iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000022546.3	ENSXETT00000048809.3	ENSXETP00000048809.3
ENSXETG00000022546.3	ENSXETT00000064203.1	ENSXETP00000059783.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-27	95.0	561	598
UBD/Beta-Prp	1.10e-43	149.7	415	633

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H d vt+la  ++  +l sGs+D++i++W+l + ++++
   Q: 561  HLDAVTSLAVdPNgLYLMSGSHDCSIRLWNLESKTCIQ 598
           99*********77799***************9999987 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsvls.....lsfspsgdklvsGshdrtirvwdletgqc 128
             ++gh++ ++ + +s   + l+++s D+ti++w+    ++ ++t++ +++ + +     + ++p g + ++  h    +v +++t + 
   Q: 415  GAYEGHSDSIWGLVYSAVHQRLLSASADGTIRIWNAAeVSPALSTFN-ENQGLSTmqsifVLSNPVGMYHAASKHNFKQNVINMQTLKA 502
           44567777777777777777777777777777775441333444444.44444441111111223344444444444444444444444 PP
   S: 129  lee.........tlsghdgvvncvvvhpdgnllvsGslDrtvrl.Wdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklw 207
           +            +++++  +n  ++h+ +++ vs ++ +   + ++   gkl++ +   h d+v+sl++d+ng +l+sgs+d +++lw
   Q: 503  VALrivcclfymRQTQTKCNINFYTFHSRTRIAVSHHNTKEPSVaFC-VIGKLIHSMVA-HLDAVTSLAVDPNGLYLMSGSHDCSIRLW 589
           44477777777666666666777777777777777666555444144.59*******98.***************************** PP
   S: 208  dlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           +l++++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 590  NLESKTCIQEFTAHRkksdESIHDVAFHPSKCYIASAGADALAK 633
           ***************999999*****************997655 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

IWKQSRQLLR QYLQEVGYTD TILDVKSKRV RSLLGLSADS SDRLTDTNQD SMVNGTETEL 60
PNPLVLGKPD MTDSASVLET FKFLENAAAE FSDEEDEEEN ESRDKTIIDS ATIVRRRIIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAGC AGGCGGGGCC CGGCGTATTT TTCAATAACA ATAACAATTC GCTGCTGTCC 60
GCTGGTGCTG GCCCAGGTGG TGCCGGGAAA GGGTTCGAGG CTGGTGCAGC AGATGCGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dre-028560	Danio rerio	55.00	1.00e-175	609.00
IUUC-Fal-037353	Ficedula albicollis	64.18	0.00e+00	671.00
IUUC-Meu-055946	Macropus eugenii	56.39	1.00e-139	489.00
IUUC-Oan-072950	Ornithorhynchus anatinus	69.69	0.00e+00	789.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence