iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068224

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02002217

Gene Name

USP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001633.2	ENSMLUT00000001635.2	ENSMLUP00000021311.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-82	277.0	295	889

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl NlgNtCYmN+vLQ+L++ip+++ +ll    +  ++++ + +  +l+ s   +++ +++ k+k     ++++a++++ae+fs + q
   Q: 295  QGLPNLGNTCYMNAVLQSLFSIPPFAYDLLY---QGSPWSEIPLDALSLCLSHLLVLKDIYSVKTKERLLINIKNAISTVAEMFSDNTQ 380
           6******************************...999999887888888888888889999**************************** PP
   S: 90   qDaqEflaflldqleeelkk.eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           +Da+Efl ++ldq++ +++k ++ ++++ e+ee++s ++  a+++ +k+  ++++++F+++l ++i+c++c++v  ++e +++ls+++p
   Q: 381  NDAHEFLGHCLDQMKGNMEKlNTIWKTKIESEEENSPQQFFADNDVTKRLVCPVTTNFEVELLHSITCKACGQVVLKTEVNNYLSINLP 469
           ******************77544555555555555666666999999999*************************************** PP
   S: 178  gkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
           + ++t+++s+q+ ++ f+ +eele    y+c kc++k+ ++ ++k+++lP+vLi+hLkR+sf++  +s +k +++v + + L++s++ct
   Q: 470  QGKKTHPLSIQSTFDLFFGAEELE----YKCGKCNHKT-SVSMHKFSRLPRVLIIHLKRYSFNKF-WSLRKDDQEVIISKYLKVSSHCT 552
           ***********************9....*******999.799********************998.*********************** PP
   S: 267  s........................................................................................ 267
           +                                                                                        
   Q: 553  Estkppfplnknvhirdfhllkffhninfeilksltpstkltskskdclaphiesdkesepqkdqifglskeqkqnnlgkhsklttaes 641
           *9**********************************99999999999999999999999999999999988888888888888887777 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 642  llvnsgygtaiekellvpglmrnlentnlsvvhedegkptsgpdtsaevhlqevprnpkrkkyekssmfaavdsvtettedfsedeknk 730
           77777777777777777777777777777777777777777777777777777777766666666666666666666666666655555 PP
   S: 268  .............peekqke..................................................................... 274
                        +                                                                           
   Q: 731  iseefsnvpgqtpQ-----Ceklkiyeealwqallqslpktdaqchtdnltrptelslqeanenshgasssnknlghkdflakkmteak 814
           55555555555550.....0555555555555555555555555555555556666666666666666666667777777777777777 PP
   S: 275  ..........kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
                     ++ Y+Li+v++H G +l+sGHY++++++ ++k W++++D +V++++e+ ++e + +t+Y++fY++
   Q: 815  akkpnpkirdHYAYRLIGVISHLGnTLHSGHYISDAYDFERKvWFNYNDMQVSSIQEDLMQEARLRTGYIFFYMH 889
           7777888888****************************99999*******************999********98 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAAIIAHGFV QIWNMDTGMS KLKEAFIETV ERKKKARLVI RFSTGEYTTF QLGNNIKNIV 60
FRSYGENQNY LHLTFQNTSF LFIRKLSSRD AKNLTMFLDR VHQNNLQSPF RTDMGGSVFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCTA TAATAGCACA TGGTTTTGTT CAAATATGGA ACATGGATAC TGGGATGTCT 60
AAATTGAAAG AAGCATTTAT TGAAACAGTG GAAAGAAAGA AGAAAGCTAG ATTGGTGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002281	Ailuropoda melanoleuca	61.89	0.00e+00	1048.00
IUUC-Apl-004033	Anas platyrhynchos	37.80	3.00e-147	516.00
IUUC-Aca-005370	Anolis carolinensis	36.85	2.00e-143	503.00
IUUC-Ame-011884	Astyanax mexicanus	35.34	4.00e-114	405.00
IUUC-Bta-012832	Bos taurus	52.44	0.00e+00	845.00
IUUC-Cja-019801	Callithrix jacchus	52.30	0.00e+00	855.00
IUUC-Cfa-020088	Canis familiaris	61.56	0.00e+00	1075.00
IUUC-Cpo-022049	Cavia porcellus	41.78	3.00e-172	598.00
IUUC-Cre-022867	Chlamydomonas reinhardtii	27.64	3.00e-17	84.00
IUUC-Csa-023990	Chlorocebus sabaeus	57.16	0.00e+00	939.00
IUUC-Cho-024390	Choloepus hoffmanni	39.71	4.00e-29	123.00
IUUC-Cin-025496	Ciona intestinalis	38.03	6.00e-35	142.00
IUUC-Csv-025812	Ciona savignyi	32.34	2.00e-26	114.00
IUUC-Dre-028255	Danio rerio	37.17	4.00e-92	333.00
IUUC-Dno-028968	Dasypus novemcinctus	48.53	0.00e+00	751.00
IUUC-Dor-030370	Dipodomys ordii	43.60	0.00e+00	655.00
IUUC-Ete-033046	Echinops telfairi	46.05	6.00e-90	325.00
IUUC-Eca-034060	Equus caballus	63.30	0.00e+00	1057.00
IUUC-Eeu-034492	Erinaceus europaeus	41.92	3.00e-80	293.00
IUUC-Fca-035628	Felis catus	60.74	0.00e+00	1040.00
IUUC-Fal-037640	Ficedula albicollis	38.32	2.00e-148	520.00
IUUC-Gmo-039600	Gadus morhua	31.71	3.00e-107	383.00
IUUC-Gga-040126	Gallus gallus	42.75	1.00e-121	430.00
IUUC-Gac-041557	Gasterosteus aculeatus	35.73	8.00e-88	318.00
IUUC-Ggo-045311	Gorilla gorilla	57.92	0.00e+00	953.00
IUUC-Hsa-046292	Homo sapiens	57.48	0.00e+00	942.00
IUUC-Itr-047983	Ictidomys tridecemlineatus	53.23	0.00e+00	880.00
IUUC-Lch-050357	Latimeria chalumnae	34.53	8.00e-106	378.00
IUUC-Loc-052849	Lepisosteus oculatus	34.84	6.00e-105	375.00
IUUC-Laf-054311	Loxodonta africana	49.41	0.00e+00	773.00
IUUC-Mcc-055452	Macaca mulatta	47.22	0.00e+00	736.00
IUUC-Meu-056273	Macropus eugenii	54.13	3.00e-27	117.00
IUUC-Mga-059814	Meleagris gallopavo	41.87	3.00e-124	439.00
IUUC-Mmr-061542	Microcebus murinus	59.42	0.00e+00	1000.00
IUUC-Mdo-062974	Monodelphis domestica	39.57	2.00e-156	546.00
IUUC-Mmu-064069	Mus musculus	38.24	7.00e-142	498.00
IUUC-Mpu-066846	Mustela putorius furo	59.75	0.00e+00	1044.00
IUUC-Nle-069425	Nomascus leucogenys	47.10	0.00e+00	733.00
IUUC-Opr-070989	Ochotona princeps	33.80	2.00e-87	316.00
IUUC-Ont-072441	Oreochromis niloticus	32.93	3.00e-91	330.00
IUUC-Oan-073151	Ornithorhynchus anatinus	50.69	5.00e-56	211.00
IUUC-Ocu-073860	Oryctolagus cuniculus	51.57	0.00e+00	813.00
IUUC-Ola-087007	Oryzias latipes	35.97	5.00e-83	302.00
IUUC-Oga-088020	Otolemur garnettii	47.71	0.00e+00	727.00
IUUC-Oar-089263	Ovis aries	52.44	0.00e+00	863.00
IUUC-Ptr-091299	Pan troglodytes	40.77	6.00e-161	561.00
IUUC-Pan-092928	Papio anubis	56.89	0.00e+00	915.00
IUUC-Psi-093176	Pelodiscus sinensis	39.15	1.00e-148	520.00
IUUC-Pma-094331	Petromyzon marinus	42.60	3.00e-71	263.00
IUUC-Ppa-095732	Physcomitrella patens	27.72	2.00e-24	107.00
IUUC-Pfo-096503	Poecilia formosa	35.35	3.00e-87	316.00
IUUC-Pab-098555	Pongo abelii	57.47	0.00e+00	973.00
IUUC-Pca-100925	Procavia capensis	45.09	0.00e+00	647.00
IUUC-Pva-103163	Pteropus vampyrus	39.62	4.00e-110	392.00
IUUC-Rno-105766	Rattus norvegicus	39.37	2.00e-145	509.00
IUUC-Sha-106610	Sarcophilus harrisii	38.05	8.00e-136	478.00
IUUC-Sar-113624	Sorex araneus	45.94	0.00e+00	632.00
IUUC-Ssc-116225	Sus scrofa	62.31	0.00e+00	1079.00
IUUC-Tgu-116971	Taeniopygia guttata	43.50	2.00e-121	430.00
IUUC-Tru-117932	Takifugu rubripes	48.96	6.00e-72	265.00
IUUC-Tsy-119113	Tarsius syrichta	45.25	0.00e+00	678.00
IUUC-Tni-119842	Tetraodon nigroviridis	45.06	3.00e-70	259.00
IUUC-Tbe-127615	Tupaia belangeri	57.56	5.00e-130	458.00
IUUC-Ttr-129071	Tursiops truncatus	53.64	0.00e+00	919.00
IUUC-Vpa-130653	Vicugna pacos	60.97	0.00e+00	1041.00
IUUC-Xtr-132949	Xenopus tropicalis	35.37	4.00e-129	455.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence