iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010970

Ensembl Protein ID

ENSAMXP00000013535.1

UniProt Accession

W5L123; W5L123_ASTMX

Genbank Protein ID

ENSAMXP00000013535

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01088666

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000013109.1	ENSAMXT00000013517.1	ENSAMXP00000013517.1
ENSAMXG00000013109.1	ENSAMXT00000013535.1	ENSAMXP00000013535.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-108	361.9	652	1382

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++++  ++ ++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 652  TGLVNLGNTCFMNSVIQSLSNTRELRDYFHDrAFETEINCSNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 738
           7******************************8999**************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++de     a++++k++n+s+i+dlFqgq+ks+++       s +++p
   Q: 739  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSD--GRQDEvvaeeAWQRHKMRNDSFIVDLFQGQYKSKLV-------SITFDP 816
           ********************************9998..5555556777**********************9885.......79**** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           fl+l++p+p+k++                                                                          
   Q: 817  FLYLPVPLPQKQKVLSVfyfakephkkpikflvsvskensstaevlesisrsvrvkpenlrltevvksrfsriflpshsldrvsssd 903
           ************76444********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 904  mlfcfevlskeltkekvvllrvhqrlqvpsipipkcaacqkppladdeklkrctrcyrvgycnqacqrnhwpnhkalcrpnsenvgl 990
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 991  pflisvpesrlsyarlnqllegysrysvnvfrppfqsgrtspdsslsrgdqpslsgtvpeglepeeeapsaggeagdsqeqstcgsg 1077
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1078 vsgpetesgqatahsggdldklstrttdsgfseqalssqdpfreketscektvkpeaavpgyqqssecsngstsqfyislldssnss 1164
           *************************************************************************************** PP
   S: 186  ............................................................slqdcLesftkeeelegenkyycekck 212
                                                                       +l++cL+ ftk+e l  e+++yc+kc+
   Q: 1165 keekledkddavlevpddctlelvwknnerlkeyvlvrskelefdedpgsasetaraghfTLEQCLNLFTKPEVLAPEEAWYCPKCQ 1251
           *************************************************************************************** PP
   S: 213  kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvay 298
           +++ea+k+l l++lP+vLi++LkRfsf++  +++ kin+ v+fp + Ldls+fc+ ++e+++++ +Y+L+av++H+G++ +GHY+ay
   Q: 1252 QHREASKQLLLWRLPNVLIIQLKRFSFRSFIWRD-KINDMVDFPVRnLDLSKFCIGQKEDVQQPPIYDLYAVINHYGGMIGGHYTAY 1337
           ******************************8886.**********9***************************************** PP
   S: 299  vknekgk........WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           ++  ++k        W lfdDs+Vt+v+e++v++   + aYvlfY+rr
   Q: 1338 ARLPNDKnsqrsdvgWRLFDDSTVTTVEESQVVT---RYAYVLFYRRR 1382
           **9554455677888*******************...********996 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MASSSTASSE TSRRRTQRGP DDSSSTSKKK QKDRANQESR EAKRAATGAN TEAKKDVFLD 60
WKQNANEVIV RLRCGEGTLR LENVATAFSD TACQVRLPNG REWGCHLHAE IEGSCSKVQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACGCGGTTA CAGTACACAG ATTACTGACC CCTGCTGGTT CTAAATTAAC TAAGAGATAC 60
TGTCCGGAAG TCTGAACGCA CTGAGGCAGA TTACGGGTGT GATCTGAGCT CCTCTCCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND

PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2

Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0046872--F:metal ion binding
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001999	Ailuropoda melanoleuca	70.61	0.00e+00	1376.00
IUUC-Apl-003368	Anas platyrhynchos	71.47	0.00e+00	1399.00
IUUC-Aca-004267	Anolis carolinensis	72.78	0.00e+00	1419.00
IUUC-Bta-012905	Bos taurus	69.74	0.00e+00	1352.00
IUUC-Cel-018257	Caenorhabditis elegans	43.45	9.00e-91	328.00
IUUC-Cja-018789	Callithrix jacchus	71.25	0.00e+00	1385.00
IUUC-Cfa-021004	Canis familiaris	71.03	0.00e+00	1357.00
IUUC-Cpo-021529	Cavia porcellus	70.20	0.00e+00	1328.00
IUUC-Csa-024035	Chlorocebus sabaeus	71.50	0.00e+00	1395.00
IUUC-Cho-025036	Choloepus hoffmanni	71.06	0.00e+00	638.00
IUUC-Cin-025451	Ciona intestinalis	41.60	1.00e-81	298.00
IUUC-Dre-028556	Danio rerio	72.67	0.00e+00	1947.00
IUUC-Dno-029240	Dasypus novemcinctus	69.04	0.00e+00	1288.00
IUUC-Dor-030495	Dipodomys ordii	68.21	0.00e+00	849.00
IUUC-Ete-032741	Echinops telfairi	70.62	0.00e+00	1353.00
IUUC-Eca-033661	Equus caballus	70.42	0.00e+00	1377.00
IUUC-Eeu-034648	Erinaceus europaeus	75.43	5.00e-170	592.00
IUUC-Fca-035646	Felis catus	70.93	0.00e+00	1365.00
IUUC-Fal-037094	Ficedula albicollis	68.52	0.00e+00	1440.00
IUUC-Gmo-038869	Gadus morhua	73.55	0.00e+00	1417.00
IUUC-Gga-041170	Gallus gallus	58.34	0.00e+00	1495.00
IUUC-Gac-041901	Gasterosteus aculeatus	75.11	0.00e+00	1512.00
IUUC-Ggo-044708	Gorilla gorilla	71.09	0.00e+00	1379.00
IUUC-Hsa-046791	Homo sapiens	71.20	0.00e+00	1380.00
IUUC-Itr-048892	Ictidomys tridecemlineatus	71.69	0.00e+00	1314.00
IUUC-Lch-050456	Latimeria chalumnae	62.66	0.00e+00	1124.00
IUUC-Loc-052861	Lepisosteus oculatus	59.20	0.00e+00	1461.00
IUUC-Laf-053788	Loxodonta africana	70.95	0.00e+00	1348.00
IUUC-Mcc-055693	Macaca mulatta	71.30	0.00e+00	1388.00
IUUC-Meu-055921	Macropus eugenii	71.48	0.00e+00	1188.00
IUUC-Mga-059879	Meleagris gallopavo	67.50	0.00e+00	1394.00
IUUC-Mmr-060802	Microcebus murinus	71.02	0.00e+00	1383.00
IUUC-Mdo-061856	Monodelphis domestica	72.56	0.00e+00	1352.00
IUUC-Mmu-063874	Mus musculus	71.52	0.00e+00	1375.00
IUUC-Mpu-066166	Mustela putorius furo	70.53	0.00e+00	1354.00
IUUC-Nle-070161	Nomascus leucogenys	71.20	0.00e+00	1382.00
IUUC-Opr-071015	Ochotona princeps	69.60	0.00e+00	1336.00
IUUC-Ont-072308	Oreochromis niloticus	66.41	0.00e+00	1768.00
IUUC-Oan-072723	Ornithorhynchus anatinus	71.17	0.00e+00	1350.00
IUUC-Ocu-073938	Oryctolagus cuniculus	71.28	0.00e+00	1351.00
IUUC-Ola-086375	Oryzias latipes	79.47	0.00e+00	1544.00
IUUC-Oga-088297	Otolemur garnettii	70.22	0.00e+00	1358.00
IUUC-Oar-089675	Ovis aries	69.53	0.00e+00	1198.00
IUUC-Ptr-091621	Pan troglodytes	71.09	0.00e+00	1378.00
IUUC-Pan-092118	Papio anubis	71.50	0.00e+00	1395.00
IUUC-Pma-094154	Petromyzon marinus	50.24	2.00e-108	386.00
IUUC-Pfo-097246	Poecilia formosa	77.77	0.00e+00	1552.00
IUUC-Pab-098551	Pongo abelii	70.38	0.00e+00	1362.00
IUUC-Pca-100158	Procavia capensis	68.23	0.00e+00	1297.00
IUUC-Pva-103160	Pteropus vampyrus	70.86	0.00e+00	1337.00
IUUC-Rno-105355	Rattus norvegicus	70.31	0.00e+00	1348.00
IUUC-Sha-107057	Sarcophilus harrisii	73.39	0.00e+00	1376.00
IUUC-Sar-113011	Sorex araneus	64.54	0.00e+00	981.00
IUUC-Ssc-115761	Sus scrofa	71.00	0.00e+00	1357.00
IUUC-Tgu-116956	Taeniopygia guttata	59.21	0.00e+00	749.00
IUUC-Tru-118739	Takifugu rubripes	76.29	0.00e+00	1530.00
IUUC-Tsy-118827	Tarsius syrichta	77.49	0.00e+00	680.00
IUUC-Tni-119921	Tetraodon nigroviridis	73.58	0.00e+00	1506.00
IUUC-Tbe-128017	Tupaia belangeri	68.46	0.00e+00	1312.00
IUUC-Ttr-128869	Tursiops truncatus	70.41	0.00e+00	1334.00
IUUC-Vpa-130427	Vicugna pacos	63.93	1.00e-177	617.00
IUUC-Xtr-132734	Xenopus tropicalis	72.67	0.00e+00	1398.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence