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Tag Content
iUUCD ID IUUC-Ocu-074361
Ensembl Protein ID ENSOCUP00000021041.1
UniProt Accession G1TVF7; G1TVF7_RABIT
Protein Name Phosphoinositide phospholipase C
Gene Name PLCG1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000008231.3 ENSOCUT00000023432.1 ENSOCUP00000021041.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 4.70e-12 45.7 795 852
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekl 62
           +k  v++l+dy+aq +deLt++k  +++ +  e+q++gW++g  +  gk+ l fP+n+ve++
   Q: 795  FKCAVKALFDYKAQREDELTFTKSAIIQNV--EKQEGGWWRG--DYGGKKQLwFPSNYVEEM 852
           56789************************9..9*********..676666655******985 PP
   
Organism Oryctolagus cuniculus
Protein Sequence
(Fasta)
ERGVPSPCAN SCCSSTPTEA ELHLCRSLEV GTVMTLFYSK KSQRPERKTF QVKLETRQIT 60
WSRGADKIEG AIDIREIKEI RPGKTSRDFD RYQEDPAFRP DQSHCFVILY GMEFRLKTLS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ocu-074361|UBD,SH3|Oryctolagus cuniculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGCGGGGCG TACCATGGCG CCCCGCGCCC CCGCTTGCGG CCTGGCCGGG GGTCGCGGGG 60
CGCAGGCGCG GTGGGCCGGG GGCGGGGGTC CTCCCCACGG GCGCGCGGGC GCCTTTGTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ocu-074361|UBD,SH3|Oryctolagus cuniculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer
Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3
Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005911--C:cell-cell junction
GO:0008180--C:COP9 signalosome
GO:0005829--C:cytosol
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0005509--F:calcium ion binding
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0019722--P:calcium-mediated signaling
GO:0016477--P:cell migration
GO:0071364--P:cellular response to epidermal growth factor stimulus
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0001701--P:in utero embryonic development
GO:0009395--P:phospholipid catabolic process
GO:0045766--P:positive regulation of angiogenesis
GO:0043536--P:positive regulation of blood vessel endothelial cell migration
GO:0051281--P:positive regulation of release of sequestered calcium ion into cytosol
GO:0050852--P:T cell receptor signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001452 Ailuropoda melanoleuca 94.92 0.00e+00 2498.00
IUUC-Apl-003541 Anas platyrhynchos 69.26 0.00e+00 1722.00
IUUC-Aca-005291 Anolis carolinensis 84.54 0.00e+00 2195.00
IUUC-Ame-011004 Astyanax mexicanus 68.53 0.00e+00 1755.00
IUUC-Bta-012660 Bos taurus 95.75 0.00e+00 2394.00
IUUC-Cja-019206 Callithrix jacchus 94.81 0.00e+00 2486.00
IUUC-Cfa-020257 Canis familiaris 96.08 0.00e+00 2393.00
IUUC-Cpo-022391 Cavia porcellus 89.65 0.00e+00 2334.00
IUUC-Csa-024170 Chlorocebus sabaeus 94.14 0.00e+00 1808.00
IUUC-Cin-025520 Ciona intestinalis 47.79 0.00e+00 1076.00
IUUC-Dre-027944 Danio rerio 71.98 0.00e+00 1840.00
IUUC-Dno-029440 Dasypus novemcinctus 95.02 0.00e+00 2289.00
IUUC-Dor-031001 Dipodomys ordii 94.67 0.00e+00 2490.00
IUUC-Eca-033809 Equus caballus 96.32 0.00e+00 2405.00
IUUC-Fca-036510 Felis catus 95.58 0.00e+00 2384.00
IUUC-Fal-037541 Ficedula albicollis 86.00 0.00e+00 2048.00
IUUC-Gmo-038630 Gadus morhua 65.39 0.00e+00 1417.00
IUUC-Gga-040142 Gallus gallus 87.19 0.00e+00 2253.00
IUUC-Ggo-045063 Gorilla gorilla 95.13 0.00e+00 2509.00
IUUC-Hsa-046428 Homo sapiens 95.05 0.00e+00 2506.00
IUUC-Itr-048245 Ictidomys tridecemlineatus 95.56 0.00e+00 2454.00
IUUC-Lch-049766 Latimeria chalumnae 79.23 0.00e+00 1934.00
IUUC-Loc-052285 Lepisosteus oculatus 76.85 0.00e+00 1992.00
IUUC-Laf-053365 Loxodonta africana 94.69 0.00e+00 2362.00
IUUC-Mcc-054871 Macaca mulatta 94.57 0.00e+00 2476.00
IUUC-Meu-056724 Macropus eugenii 87.58 0.00e+00 2134.00
IUUC-Mga-059329 Meleagris gallopavo 85.84 0.00e+00 2123.00
IUUC-Mmr-061110 Microcebus murinus 94.82 0.00e+00 2495.00
IUUC-Mdo-062448 Monodelphis domestica 92.03 0.00e+00 2434.00
IUUC-Mmu-063565 Mus musculus 94.75 0.00e+00 2485.00
IUUC-Mpu-066683 Mustela putorius furo 95.20 0.00e+00 2506.00
IUUC-Mlu-067779 Myotis lucifugus 94.77 0.00e+00 2361.00
IUUC-Nle-069219 Nomascus leucogenys 94.53 0.00e+00 2053.00
IUUC-Opr-070766 Ochotona princeps 92.31 0.00e+00 1424.00
IUUC-Ont-072524 Oreochromis niloticus 73.76 0.00e+00 1913.00
IUUC-Oan-073214 Ornithorhynchus anatinus 89.80 9.00e-48 182.00
IUUC-Ola-086820 Oryzias latipes 72.95 0.00e+00 1925.00
IUUC-Oga-088172 Otolemur garnettii 95.75 0.00e+00 2515.00
IUUC-Oar-090306 Ovis aries 92.48 0.00e+00 2304.00
IUUC-Ptr-090682 Pan troglodytes 95.05 0.00e+00 2508.00
IUUC-Pan-092835 Papio anubis 95.75 0.00e+00 1790.00
IUUC-Psi-093344 Pelodiscus sinensis 85.00 0.00e+00 2223.00
IUUC-Pfo-096984 Poecilia formosa 72.06 0.00e+00 1871.00
IUUC-Pab-097871 Pongo abelii 95.48 0.00e+00 2459.00
IUUC-Pca-100772 Procavia capensis 88.24 0.00e+00 2287.00
IUUC-Pva-102790 Pteropus vampyrus 95.86 0.00e+00 2467.00
IUUC-Rno-105974 Rattus norvegicus 94.97 0.00e+00 2499.00
IUUC-Sar-112995 Sorex araneus 93.30 0.00e+00 2396.00
IUUC-Ssc-115360 Sus scrofa 95.04 0.00e+00 2491.00
IUUC-Tgu-116585 Taeniopygia guttata 84.14 0.00e+00 2154.00
IUUC-Tru-117742 Takifugu rubripes 73.36 0.00e+00 1931.00
IUUC-Tsy-119259 Tarsius syrichta 94.29 0.00e+00 825.00
IUUC-Tni-120833 Tetraodon nigroviridis 66.91 0.00e+00 1670.00
IUUC-Tbe-127504 Tupaia belangeri 86.84 0.00e+00 1226.00
IUUC-Ttr-128650 Tursiops truncatus 95.06 0.00e+00 1284.00
IUUC-Xtr-132862 Xenopus tropicalis 76.83 0.00e+00 1960.00
Created Date 25-Jun-2017

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