.00
IUUC-Oga-088797	Otolemur garnettii	77.75	1.00e-179	622.00
IUUC-Oar-089187	Ovis aries	77.69	3.00e-177	613.00
IUUC-Ptr-091317	Pan troglodytes	77.95	5.00e-180	623.00
IUUC-Pan-092694	Papio anubis	71.13	1.00e-152	532.00
IUUC-Psi-093392	Pelodiscus sinensis	81.98	0.00e+00	648.00
IUUC-Pab-098145	Pongo abelii	77.78	6.00e-178	616.00
IUUC-Pca-100454	Procavia capensis	70.20	4.00e-157	547.00
IUUC-Pva-102986	Pteropus vampyrus	70.20	2.00e-158	551.00
IUUC-Rno-104931	Rattus norvegicus	77.12	2.00e-177	614.00
IUUC-Sha-106476	Sarcophilus harrisii	78.70	0.00e+00	637.00
IUUC-Ssc-115643	Sus scrofa	77.52	2.00e-177	614.00
IUUC-Tgu-117522	Taeniopygia guttata	67.54	3.00e-146	511.00
IUUC-Tsy-119301	Tarsius syrichta	77.53	0.00e+00	627.00
IUUC-Tni-120198	Tetraodon nigroviridis	46.72	2.00e-102	365.00
IUUC-Ttr-128683	Tursiops truncatus	77.52	1.00e-177	615.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence