iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RAID2
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.20e-07	31.5	63	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC ++f   ++ p+ l+CgHvf+++Cl ++ +       +  CP Cr
   Q: 63   CLICVSPFdgiFKLPKRLDCGHVFCLECLARLSLATAGGGDAVACPMCR 111
           ******9944422255566**********999777777888889****8 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MPCPRLPWLR RHRTSQGSGP SSPSTVSAPN SPSRGEDEDA EEEEGDGTPG SGPILPPTSP 60
MECLICVSPF DGIFKLPKRL DCGHVFCLEC LARLSLATAG GGDAVACPMC RAPTRLAPRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCAGAACG GAAGAGACGC TGCAATCCCG CACAAGGAAA GGTGTCTACA GGTGGGTGTC 60
TTGCAAAGTG ACCAGAGTCA GTTGTTTCTG TTTGAGGAGT TAGCTCTCAT AACCTGAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding

KEGG

mmu:381845

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-019712	Callithrix jacchus	82.26	2.00e-52	199.00
IUUC-Cfa-020515	Canis familiaris	76.63	5.00e-68	251.00
IUUC-Csa-023296	Chlorocebus sabaeus	71.64	2.00e-58	219.00
IUUC-Dre-028812	Danio rerio	41.24	6.00e-17	81.60
IUUC-Dor-031130	Dipodomys ordii	59.46	2.00e-08	52.00
IUUC-Gmo-038633	Gadus morhua	41.84	4.00e-17	79.30
IUUC-Gac-042137	Gasterosteus aculeatus	46.00	4.00e-17	81.60
IUUC-Ggo-044823	Gorilla gorilla	90.74	2.00e-24	105.00
IUUC-Hsa-046242	Homo sapiens	78.28	1.00e-49	190.00
IUUC-Lch-050304	Latimeria chalumnae	44.00	8.00e-20	90.10
IUUC-Loc-052136	Lepisosteus oculatus	49.40	4.00e-14	70.90
IUUC-Meu-056717	Macropus eugenii	43.66	5.00e-10	57.40
IUUC-Mmr-061708	Microcebus murinus	69.00	8.00e-61	227.00
IUUC-Mdo-062101	Monodelphis domestica	42.25	8.00e-10	56.60
IUUC-Nle-069438	Nomascus leucogenys	72.43	9.00e-59	220.00
IUUC-Ocu-074595	Oryctolagus cuniculus	59.46	3.00e-08	51.60
IUUC-Oga-088916	Otolemur garnettii	64.37	2.00e-65	242.00
IUUC-Pab-098138	Pongo abelii	77.69	3.00e-48	185.00
IUUC-Rno-105774	Rattus norvegicus	86.79	9.00e-96	343.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence