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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105566
Ensembl Protein ID ENSRNOP00000064357.1
UniProt Accession M0R4R2; M0R4R2_RAT
Genbank Protein ID ENSRNOP00000064357
Protein Name Protein HIRA
Genbank Nucleotide ID AABR07034739
Gene Name Hira
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000045770.1 ENSRNOT00000075164.1 ENSRNOP00000064357.1
Annotation
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.60e-20 71.6 69 98
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H + v+c+++ ++  +l+sG+dD+ i+vW 
   Q: 69   HLACVNCVRWsNSgMYLASGGDDKLIMVWK 98
           8899******955699*************7 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
 Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Protein Sequence
(Fasta)
MKLLKPTWVN HNGKPIFSVD IHPDGTKFAT GGQGQDSGKV VIWNMSPVLQ EDDEKDENIP 60
KMLCQMDNHL ACVNCVRWSN SGMYLASGGD DKLIMVWKRA TYIGPSTVFG SSGKLANVEQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105566|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCTCTGCTC TGCCTGGCCT GTTTCTACGT CTATGCAAAC GCCCCGCTCT TCCAATAAAT 60
GCTCCAGTCT GGCCCCCTAT CCTTCTCCAT TAGGCTAGCT CCTTTATGCA TGCAATCGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105566|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat
Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated
KEGG rno:363849
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001039 Aegilops tauschii 40.28 9.00e-90 325.00
IUUC-Atr-003132 Amborella trichopoda 41.67 2.00e-88 320.00
IUUC-Aca-004733 Anolis carolinensis 80.98 0.00e+00 1567.00
IUUC-Aly-005446 Arabidopsis lyrata 36.00 6.00e-83 302.00
IUUC-Ath-007627 Arabidopsis thaliana 36.60 2.00e-85 310.00
IUUC-Ago-007766 Ashbya gossypii 31.31 3.00e-59 223.00
IUUC-Acl-008104 Aspergillus clavatus 29.14 7.00e-64 239.00
IUUC-Afl-008591 Aspergillus flavus 30.02 2.00e-64 241.00
IUUC-Afu-008781 Aspergillus fumigatus 33.33 2.00e-58 221.00
IUUC-Ang-009655 Aspergillus niger 33.42 4.00e-65 243.00
IUUC-Aor-010119 Aspergillus oryzae 30.02 6.00e-65 242.00
IUUC-Ate-010530 Aspergillus terreus 26.80 2.00e-55 211.00
IUUC-Ame-011147 Astyanax mexicanus 85.00 6.00e-53 198.00
IUUC-Bgr-012237 Blumeria graminis 33.50 1.00e-62 235.00
IUUC-Bci-013795 Botrytis cinerea 33.92 7.00e-68 252.00
IUUC-Bdi-014075 Brachypodium distachyon 42.60 5.00e-92 332.00
IUUC-Bol-016440 Brassica oleracea 35.20 4.00e-88 319.00
IUUC-Bra-016651 Brassica rapa 40.61 6.00e-87 315.00
IUUC-Cel-018692 Caenorhabditis elegans 38.10 7.00e-76 278.00
IUUC-Cja-018987 Callithrix jacchus 94.77 0.00e+00 1684.00
IUUC-Cpo-021484 Cavia porcellus 95.87 0.00e+00 1800.00
IUUC-Cre-022846 Chlamydomonas reinhardtii 36.20 7.00e-62 232.00
IUUC-Csa-023081 Chlorocebus sabaeus 95.58 0.00e+00 1789.00
IUUC-Cin-025182 Ciona intestinalis 55.24 2.00e-156 546.00
IUUC-Csv-026154 Ciona savignyi 55.85 3.00e-152 532.00
IUUC-Cgl-026655 Colletotrichum gloeosporioides 31.12 3.00e-66 247.00
IUUC-Cne-026891 Cryptococcus neoformans 41.08 6.00e-83 302.00
IUUC-Cme-027349 Cyanidioschyzon merolae 29.00 4.00e-52 200.00
IUUC-Dre-027655 Danio rerio 69.10 0.00e+00 1340.00
IUUC-Dor-030687 Dipodomys ordii 82.24 0.00e+00 743.00
IUUC-Dse-031334 Dothistroma septosporum 30.53 9.00e-63 235.00
IUUC-Dme-031746 Drosophila melanogaster 55.51 5.00e-159 555.00
IUUC-Ete-032384 Echinops telfairi 87.55 0.00e+00 1606.00
IUUC-Fca-036121 Felis catus 93.57 0.00e+00 1729.00
IUUC-Fox-037906 Fusarium oxysporum 34.86 6.00e-69 255.00
IUUC-Fso-038409 Fusarium solani 33.73 1.00e-67 251.00
IUUC-Gmo-039151 Gadus morhua 86.25 0.00e+00 702.00
IUUC-Ggr-040016 Gaeumannomyces graminis 35.04 2.00e-70 260.00
IUUC-Gga-040936 Gallus gallus 84.67 0.00e+00 1679.00
IUUC-Gac-041405 Gasterosteus aculeatus 62.67 0.00e+00 1188.00
IUUC-Gma-044252 Glycine max 29.56 4.00e-114 406.00
IUUC-Ggo-045430 Gorilla gorilla 95.09 0.00e+00 1779.00
IUUC-Hsa-046442 Homo sapiens 95.18 0.00e+00 1784.00
IUUC-Kpa-049145 Komagataella pastoris 30.88 3.00e-60 227.00
IUUC-Lch-050474 Latimeria chalumnae 75.17 0.00e+00 1411.00
IUUC-Lpe-051209 Leersia perrieri 35.03 1.00e-85 311.00
IUUC-Loc-052119 Lepisosteus oculatus 72.71 0.00e+00 1362.00
IUUC-Lma-053237 Leptosphaeria maculans 31.09 2.00e-67 250.00
IUUC-Laf-053718 Loxodonta africana 93.41 0.00e+00 1751.00
IUUC-Meu-055914 Macropus eugenii 77.05 0.00e+00 1424.00
IUUC-Mor-057090 Magnaporthe oryzae 33.97 1.00e-67 252.00
IUUC-Mpo-057364 Magnaporthe poae 32.59 1.00e-72 268.00
IUUC-Mtr-057744 Medicago truncatula 37.48 3.00e-91 330.00
IUUC-Mla-058914 Melampsora laricipopulina 41.40 2.00e-84 307.00
IUUC-Mga-060181 Meleagris gallopavo 82.56 0.00e+00 1615.00
IUUC-Mvi-060432 Microbotryum violaceum 37.78 9.00e-74 272.00
IUUC-Mmr-060871 Microcebus murinus 94.59 0.00e+00 1815.00
IUUC-Mdo-062301 Monodelphis domestica 84.34 0.00e+00 1606.00
IUUC-Mmu-063888 Mus musculus 99.01 0.00e+00 1833.00
IUUC-Mac-065137 Musa acuminata 38.84 1.00e-90 327.00
IUUC-Mlu-067542 Myotis lucifugus 92.52 0.00e+00 1698.00
IUUC-Nfi-068396 Neosartorya fischeri 33.99 2.00e-58 221.00
IUUC-Ncr-068842 Neurospora crassa 32.46 2.00e-68 254.00
IUUC-Nle-070156 Nomascus leucogenys 95.87 0.00e+00 1795.00
IUUC-Ont-072105 Oreochromis niloticus 67.92 0.00e+00 1315.00
IUUC-Ocu-074962 Oryctolagus cuniculus 95.22 0.00e+00 1771.00
IUUC-Oba-075178 Oryza barthii 35.93 2.00e-93 337.00
IUUC-Obr-076399 Oryza brachyantha 35.93 7.00e-94 338.00
IUUC-Ogu-078797 Oryza glumaepatula 35.93 2.00e-93 337.00
IUUC-Olo-081048 Oryza longistaminata 41.04 4.00e-66 247.00
IUUC-Ome-081324 Oryza meridionalis 35.75 8.00e-93 335.00
IUUC-Oni-082548 Oryza nivara 35.93 3.00e-93 337.00
IUUC-Opu-084008 Oryza punctata 42.09 5.00e-91 329.00
IUUC-Oru-084339 Oryza rufipogon 35.75 7.00e-93 335.00
IUUC-Osa-085782 Oryza sativa 35.75 7.00e-93 335.00
IUUC-Ola-087302 Oryzias latipes 72.26 0.00e+00 800.00
IUUC-Olu-087611 Ostreococcus lucimarinus 36.05 4.00e-89 322.00
IUUC-Ptr-090715 Pan troglodytes 95.28 0.00e+00 1784.00
IUUC-Psi-094053 Pelodiscus sinensis 82.65 0.00e+00 1598.00
IUUC-Pno-094985 Phaeosphaeria nodorum 32.60 6.00e-59 222.00
IUUC-Ppa-095819 Physcomitrella patens 36.09 1.00e-89 324.00
IUUC-Pfo-096857 Poecilia formosa 66.44 0.00e+00 1268.00
IUUC-Pab-098047 Pongo abelii 95.48 0.00e+00 1788.00
IUUC-Pop-099587 Populus trichocarpa 37.73 2.00e-90 327.00
IUUC-Ppe-101261 Prunus persica 38.48 4.00e-92 333.00
IUUC-Pva-102683 Pteropus vampyrus 93.61 0.00e+00 1766.00
IUUC-Pgr-103660 Puccinia graminis 40.88 1.00e-77 284.00
IUUC-Ptt-103900 Puccinia triticina 41.83 2.00e-79 290.00
IUUC-Pte-104209 Pyrenophora teres 34.27 3.00e-65 243.00
IUUC-Pyt-104802 Pyrenophora triticirepentis 34.27 7.00e-65 242.00
IUUC-Sce-106291 Saccharomyces cerevisiae 32.59 2.00e-61 230.00
IUUC-Sha-107514 Sarcophilus harrisii 79.49 0.00e+00 1467.00
IUUC-Sja-107833 Schizosaccharomyces japonicus 35.57 1.00e-81 298.00
IUUC-Spo-108162 Schizosaccharomyces pombe 36.36 1.00e-77 284.00
IUUC-Smo-109533 Selaginella moellendorffii 37.58 1.00e-91 331.00
IUUC-Sit-110730 Setaria italica 36.05 2.00e-91 330.00
IUUC-Sly-111547 Solanum lycopersicum 38.15 1.00e-93 338.00
IUUC-Stu-112705 Solanum tuberosum 38.15 8.00e-94 338.00
IUUC-Sbi-114272 Sorghum bicolor 37.88 8.00e-94 338.00
IUUC-Sre-115061 Sporisorium reilianum 34.99 2.00e-77 283.00
IUUC-Tru-117590 Takifugu rubripes 66.92 0.00e+00 1285.00
IUUC-Tni-119915 Tetraodon nigroviridis 67.00 0.00e+00 1260.00
IUUC-Tca-121765 Theobroma cacao 37.92 2.00e-91 330.00
IUUC-Tre-121887 Trichoderma reesei 30.43 2.00e-60 227.00
IUUC-Tvi-122262 Trichoderma virens 33.90 1.00e-60 228.00
IUUC-Tae-124148 Triticum aestivum 45.36 4.00e-39 156.00
IUUC-Tur-126483 Triticum urartu 43.62 9.00e-94 338.00
IUUC-Tme-127202 Tuber melanosporum 29.52 8.00e-57 215.00
IUUC-Tbe-127350 Tupaia belangeri 82.93 0.00e+00 642.00
IUUC-Ttr-129077 Tursiops truncatus 88.84 0.00e+00 1730.00
IUUC-Uma-129465 Ustilago maydis 35.40 1.00e-78 288.00
IUUC-Vda-129844 Verticillium dahliae 34.56 1.00e-66 248.00
IUUC-Vvi-131397 Vitis vinifera 37.20 1.00e-92 334.00
IUUC-Xtr-132057 Xenopus tropicalis 75.44 0.00e+00 1428.00
IUUC-Yli-134424 Yarrowia lipolytica 31.94 3.00e-66 247.00
IUUC-Zma-135839 Zea mays 37.33 7.00e-92 332.00
Created Date 25-Jun-2017

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