iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020730

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03008785

Gene Name

KLHL38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000001012.3	ENSCAFT00000001555.3	ENSCAFP00000001430.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.60e-19	69.2	46	111
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.40e-08	31.5	145	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv ++ g +e+++h++vLa+sS++F+a+f ++++e++ + +v++k+++++ ++++++++Ytg++++
   Q: 46   TDVSICTGTQEVPCHRSVLASSSPYFRAMFCSNFRERR-EAKVQLKGIEAGTLEQIVSYVYTGQVRI 111
           7************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaald 25
           ++Nclg++r++++++c+ Lk++a++
   Q: 145  PSNCLGMIRLSEILSCETLKKKARE 169
           89*********************98 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MLPLGTSAPP GRMDEELPDG LLFKDHDFSS ELLRQLNGFR QNRMLTDVSI CTGTQEVPCH 60
RSVLASSSPY FRAMFCSNFR ERREAKVQLK GIEAGTLEQI VSYVYTGQVR ITADNVLPLM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGACAGTC ACATGTCATC ACAGTGGAAA GTACATATGC AACTATTCTT AGCTCTGGAA 60
TGTATACACT GTCTCCCTGC CCAGTGCTTC TTTCCCGAAG TTCTAGAAAA CTGCGAAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030596--KLHL24
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:2000312--P:regulation of kainate selective glutamate receptor activity

KEGG

cfa:609348

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001590	Ailuropoda melanoleuca	91.75	0.00e+00	1131.00
IUUC-Apl-003717	Anas platyrhynchos	70.83	0.00e+00	850.00
IUUC-Aca-005179	Anolis carolinensis	67.94	0.00e+00	870.00
IUUC-Ame-010815	Astyanax mexicanus	54.70	0.00e+00	664.00
IUUC-Bta-013356	Bos taurus	85.91	0.00e+00	1034.00
IUUC-Cja-019411	Callithrix jacchus	86.77	0.00e+00	1069.00
IUUC-Cpo-022406	Cavia porcellus	80.52	0.00e+00	971.00
IUUC-Csa-023904	Chlorocebus sabaeus	85.64	0.00e+00	1052.00
IUUC-Dre-028345	Danio rerio	55.57	0.00e+00	677.00
IUUC-Dno-029809	Dasypus novemcinctus	83.85	0.00e+00	1030.00
IUUC-Dor-030675	Dipodomys ordii	78.11	1.00e-135	476.00
IUUC-Ete-032256	Echinops telfairi	80.49	0.00e+00	761.00
IUUC-Eeu-034796	Erinaceus europaeus	84.20	0.00e+00	1016.00
IUUC-Fca-036124	Felis catus	92.24	0.00e+00	1102.00
IUUC-Fal-036887	Ficedula albicollis	68.75	0.00e+00	844.00
IUUC-Gmo-039299	Gadus morhua	54.45	0.00e+00	646.00
IUUC-Gga-040534	Gallus gallus	70.49	0.00e+00	827.00
IUUC-Gac-041280	Gasterosteus aculeatus	54.18	0.00e+00	675.00
IUUC-Ggo-045490	Gorilla gorilla	87.29	0.00e+00	1048.00
IUUC-Hsa-045672	Homo sapiens	86.60	0.00e+00	1041.00
IUUC-Itr-048640	Ictidomys tridecemlineatus	84.66	0.00e+00	1020.00
IUUC-Lch-050292	Latimeria chalumnae	63.41	0.00e+00	798.00
IUUC-Loc-051771	Lepisosteus oculatus	56.01	0.00e+00	703.00
IUUC-Laf-053679	Loxodonta africana	84.54	0.00e+00	1010.00
IUUC-Mcc-055329	Macaca mulatta	85.31	0.00e+00	1047.00
IUUC-Meu-056835	Macropus eugenii	69.70	2.00e-124	439.00
IUUC-Mga-059373	Meleagris gallopavo	71.45	0.00e+00	804.00
IUUC-Mmr-061575	Microcebus murinus	88.21	0.00e+00	1077.00
IUUC-Mdo-062142	Monodelphis domestica	75.95	0.00e+00	914.00
IUUC-Mmu-063499	Mus musculus	82.01	0.00e+00	1023.00
IUUC-Mpu-066730	Mustela putorius furo	93.81	0.00e+00	1123.00
IUUC-Mlu-067782	Myotis lucifugus	87.07	0.00e+00	1067.00
IUUC-Nle-069814	Nomascus leucogenys	86.25	0.00e+00	1031.00
IUUC-Opr-070240	Ochotona princeps	80.49	0.00e+00	736.00
IUUC-Ont-071799	Oreochromis niloticus	54.67	0.00e+00	675.00
IUUC-Oan-072938	Ornithorhynchus anatinus	68.98	0.00e+00	824.00
IUUC-Ocu-074650	Oryctolagus cuniculus	85.44	0.00e+00	1041.00
IUUC-Ola-086611	Oryzias latipes	56.81	0.00e+00	663.00
IUUC-Oga-088645	Otolemur garnettii	85.40	0.00e+00	1059.00
IUUC-Oar-090062	Ovis aries	85.67	0.00e+00	1041.00
IUUC-Ptr-091181	Pan troglodytes	80.41	0.00e+00	968.00
IUUC-Pan-092350	Papio anubis	85.31	0.00e+00	1046.00
IUUC-Psi-093340	Pelodiscus sinensis	71.70	0.00e+00	874.00
IUUC-Pma-094164	Petromyzon marinus	40.78	3.00e-112	399.00
IUUC-Pfo-096935	Poecilia formosa	51.90	0.00e+00	650.00
IUUC-Pab-098553	Pongo abelii	86.43	0.00e+00	1072.00
IUUC-Pca-100886	Procavia capensis	84.88	0.00e+00	1018.00
IUUC-Pva-102455	Pteropus vampyrus	85.91	0.00e+00	1035.00
IUUC-Pte-104106	Pyrenophora teres	25.00	8.00e-10	57.40
IUUC-Pyt-104515	Pyrenophora triticirepentis	25.19	1.00e-08	53.50
IUUC-Rno-105744	Rattus norvegicus	81.66	0.00e+00	1017.00
IUUC-Sha-106885	Sarcophilus harrisii	75.30	0.00e+00	931.00
IUUC-Tgu-116582	Taeniopygia guttata	69.27	0.00e+00	852.00
IUUC-Tru-117998	Takifugu rubripes	54.43	0.00e+00	678.00
IUUC-Tni-120407	Tetraodon nigroviridis	55.51	0.00e+00	646.00
IUUC-Tvi-122551	Trichoderma virens	24.54	1.00e-06	45.80
IUUC-Tbe-127407	Tupaia belangeri	77.50	0.00e+00	820.00
IUUC-Xtr-132841	Xenopus tropicalis	68.10	0.00e+00	833.00
IUUC-Xma-134084	Xiphophorus maculatus	57.14	0.00e+00	675.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence