iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055250

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03023841

Gene Name

KLHL18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000006454.3	ENSMMUT00000009050.3	ENSMMUP00000008505.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.20e-20	73.0	38	103
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.50e-10	39.5	137	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l++g+ +f+ah+ivLaas ++F+a+f++++ e k ++++++++++p++++al++F Y g l +
   Q: 38   CDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECK-QDEIVMQGMDPSALEALINFAYNGNLAI 103
           9*************************************.************************9865 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Nclg+++fA+++ c  L+daa++fi++hF
   Q: 137  PKNCLGVRQFAETMMCAVLYDAANSFIHQHF 167
           68***************************** PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MVEDGAEELE DLVHFSVSEL PSRGYGVMEE IRRQGKLCDV TLKIGDHKFS AHRIVLAASI 60
PYFHAMFTND MMECKQDEIV MQGMDPSALE ALINFAYNGN LAIDQQNVQS LLMGASFLQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCCGAGG AGTTTCAACT ACGGCGGCCG CAGAGGCCCG TCTAATTGCT GCTCCGCGCT 60
CCGAGCCGCT GTCGGCGTGC TAGATCGCCC CGCCCTGGTT AGTGTCTAGC CGGCCGGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

mcc:711943

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001536	Ailuropoda melanoleuca	97.06	0.00e+00	1166.00
IUUC-Apl-003270	Anas platyrhynchos	88.62	0.00e+00	988.00
IUUC-Aca-005395	Anolis carolinensis	90.00	0.00e+00	1082.00
IUUC-Bta-013481	Bos taurus	97.06	0.00e+00	1176.00
IUUC-Cel-018622	Caenorhabditis elegans	44.27	1.00e-140	493.00
IUUC-Cja-019847	Callithrix jacchus	98.45	0.00e+00	1183.00
IUUC-Cfa-020341	Canis familiaris	96.37	0.00e+00	1158.00
IUUC-Cpo-021613	Cavia porcellus	95.20	0.00e+00	1069.00
IUUC-Csa-023611	Chlorocebus sabaeus	99.14	0.00e+00	1193.00
IUUC-Cho-024605	Choloepus hoffmanni	81.27	1.00e-136	480.00
IUUC-Cin-025289	Ciona intestinalis	53.93	0.00e+00	637.00
IUUC-Dre-028248	Danio rerio	82.81	0.00e+00	1009.00
IUUC-Dno-029609	Dasypus novemcinctus	95.68	0.00e+00	1156.00
IUUC-Dor-030541	Dipodomys ordii	97.66	6.00e-152	530.00
IUUC-Dme-032107	Drosophila melanogaster	54.29	0.00e+00	648.00
IUUC-Eca-033507	Equus caballus	97.02	0.00e+00	1085.00
IUUC-Eeu-034750	Erinaceus europaeus	87.69	0.00e+00	959.00
IUUC-Fca-035731	Felis catus	96.89	0.00e+00	1167.00
IUUC-Fal-036959	Ficedula albicollis	89.46	0.00e+00	1044.00
IUUC-Gga-040166	Gallus gallus	92.95	0.00e+00	1115.00
IUUC-Ggo-044853	Gorilla gorilla	98.79	0.00e+00	1187.00
IUUC-Hsa-046437	Homo sapiens	98.62	0.00e+00	1181.00
IUUC-Itr-048529	Ictidomys tridecemlineatus	97.39	0.00e+00	1075.00
IUUC-Lch-050195	Latimeria chalumnae	77.49	0.00e+00	904.00
IUUC-Loc-051787	Lepisosteus oculatus	85.64	0.00e+00	985.00
IUUC-Laf-053489	Loxodonta africana	95.85	0.00e+00	1155.00
IUUC-Meu-056871	Macropus eugenii	87.28	0.00e+00	1023.00
IUUC-Mga-059425	Meleagris gallopavo	92.95	0.00e+00	1111.00
IUUC-Mmr-061394	Microcebus murinus	98.45	0.00e+00	1191.00
IUUC-Mdo-062285	Monodelphis domestica	93.82	0.00e+00	1112.00
IUUC-Mmu-063975	Mus musculus	98.79	0.00e+00	1195.00
IUUC-Mpu-066369	Mustela putorius furo	97.41	0.00e+00	1169.00
IUUC-Mlu-067832	Myotis lucifugus	92.78	0.00e+00	1046.00
IUUC-Nle-069338	Nomascus leucogenys	91.22	0.00e+00	1066.00
IUUC-Opr-071035	Ochotona princeps	83.96	0.00e+00	914.00
IUUC-Ont-071440	Oreochromis niloticus	81.75	0.00e+00	965.00
IUUC-Ola-087275	Oryzias latipes	80.56	0.00e+00	958.00
IUUC-Oga-087921	Otolemur garnettii	97.75	0.00e+00	1175.00
IUUC-Oar-089968	Ovis aries	90.16	0.00e+00	1048.00
IUUC-Ptr-091272	Pan troglodytes	98.79	0.00e+00	1187.00
IUUC-Pan-092629	Papio anubis	98.96	0.00e+00	1189.00
IUUC-Psi-093456	Pelodiscus sinensis	92.34	0.00e+00	981.00
IUUC-Pma-094509	Petromyzon marinus	68.42	0.00e+00	786.00
IUUC-Pfo-096450	Poecilia formosa	78.60	0.00e+00	957.00
IUUC-Pab-097917	Pongo abelii	98.62	0.00e+00	1185.00
IUUC-Pca-100330	Procavia capensis	97.32	1.00e-174	606.00
IUUC-Pva-103189	Pteropus vampyrus	97.41	0.00e+00	1171.00
IUUC-Pyt-104758	Pyrenophora triticirepentis	33.75	9.00e-07	47.00
IUUC-Sha-107283	Sarcophilus harrisii	93.61	0.00e+00	1077.00
IUUC-Sar-112989	Sorex araneus	95.34	0.00e+00	1064.00
IUUC-Tgu-117146	Taeniopygia guttata	80.70	0.00e+00	907.00
IUUC-Tru-118132	Takifugu rubripes	81.29	0.00e+00	945.00
IUUC-Tsy-119058	Tarsius syrichta	81.27	6.00e-138	484.00
IUUC-Tni-120892	Tetraodon nigroviridis	78.95	0.00e+00	949.00
IUUC-Tbe-127347	Tupaia belangeri	94.82	0.00e+00	1137.00
IUUC-Ttr-128343	Tursiops truncatus	74.25	0.00e+00	773.00
IUUC-Vpa-130796	Vicugna pacos	83.94	0.00e+00	971.00
IUUC-Xtr-132077	Xenopus tropicalis	82.11	0.00e+00	942.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence