iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066002

Ensembl Protein ID

ENSMPUP00000009598.1

UniProt Accession

M3YE41; M3YE41_MUSPF

Genbank Protein ID

ENSMPUP00000009598

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AEYP01045951

Gene Name

WHSC1L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000009674.1	ENSMPUT00000009754.1	ENSMPUP00000009598.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.10e-10	40.6	702	746

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCr 52
           +vC +C+++g+   sl+ Ce  C++ fH +Cl+l+   +lp+ + +iC +C+
   Q: 702  TVCQICENSGD---SLIPCEGeCCKHFHLECLGLA---SLPDGK-FICVECK 746
           79*********...5********************...*****7.******7 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MDFSFSFMQG IMGNTIQQPP QLIDSANIRQ EDAFDNNSDI VEDGGQTPYE ATLQQGFQYP 60
PTTEDLPPLT NGYPPSISMY ETQTKYQSYN QYPNGSANGF GAVRNFSPTD YYHSEIPNTR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGATGAG AGAAAGGGAA AGTTAAGGAT GCTGGAGCAG AACAATGGAT TTCTCTTTCT 60
CTTTCATGCA AGGGATCATG GGAAACACAA TTCAGCAACC ACCTCAACTC ATTGACTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000310	Aegilops tauschii	29.41	8.00e-13	68.90
IUUC-Aml-001809	Ailuropoda melanoleuca	97.82	0.00e+00	1800.00
IUUC-Apl-004027	Anas platyrhynchos	77.77	0.00e+00	2061.00
IUUC-Aca-005380	Anolis carolinensis	82.81	0.00e+00	2231.00
IUUC-Ame-011234	Astyanax mexicanus	60.49	0.00e+00	1455.00
IUUC-Bta-013575	Bos taurus	92.92	0.00e+00	2638.00
IUUC-Bra-017733	Brassica rapa	32.00	4.00e-13	70.50
IUUC-Cja-020013	Callithrix jacchus	95.90	0.00e+00	2776.00
IUUC-Cfa-021060	Canis familiaris	97.98	0.00e+00	2726.00
IUUC-Cpo-021834	Cavia porcellus	93.67	0.00e+00	2575.00
IUUC-Csa-023370	Chlorocebus sabaeus	95.97	0.00e+00	2775.00
IUUC-Cho-025058	Choloepus hoffmanni	87.82	0.00e+00	1128.00
IUUC-Dre-027664	Danio rerio	59.89	0.00e+00	1485.00
IUUC-Dno-029302	Dasypus novemcinctus	93.68	0.00e+00	2621.00
IUUC-Eca-033626	Equus caballus	93.34	0.00e+00	2644.00
IUUC-Fca-035556	Felis catus	97.50	0.00e+00	2759.00
IUUC-Fal-037101	Ficedula albicollis	82.66	0.00e+00	2209.00
IUUC-Gmo-038901	Gadus morhua	57.27	0.00e+00	1553.00
IUUC-Gga-040366	Gallus gallus	83.03	0.00e+00	2181.00
IUUC-Gac-042047	Gasterosteus aculeatus	62.28	0.00e+00	1362.00
IUUC-Ggo-044695	Gorilla gorilla	92.86	0.00e+00	2646.00
IUUC-Hsa-046080	Homo sapiens	96.24	0.00e+00	2773.00
IUUC-Itr-048622	Ictidomys tridecemlineatus	95.20	0.00e+00	2704.00
IUUC-Lch-050544	Latimeria chalumnae	70.27	0.00e+00	1647.00
IUUC-Loc-052656	Lepisosteus oculatus	65.80	0.00e+00	1615.00
IUUC-Laf-054112	Loxodonta africana	94.73	0.00e+00	2680.00
IUUC-Mcc-054956	Macaca mulatta	95.97	0.00e+00	2770.00
IUUC-Meu-056051	Macropus eugenii	86.58	0.00e+00	1232.00
IUUC-Mga-060139	Meleagris gallopavo	85.31	0.00e+00	2260.00
IUUC-Mmr-060789	Microcebus murinus	94.78	0.00e+00	2737.00
IUUC-Mdo-062908	Monodelphis domestica	89.94	0.00e+00	2510.00
IUUC-Mmu-063165	Mus musculus	86.05	0.00e+00	2388.00
IUUC-Nle-069417	Nomascus leucogenys	95.51	0.00e+00	2597.00
IUUC-Ont-071900	Oreochromis niloticus	59.39	0.00e+00	1638.00
IUUC-Oan-072857	Ornithorhynchus anatinus	89.51	0.00e+00	2518.00
IUUC-Ocu-073809	Oryctolagus cuniculus	94.80	0.00e+00	2667.00
IUUC-Obr-076122	Oryza brachyantha	30.95	4.00e-09	55.10
IUUC-Ogu-078030	Oryza glumaepatula	30.30	4.00e-13	68.90
IUUC-Ola-087085	Oryzias latipes	59.35	0.00e+00	1609.00
IUUC-Oga-088289	Otolemur garnettii	93.95	0.00e+00	2632.00
IUUC-Oar-089398	Ovis aries	93.26	0.00e+00	2631.00
IUUC-Ptr-090510	Pan troglodytes	96.04	0.00e+00	2768.00
IUUC-Pan-092291	Papio anubis	95.90	0.00e+00	2776.00
IUUC-Psi-093547	Pelodiscus sinensis	86.49	0.00e+00	2336.00
IUUC-Pma-094747	Petromyzon marinus	48.99	0.00e+00	1080.00
IUUC-Pfo-096669	Poecilia formosa	59.53	0.00e+00	1606.00
IUUC-Pab-097727	Pongo abelii	96.11	0.00e+00	2760.00
IUUC-Pca-100474	Procavia capensis	86.89	0.00e+00	2327.00
IUUC-Pva-102539	Pteropus vampyrus	93.29	0.00e+00	2391.00
IUUC-Rno-105685	Rattus norvegicus	89.48	0.00e+00	2441.00
IUUC-Sha-107287	Sarcophilus harrisii	90.49	0.00e+00	2505.00
IUUC-Sar-113547	Sorex araneus	88.83	0.00e+00	2541.00
IUUC-Ssc-116208	Sus scrofa	96.31	0.00e+00	2794.00
IUUC-Tgu-117006	Taeniopygia guttata	85.10	0.00e+00	2303.00
IUUC-Tru-118375	Takifugu rubripes	59.35	0.00e+00	1645.00
IUUC-Tsy-119323	Tarsius syrichta	95.41	0.00e+00	2694.00
IUUC-Tni-120509	Tetraodon nigroviridis	59.79	0.00e+00	1648.00
IUUC-Tca-121456	Theobroma cacao	32.84	3.00e-20	93.60
IUUC-Tae-124687	Triticum aestivum	29.41	8.00e-13	68.90
IUUC-Ttr-128240	Tursiops truncatus	93.25	0.00e+00	2596.00
IUUC-Vpa-130666	Vicugna pacos	94.51	0.00e+00	2648.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence