iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-070001

Ensembl Protein ID

ENSNLEP00000008279.1

UniProt Accession

G1R507; G1R507_NOMLE

Genbank Protein ID

ENSNLEP00000008279

Protein Name

Coronin

Genbank Nucleotide ID

ADFV01052942

Gene Name

CORO1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000006804.2	ENSNLET00000008670.1	ENSNLEP00000008279.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-16	58.7	131	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 131  GHTGPVLDIDWcphNDQVIASGSEDCTVMVWQI 163
           8***********977799*************86 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MYGPGSQLGK SGNNSWAKKR GCSIACQGSL TSAQLHAPSI GERPLSHMPW KDTMRRVVRQ 60
SKFRHVFGQA VKNDQCYDDI RVSRVTWDSS FCAVNPRFVA IIIEASGGGA FLVLPLHKTG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTATGGGC CTGGTAGTCA GCTGGGAAAG TCTGGCAATA ACAGCTGGGC TAAGAAACGT 60
GGATGCTCAA TTGCCTGCCA AGGGTCTCTT ACTTCAGCCC AGCTACATGC CCCCAGCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027333--CORO1C
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0030036--P:actin cytoskeleton organization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:2000394--P:positive regulation of lamellipodium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-019948	Callithrix jacchus	97.30	0.00e+00	829.00
IUUC-Cfa-020591	Canis familiaris	95.57	0.00e+00	808.00
IUUC-Ggo-044477	Gorilla gorilla	99.26	0.00e+00	847.00
IUUC-Hsa-046610	Homo sapiens	99.01	0.00e+00	843.00
IUUC-Itr-048583	Ictidomys tridecemlineatus	92.36	0.00e+00	784.00
IUUC-Meu-056732	Macropus eugenii	90.39	3.00e-180	624.00
IUUC-Mmr-061130	Microcebus murinus	93.60	0.00e+00	783.00
IUUC-Mdo-062851	Monodelphis domestica	87.89	0.00e+00	639.00
IUUC-Ocu-074569	Oryctolagus cuniculus	93.60	0.00e+00	793.00
IUUC-Ssc-115348	Sus scrofa	92.38	0.00e+00	771.00
IUUC-Tbe-127679	Tupaia belangeri	87.82	0.00e+00	630.00
IUUC-Vpa-130339	Vicugna pacos	99.40	0.00e+00	697.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence