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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106271
UUCD1 version UUC-SaC-00216
Ensembl Protein ID YLR129W
UniProt Accession Q12220; D6VYC4; Q05386; UTP12_YEAST
Genbank Protein ID AAB82375.1; AAB82402.1; CAA62640.1; CAA97699.1; CAA97700.1; CAA61707.1; DAA09440.1
Protein Name U3 small nucleolar RNA-associated protein 12; DOM34-interacting protein 2; U three protein 12
Genbank Nucleotide ID U53877; U53881; X91258; Z73301; Z73302; X89514; BK006945
Gene Name DIP2; UTP12; YLR129W; L3116; L9233.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YLR129W YLR129W YLR129W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFBioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-50 165.8 472 502
UBD/Beta-Prp 6.50e-86 286.6 49 254
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H + +++l++ sd ++lv+Gs D+t+k WD+
   Q: 472  HDAAIWSLDLtSDgKRLVTGSADKTVKFWDF 502
           9999*******999****************6 PP
   

   UBD/Beta-Prp
   S: 76   ikvwdlstgkcvhtlk............ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlW 164
           +++wd++tg+ v++l+            ++ ++ + l+ ++++d l++G +d +i+vwdl ++++l   ++gh+++++ ++++++g  l+sGs+D+ + +W
   Q: 49   VNIWDIKTGDLVSKLSdglppgasdargAKPAECTYLEAHKDTDLLAVGYADGVIKVWDLMSKTVLL-NFNGHKAAITLLQFDGTGTRLISGSKDSNIIVW 148
           689***********99999988888777777778889999999***********************9.9******************************** PP
   S: 165  dlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW..dlrsgdllktlqlh 263
           dl  +  l++l++ h+ds++    + +   l+s s+dg +klwdl+t +c++t ++ht   + +++   d++l++++ D +++iW  d++++++ ++l+  
   Q: 149  DLVGEVGLYKLRS-HKDSITGFWCQGE-DWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAVK--DDLLITTGTDSQVKIWklDIENDKMGGKLTEM 245
           ************9.******9999987.69*************************************..99**************9999999998888765 PP
   S: 264  n.......s 265
                   +
   Q: 246  GifekqskQ 254
           555444442 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Involved in nucleolar processing of pre-18S ribosomal RNA.
 Involved in nucleolar processing of pre-18S ribosomal RNA.
Protein Sequence
(Fasta)
MVKSYQRFEQ AAAFGVIASN ANCVWIPASS GNSNGSGPGQ LITSALEDVN IWDIKTGDLV 60
SKLSDGLPPG ASDARGAKPA ECTYLEAHKD TDLLAVGYAD GVIKVWDLMS KTVLLNFNGH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106271|E3,WD_repeat;UBD,Beta-Prp|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGTCAAAT CATACCAACG TTTTGAGCAA GCAGCTGCTT TTGGTGTAAT AGCCTCCAAT 60
GCCAATTGTG TTTGGATACC TGCGTCATCC GGAAATAGTA ATGGTAGTGG ACCAGGACAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106271|E3,WD_repeat;UBD,Beta-Prp|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04003--Utp12
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0000480--P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000447--P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472--P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0031167--P:rRNA methylation
KEGG sce:YLR129W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000784 Aegilops tauschii 33.07 4.00e-116 410.00
IUUC-Aml-001245 Ailuropoda melanoleuca 41.68 8.00e-116 409.00
IUUC-Atr-002700 Amborella trichopoda 35.43 2.00e-136 478.00
IUUC-Apl-004164 Anas platyrhynchos 33.52 3.00e-93 334.00
IUUC-Aca-004765 Anolis carolinensis 36.52 2.00e-153 534.00
IUUC-Aly-006503 Arabidopsis lyrata 35.27 8.00e-145 505.00
IUUC-Ath-006848 Arabidopsis thaliana 35.13 4.00e-146 510.00
IUUC-Ago-007909 Ashbya gossypii 68.23 0.00e+00 1308.00
IUUC-Acl-008238 Aspergillus clavatus 42.25 0.00e+00 735.00
IUUC-Afl-008544 Aspergillus flavus 40.89 0.00e+00 712.00
IUUC-Afu-008868 Aspergillus fumigatus 41.76 0.00e+00 733.00
IUUC-Ani-009367 Aspergillus nidulans 41.38 0.00e+00 709.00
IUUC-Ang-009732 Aspergillus niger 42.48 0.00e+00 762.00
IUUC-Aor-010140 Aspergillus oryzae 41.21 0.00e+00 717.00
IUUC-Ate-010572 Aspergillus terreus 41.34 0.00e+00 704.00
IUUC-Ame-010956 Astyanax mexicanus 36.66 1.00e-156 545.00
IUUC-Bgr-012296 Blumeria graminis 41.79 0.00e+00 720.00
IUUC-Bta-012716 Bos taurus 37.35 3.00e-156 543.00
IUUC-Bci-013699 Botrytis cinerea 41.12 0.00e+00 704.00
IUUC-Bdi-014525 Brachypodium distachyon 33.30 3.00e-128 450.00
IUUC-Bol-015117 Brassica oleracea 34.93 8.00e-141 492.00
IUUC-Bra-016869 Brassica rapa 35.56 1.00e-140 492.00
IUUC-Cel-018570 Caenorhabditis elegans 28.37 2.00e-87 315.00
IUUC-Cja-019425 Callithrix jacchus 37.80 9.00e-157 545.00
IUUC-Cfa-020787 Canis familiaris 37.27 3.00e-153 533.00
IUUC-Cpo-021729 Cavia porcellus 41.16 3.00e-121 427.00
IUUC-Cre-022678 Chlamydomonas reinhardtii 41.56 4.00e-92 330.00
IUUC-Csa-024098 Chlorocebus sabaeus 37.58 3.00e-158 550.00
IUUC-Cho-024495 Choloepus hoffmanni 38.59 4.00e-90 323.00
IUUC-Cin-025245 Ciona intestinalis 34.48 4.00e-86 310.00
IUUC-Cgl-026708 Colletotrichum gloeosporioides 44.89 0.00e+00 746.00
IUUC-Cne-026835 Cryptococcus neoformans 47.20 2.00e-127 447.00
IUUC-Cme-027162 Cyanidioschyzon merolae 29.56 1.00e-33 136.00
IUUC-Dre-027874 Danio rerio 37.25 3.00e-169 587.00
IUUC-Dno-028905 Dasypus novemcinctus 36.84 9.00e-154 535.00
IUUC-Dor-030383 Dipodomys ordii 36.07 6.00e-54 204.00
IUUC-Dse-031297 Dothistroma septosporum 39.26 0.00e+00 653.00
IUUC-Dme-031956 Drosophila melanogaster 31.63 2.00e-124 437.00
IUUC-Ete-032608 Echinops telfairi 35.56 8.00e-87 312.00
IUUC-Eca-034181 Equus caballus 36.63 2.00e-151 527.00
IUUC-Eeu-034495 Erinaceus europaeus 43.10 1.00e-111 395.00
IUUC-Fca-035994 Felis catus 34.11 2.00e-120 424.00
IUUC-Fal-036611 Ficedula albicollis 40.29 1.00e-116 412.00
IUUC-Fox-037807 Fusarium oxysporum 44.12 0.00e+00 753.00
IUUC-Fso-038090 Fusarium solani 44.22 0.00e+00 754.00
IUUC-Gmo-039018 Gadus morhua 34.48 4.00e-82 296.00
IUUC-Ggr-039748 Gaeumannomyces graminis 42.71 0.00e+00 756.00
IUUC-Gga-040707 Gallus gallus 40.79 1.00e-114 405.00
IUUC-Gac-042334 Gasterosteus aculeatus 43.37 7.00e-40 156.00
IUUC-Gma-043860 Glycine max 34.78 3.00e-132 464.00
IUUC-Ggo-045334 Gorilla gorilla 41.33 6.00e-118 416.00
IUUC-Hsa-046996 Homo sapiens 41.50 2.00e-117 415.00
IUUC-Hvu-047381 Hordeum vulgare 30.19 2.00e-63 234.00
IUUC-Itr-047938 Ictidomys tridecemlineatus 40.86 2.00e-114 404.00
IUUC-Kpa-049185 Komagataella pastoris 51.09 0.00e+00 934.00
IUUC-Lch-050098 Latimeria chalumnae 35.27 8.00e-139 485.00
IUUC-Lpe-050710 Leersia perrieri 33.56 3.00e-126 444.00
IUUC-Loc-052745 Lepisosteus oculatus 35.42 1.00e-149 521.00
IUUC-Lma-053104 Leptosphaeria maculans 42.73 0.00e+00 732.00
IUUC-Laf-054395 Loxodonta africana 37.78 5.00e-156 543.00
IUUC-Mcc-055077 Macaca mulatta 41.67 1.00e-118 419.00
IUUC-Meu-056418 Macropus eugenii 40.00 2.00e-86 311.00
IUUC-Mor-057031 Magnaporthe oryzae 43.67 0.00e+00 701.00
IUUC-Mpo-057420 Magnaporthe poae 42.57 0.00e+00 741.00
IUUC-Mtr-057838 Medicago truncatula 34.27 4.00e-138 483.00
IUUC-Mla-058854 Melampsora laricipopulina 36.75 1.00e-154 538.00
IUUC-Mga-060120 Meleagris gallopavo 40.79 3.00e-114 404.00
IUUC-Mvi-060407 Microbotryum violaceum 43.65 6.00e-143 499.00
IUUC-Mmr-060635 Microcebus murinus 37.23 6.00e-155 539.00
IUUC-Mdo-063023 Monodelphis domestica 41.37 4.00e-118 417.00
IUUC-Mmu-064103 Mus musculus 36.19 4.00e-157 546.00
IUUC-Mac-065569 Musa acuminata 35.42 2.00e-139 488.00
IUUC-Mpu-066462 Mustela putorius furo 37.45 6.00e-155 539.00
IUUC-Mlu-067894 Myotis lucifugus 37.32 5.00e-153 533.00
IUUC-Nfi-068321 Neosartorya fischeri 41.25 0.00e+00 715.00
IUUC-Ncr-068661 Neurospora crassa 42.97 0.00e+00 741.00
IUUC-Nle-069409 Nomascus leucogenys 37.78 2.00e-157 548.00
IUUC-Opr-070445 Ochotona princeps 41.33 1.00e-113 402.00
IUUC-Ont-072339 Oreochromis niloticus 36.11 4.00e-161 560.00
IUUC-Oan-073688 Ornithorhynchus anatinus 35.96 5.00e-147 513.00
IUUC-Ocu-074227 Oryctolagus cuniculus 37.17 5.00e-154 536.00
IUUC-Oba-075635 Oryza barthii 31.86 2.00e-120 424.00
IUUC-Obr-076897 Oryza brachyantha 33.51 1.00e-129 455.00
IUUC-Ogl-077555 Oryza glaberrima 31.86 3.00e-120 424.00
IUUC-Ogu-078724 Oryza glumaepatula 32.37 9.00e-121 426.00
IUUC-Oin-080030 Oryza indica 31.86 1.00e-118 419.00
IUUC-Olo-080687 Oryza longistaminata 30.25 3.00e-107 381.00
IUUC-Ome-081867 Oryza meridionalis 31.64 2.00e-121 428.00
IUUC-Oni-082559 Oryza nivara 31.86 2.00e-118 418.00
IUUC-Opu-083332 Oryza punctata 37.97 8.00e-117 412.00
IUUC-Oru-084455 Oryza rufipogon 31.96 2.00e-119 421.00
IUUC-Osa-085793 Oryza sativa 31.96 2.00e-119 421.00
IUUC-Ola-087395 Oryzias latipes 50.14 8.00e-101 359.00
IUUC-Olu-087768 Ostreococcus lucimarinus 38.05 1.00e-106 378.00
IUUC-Oga-088574 Otolemur garnettii 36.50 8.00e-152 528.00
IUUC-Oar-089453 Ovis aries 33.64 4.00e-126 443.00
IUUC-Ptr-090694 Pan troglodytes 41.50 5.00e-118 416.00
IUUC-Pan-092420 Papio anubis 41.17 6.00e-118 416.00
IUUC-Psi-093683 Pelodiscus sinensis 36.99 1.00e-151 528.00
IUUC-Pma-094197 Petromyzon marinus 32.91 1.00e-31 127.00
IUUC-Pno-094783 Phaeosphaeria nodorum 41.19 0.00e+00 710.00
IUUC-Ppa-095208 Physcomitrella patens 34.51 1.00e-141 495.00
IUUC-Pfo-096299 Poecilia formosa 37.06 7.00e-169 585.00
IUUC-Pab-098706 Pongo abelii 37.62 4.00e-157 546.00
IUUC-Pop-099275 Populus trichocarpa 35.03 8.00e-132 462.00
IUUC-Pca-100796 Procavia capensis 33.50 3.00e-79 288.00
IUUC-Ppe-101861 Prunus persica 35.32 3.00e-135 473.00
IUUC-Pva-103241 Pteropus vampyrus 39.20 2.00e-140 491.00
IUUC-Pgr-103432 Puccinia graminis 37.25 5.00e-155 539.00
IUUC-Ptt-103742 Puccinia triticina 38.83 4.00e-131 460.00
IUUC-Pte-104069 Pyrenophora teres 42.36 0.00e+00 686.00
IUUC-Pyt-104650 Pyrenophora triticirepentis 41.65 0.00e+00 704.00
IUUC-Rno-105219 Rattus norvegicus 35.98 5.00e-152 530.00
IUUC-Sha-107550 Sarcophilus harrisii 41.10 2.00e-116 411.00
IUUC-Sja-107664 Schizosaccharomyces japonicus 41.97 0.00e+00 679.00
IUUC-Spo-108239 Schizosaccharomyces pombe 40.67 0.00e+00 689.00
IUUC-Ssl-108626 Sclerotinia sclerotiorum 41.45 0.00e+00 731.00
IUUC-Smo-108974 Selaginella moellendorffii 34.19 3.00e-141 494.00
IUUC-Sit-110000 Setaria italica 33.87 2.00e-119 421.00
IUUC-Sly-111595 Solanum lycopersicum 34.96 5.00e-138 483.00
IUUC-Stu-112516 Solanum tuberosum 34.85 1.00e-136 479.00
IUUC-Sar-113195 Sorex araneus 41.68 1.00e-108 385.00
IUUC-Sbi-114465 Sorghum bicolor 33.09 9.00e-126 442.00
IUUC-Sre-115006 Sporisorium reilianum 32.90 5.00e-156 543.00
IUUC-Ssc-115929 Sus scrofa 42.00 2.00e-115 407.00
IUUC-Tgu-117282 Taeniopygia guttata 39.64 3.00e-113 400.00
IUUC-Tru-118406 Takifugu rubripes 42.71 4.00e-121 427.00
IUUC-Tsy-119170 Tarsius syrichta 36.65 4.00e-150 523.00
IUUC-Tni-119721 Tetraodon nigroviridis 41.32 2.00e-117 414.00
IUUC-Tca-121761 Theobroma cacao 35.68 2.00e-146 510.00
IUUC-Tre-121908 Trichoderma reesei 44.91 0.00e+00 733.00
IUUC-Tvi-122547 Trichoderma virens 44.95 0.00e+00 724.00
IUUC-Tae-125496 Triticum aestivum 33.75 9.00e-127 446.00
IUUC-Tur-126811 Triticum urartu 34.68 2.00e-126 444.00
IUUC-Tme-126987 Tuber melanosporum 44.82 0.00e+00 774.00
IUUC-Tbe-127315 Tupaia belangeri 42.05 2.00e-95 342.00
IUUC-Ttr-129165 Tursiops truncatus 40.33 1.00e-58 219.00
IUUC-Uma-129651 Ustilago maydis 33.91 2.00e-155 541.00
IUUC-Vda-129973 Verticillium dahliae 43.49 0.00e+00 729.00
IUUC-Vpa-130163 Vicugna pacos 36.44 8.00e-46 176.00
IUUC-Vvi-131402 Vitis vinifera 34.99 5.00e-134 470.00
IUUC-Xtr-132296 Xenopus tropicalis 41.29 2.00e-115 408.00
IUUC-Xma-133028 Xiphophorus maculatus 37.27 2.00e-171 594.00
IUUC-Yli-134484 Yarrowia lipolytica 45.23 0.00e+00 749.00
IUUC-Zma-135938 Zea mays 33.53 2.00e-124 437.00
Created Date 25-Jun-2017

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