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Tag Content
UUCD2 ID IUUC-Mcc-055542
UUCD1 version UUC-MaM-01093
Ensembl Protein ID ENSMMUP00000047546.1
UniProt Accession A0A1D5QHM4; A0A1D5QHM4_MACMU
Genbank Protein ID ENSMMUP00000047546
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID JSUE03001724
Gene Name USP33
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000018326.3 ENSMMUT00000058076.1 ENSMMUP00000047546.1
ENSMMUG00000018326.3 ENSMMUT00000071747.1 ENSMMUP00000057500.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 6.60e-115 385.0 190 719
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tGlkN+gNtCYmN++LQ+Lsn+p+l++++l+     +   +++++k +++ks+ kl++elw ks+ ++v p++l++ +k++++ f+gy+
   Q: 190  TGLKNIGNTCYMNAALQALSNCPPLTQFFLD-----CGGLARTDKKPAICKSYLKLMTELWhKSRPGSVVPTNLFQGIKTVNPTFRGYS 273
           7******************************.....999999*******************99************************** PP
   S: 89   qqDaqEflaflldqleeelkk........eknkpkeeeeeedkselsde........................................ 129
           qqDaqEfl++l+d l+eelk+         ++ ++ee++eedks+++ +                                        
   Q: 274  QQDAQEFLRCLMDLLHEELKEqvmeveedPQTITTEETMEEDKSQSDVDfqscescsnsdkaenengsrgfsednnettmliqddenns 362
           *******************8899998887777777777788877777779*************************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 363  emskdwqkekicnkinkvnsegeldkdrdsisetvdlnnqetvkvqihsraseyitdvhsndlstpqilpsnegvnprlsasppksgnl 451
           ***************************************************************************************** PP
   S: 130  ................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke................. 185
                           +++k++kk++s+isd+F+g++ s+++cl+cd+vs++ e+f+dlslp+pgke+ +k+                 
   Q: 452  wpglapphkkaqsaspKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLhssshptsivkagscge 540
           ****************9**************************************************99888***************** PP
   S: 186  ................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfsee 242
                                           +lqdcL++f++++el+g+n+y+cekckk+++ +k +k++k+Pe+L++hLkRf  ++e
   Q: 541  ayapqgwiaffmeyvkrfvvscvpswfwgpvvTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEILCIHLKRF--RHE 627
           ************************************************************************************..999 PP
   S: 243  qksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgst 329
            ++++ki+++v+fple Ldl+pf+++++ +q   ++Y+L++v++H+G++ssGHY+ay++n+ ++ W++fdD++Vtev+e++v++   ++
   Q: 628  LMFSTKISTHVSFPLEgLDLQPFLAKDSPAQ--IVTYDLLSVICHHGTASSGHYIAYCRNNLNNlWYEFDDQSVTEVSESTVQN---AE 711
           9*************************88777..9**************************88889*******************...** PP
   S: 330  aYvlfYkr 337
           aYvlfY++
   Q: 712  AYVLFYRK 719
           ******98 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MTGSDSHIII LTLSINGLNV LPHFESLGKQ EKIPNKMSAF RNHCPHLDSV GEITKEDLIQ 60
KSHGTCQDCK VRGPNLWACL ENRCSYVGCG ESQVDHSTIH SQETKHYLTV NLTTLRVWCY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055542|DUB,USP|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTCGAGGCT CCGCCCCCAC CTCCCCTGAC GCCCGAGACG CCTGCGGCGA CCCCGGAGAC 60
ACCGGAAGGA GCCGTGGCTG CTGCGGGAAG TCGCCGGTTC GGGAGGCGGA CACCCCGAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055542|DUB,USP|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001742 Ailuropoda melanoleuca 96.78 0.00e+00 1805.00
IUUC-Apl-003987 Anas platyrhynchos 82.81 0.00e+00 1493.00
IUUC-Aca-004713 Anolis carolinensis 77.98 0.00e+00 1427.00
IUUC-Bta-013132 Bos taurus 97.26 0.00e+00 1780.00
IUUC-Cja-018811 Callithrix jacchus 98.17 0.00e+00 1840.00
IUUC-Cfa-021158 Canis familiaris 95.17 0.00e+00 1798.00
IUUC-Cpo-021910 Cavia porcellus 89.92 0.00e+00 1594.00
IUUC-Csa-023130 Chlorocebus sabaeus 99.78 0.00e+00 1821.00
IUUC-Cho-024383 Choloepus hoffmanni 79.42 0.00e+00 687.00
IUUC-Csv-025889 Ciona savignyi 43.87 1.00e-35 142.00
IUUC-Dre-028639 Danio rerio 70.41 0.00e+00 1246.00
IUUC-Dno-029416 Dasypus novemcinctus 94.96 0.00e+00 1724.00
IUUC-Ete-032994 Echinops telfairi 79.35 0.00e+00 868.00
IUUC-Eca-034248 Equus caballus 96.66 0.00e+00 1805.00
IUUC-Eeu-035357 Erinaceus europaeus 77.80 0.00e+00 1324.00
IUUC-Fca-036013 Felis catus 94.47 0.00e+00 1731.00
IUUC-Fal-037509 Ficedula albicollis 82.46 0.00e+00 1490.00
IUUC-Gmo-038944 Gadus morhua 65.95 0.00e+00 1187.00
IUUC-Gga-040647 Gallus gallus 81.82 0.00e+00 1466.00
IUUC-Gac-041752 Gasterosteus aculeatus 70.17 0.00e+00 1254.00
IUUC-Hsa-045694 Homo sapiens 97.99 0.00e+00 1849.00
IUUC-Itr-049041 Ictidomys tridecemlineatus 97.04 0.00e+00 1769.00
IUUC-Lch-050400 Latimeria chalumnae 70.73 0.00e+00 1268.00
IUUC-Loc-052616 Lepisosteus oculatus 72.64 0.00e+00 1326.00
IUUC-Laf-053493 Loxodonta africana 95.84 0.00e+00 1761.00
IUUC-Meu-056645 Macropus eugenii 74.07 0.00e+00 1304.00
IUUC-Mga-060019 Meleagris gallopavo 82.85 0.00e+00 1260.00
IUUC-Mmr-061241 Microcebus murinus 94.08 0.00e+00 1767.00
IUUC-Mmu-063786 Mus musculus 93.08 0.00e+00 1696.00
IUUC-Mpu-065772 Mustela putorius furo 97.19 0.00e+00 1475.00
IUUC-Mlu-067732 Myotis lucifugus 94.87 0.00e+00 1774.00
IUUC-Nle-069528 Nomascus leucogenys 97.59 0.00e+00 1811.00
IUUC-Opr-070606 Ochotona princeps 90.73 0.00e+00 1608.00
IUUC-Ont-071495 Oreochromis niloticus 71.41 0.00e+00 1266.00
IUUC-Oan-073695 Ornithorhynchus anatinus 86.27 0.00e+00 1051.00
IUUC-Ocu-074457 Oryctolagus cuniculus 93.47 0.00e+00 1724.00
IUUC-Ola-086739 Oryzias latipes 69.88 0.00e+00 1293.00
IUUC-Oga-088720 Otolemur garnettii 95.82 0.00e+00 1796.00
IUUC-Oar-089921 Ovis aries 96.16 0.00e+00 1807.00
IUUC-Ptr-090526 Pan troglodytes 98.92 0.00e+00 1838.00
IUUC-Pan-092396 Papio anubis 98.94 0.00e+00 1852.00
IUUC-Psi-092971 Pelodiscus sinensis 83.83 0.00e+00 1560.00
IUUC-Pfo-097415 Poecilia formosa 70.30 0.00e+00 1270.00
IUUC-Pab-098740 Pongo abelii 99.12 0.00e+00 1834.00
IUUC-Pca-100598 Procavia capensis 83.83 0.00e+00 904.00
IUUC-Pva-102820 Pteropus vampyrus 93.17 0.00e+00 1521.00
IUUC-Rno-104894 Rattus norvegicus 92.87 0.00e+00 1708.00
IUUC-Sha-107244 Sarcophilus harrisii 78.67 0.00e+00 1411.00
IUUC-Sar-113665 Sorex araneus 93.54 0.00e+00 1771.00
IUUC-Ssc-115793 Sus scrofa 94.30 0.00e+00 1697.00
IUUC-Tgu-117487 Taeniopygia guttata 83.71 0.00e+00 1464.00
IUUC-Tru-117694 Takifugu rubripes 68.68 0.00e+00 1277.00
IUUC-Tsy-119598 Tarsius syrichta 84.79 0.00e+00 1507.00
IUUC-Tni-120189 Tetraodon nigroviridis 67.35 0.00e+00 1202.00
IUUC-Tbe-128125 Tupaia belangeri 85.16 3.00e-120 426.00
IUUC-Ttr-128269 Tursiops truncatus 93.00 0.00e+00 1664.00
IUUC-Vpa-130598 Vicugna pacos 94.52 0.00e+00 1752.00
IUUC-Xtr-132044 Xenopus tropicalis 75.05 0.00e+00 1323.00
Created Date 25-Jun-2017

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