iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-041051

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-like modifier-activating enzyme 5; UFM1-activating enzyme; Ubiquitin activating enzyme-like protein; Ubiquitin-activating enzyme E1 domain-containing protein 1

Genbank Nucleotide ID

AY620963

Gene Name

UBA5; UBAL; UBE1DC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000032382.1	ENSGALT00000066702.1	ENSGALP00000057947.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E1	87.95	1.00e-167	587.00	IUUC-Hsa-046777

Active Site

Position(s)	Description	Evidence
243	Glycyl thioester intermediate	{ECO:0000250}

Organism

Gallus gallus

Functional Description
(View)

E1-like enzyme which activates UFM1 and SUMO2.

Protein Sequence
(Fasta)

MGTLAEAAGA ADGSVAFPEA AAESRRVAAM AEGGRVELLE RRVRELEREL ELARGGRASA 60
RARIETMSPE VTDSNPYSRL MALKRMGIVK DYEKIRTFTV AIVGVGGVGS VTAEMLTRCG 120

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Nucleotide Sequence
(Fasta)

ATGGGAACGC TCGCTGAGGC GGCGGGAGCG GCGGACGGTT CCGTGGCGTT CCCGGAAGCC 60
GCGGCCGAGA GCAGACGTGT CGCTGCCATG GCGGAGGGAG GGCGGGTGGA GCTGCTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc

Interpro

IPR029752--D-isomer_DH_CS1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0071566--F:UFM1 activating enzyme activity
GO:1990592--P:protein K69-linked ufmylation
GO:0071569--P:protein ufmylation

KEGG

gga:414879

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001324	Ailuropoda melanoleuca	87.40	2.00e-175	607.00
IUUC-Atr-002660	Amborella trichopoda	57.87	1.00e-113	402.00
IUUC-Apl-003722	Anas platyrhynchos	95.73	3.00e-178	617.00
IUUC-Aca-004584	Anolis carolinensis	88.39	1.00e-173	602.00
IUUC-Aly-005881	Arabidopsis lyrata	56.35	7.00e-113	400.00
IUUC-Ath-007286	Arabidopsis thaliana	59.12	1.00e-116	412.00
IUUC-Ame-011679	Astyanax mexicanus	82.35	1.00e-147	514.00
IUUC-Bta-012517	Bos taurus	86.85	4.00e-176	610.00
IUUC-Bdi-014894	Brachypodium distachyon	59.94	3.00e-110	391.00
IUUC-Bol-016054	Brassica oleracea	62.21	9.00e-117	413.00
IUUC-Bra-016708	Brassica rapa	60.61	1.00e-118	419.00
IUUC-Cel-018424	Caenorhabditis elegans	63.44	1.00e-123	436.00
IUUC-Cja-019825	Callithrix jacchus	92.95	3.00e-128	450.00
IUUC-Cfa-021160	Canis familiaris	87.67	1.00e-174	605.00
IUUC-Cpo-022255	Cavia porcellus	83.70	1.00e-171	595.00
IUUC-Csa-023827	Chlorocebus sabaeus	87.40	8.00e-180	622.00
IUUC-Cho-025078	Choloepus hoffmanni	82.34	3.00e-169	587.00
IUUC-Cin-025217	Ciona intestinalis	72.65	6.00e-150	523.00
IUUC-Dre-027578	Danio rerio	85.96	2.00e-171	595.00
IUUC-Dno-029330	Dasypus novemcinctus	84.53	2.00e-171	594.00
IUUC-Dor-030425	Dipodomys ordii	70.23	2.00e-100	358.00
IUUC-Dme-031645	Drosophila melanogaster	64.16	3.00e-129	454.00
IUUC-Ete-032912	Echinops telfairi	72.93	1.00e-45	177.00
IUUC-Eca-033247	Equus caballus	87.12	3.00e-177	613.00
IUUC-Eeu-034472	Erinaceus europaeus	86.57	2.00e-167	581.00
IUUC-Fca-035684	Felis catus	87.23	5.00e-177	613.00
IUUC-Fal-037654	Ficedula albicollis	92.12	0.00e+00	638.00
IUUC-Gmo-039449	Gadus morhua	66.13	2.00e-127	448.00
IUUC-Gac-042325	Gasterosteus aculeatus	83.15	8.00e-177	612.00
IUUC-Gma-043136	Glycine max	63.17	2.00e-121	428.00
IUUC-Ggo-044414	Gorilla gorilla	86.36	2.00e-174	604.00
IUUC-Hsa-046777	Homo sapiens	86.63	8.00e-177	612.00
IUUC-Hvu-047549	Hordeum vulgare	58.19	9.00e-96	343.00
IUUC-Itr-048175	Ictidomys tridecemlineatus	85.83	4.00e-176	610.00
IUUC-Lch-050142	Latimeria chalumnae	85.05	4.00e-178	617.00
IUUC-Lpe-050769	Leersia perrieri	65.72	9.00e-101	359.00
IUUC-Loc-052405	Lepisosteus oculatus	85.10	7.00e-170	589.00
IUUC-Laf-054152	Loxodonta africana	86.58	5.00e-175	606.00
IUUC-Mcc-055618	Macaca mulatta	87.93	1.00e-166	578.00
IUUC-Meu-056486	Macropus eugenii	88.50	3.00e-166	577.00
IUUC-Mtr-057871	Medicago truncatula	60.00	2.00e-120	425.00
IUUC-Mga-059284	Meleagris gallopavo	98.12	0.00e+00	678.00
IUUC-Mmr-061242	Microcebus murinus	88.47	2.00e-173	601.00
IUUC-Mdo-063034	Monodelphis domestica	86.68	4.00e-175	607.00
IUUC-Mmu-064322	Mus musculus	81.33	5.00e-170	590.00
IUUC-Mac-065128	Musa acuminata	66.01	9.00e-68	254.00
IUUC-Mpu-066438	Mustela putorius furo	86.85	2.00e-174	604.00
IUUC-Mlu-067578	Myotis lucifugus	86.85	7.00e-175	606.00
IUUC-Nle-069542	Nomascus leucogenys	86.36	6.00e-177	613.00
IUUC-Opr-070710	Ochotona princeps	83.24	3.00e-171	594.00
IUUC-Ont-072067	Oreochromis niloticus	86.46	3.00e-173	600.00
IUUC-Oan-073593	Ornithorhynchus anatinus	87.50	2.00e-172	598.00
IUUC-Ocu-073964	Oryctolagus cuniculus	85.60	8.00e-168	582.00
IUUC-Oba-075476	Oryza barthii	64.22	8.00e-115	406.00
IUUC-Obr-076517	Oryza brachyantha	61.63	9.00e-113	399.00
IUUC-Ogu-078664	Oryza glumaepatula	64.53	4.00e-115	407.00
IUUC-Olo-081012	Oryza longistaminata	64.22	1.00e-114	406.00
IUUC-Ome-081129	Oryza meridionalis	64.22	8.00e-115	406.00
IUUC-Oni-082265	Oryza nivara	64.91	2.00e-114	405.00
IUUC-Opu-084121	Oryza punctata	61.81	2.00e-113	402.00
IUUC-Oru-084451	Oryza rufipogon	63.24	8.00e-99	353.00
IUUC-Osa-086132	Oryza sativa	64.22	8.00e-115	406.00
IUUC-Ola-086842	Oryzias latipes	81.77	4.00e-166	577.00
IUUC-Oga-088160	Otolemur garnettii	87.70	1.00e-176	612.00
IUUC-Oar-089362	Ovis aries	87.12	4.00e-178	616.00
IUUC-Ptr-091256	Pan troglodytes	86.63	3.00e-177	613.00
IUUC-Pan-092913	Papio anubis	88.00	2.00e-168	585.00
IUUC-Psi-093740	Pelodiscus sinensis	91.45	2.00e-167	580.00
IUUC-Pma-094485	Petromyzon marinus	84.30	3.00e-109	387.00
IUUC-Ppa-095673	Physcomitrella patens	64.13	5.00e-112	397.00
IUUC-Pfo-096196	Poecilia formosa	83.60	1.00e-172	598.00
IUUC-Pab-098449	Pongo abelii	86.10	3.00e-178	617.00
IUUC-Pop-099049	Populus trichocarpa	58.20	4.00e-113	400.00
IUUC-Pca-100917	Procavia capensis	83.26	4.00e-111	394.00
IUUC-Ppe-101797	Prunus persica	59.21	3.00e-120	424.00
IUUC-Pva-102852	Pteropus vampyrus	86.96	2.00e-178	617.00
IUUC-Rno-105213	Rattus norvegicus	80.53	1.00e-169	588.00
IUUC-Sha-107569	Sarcophilus harrisii	85.83	1.00e-174	605.00
IUUC-Smo-109146	Selaginella moellendorffii	65.22	6.00e-113	400.00
IUUC-Sit-109794	Setaria italica	61.22	3.00e-114	405.00
IUUC-Sly-111622	Solanum lycopersicum	57.94	9.00e-115	406.00
IUUC-Stu-112522	Solanum tuberosum	64.67	1.00e-114	406.00
IUUC-Sar-113045	Sorex araneus	75.89	1.00e-148	519.00
IUUC-Sbi-113861	Sorghum bicolor	62.54	1.00e-111	395.00
IUUC-Ssc-115290	Sus scrofa	86.23	2.00e-147	514.00
IUUC-Tgu-117125	Taeniopygia guttata	92.35	0.00e+00	645.00
IUUC-Tru-118041	Takifugu rubripes	82.61	3.00e-175	607.00
IUUC-Tsy-119300	Tarsius syrichta	78.00	1.00e-140	492.00
IUUC-Tni-120310	Tetraodon nigroviridis	82.34	4.00e-165	573.00
IUUC-Tca-121405	Theobroma cacao	57.66	4.00e-116	411.00
IUUC-Tae-123656	Triticum aestivum	61.38	4.00e-113	401.00
IUUC-Tur-125985	Triticum urartu	61.10	4.00e-113	400.00
IUUC-Tbe-127478	Tupaia belangeri	70.68	3.00e-140	491.00
IUUC-Ttr-128169	Tursiops truncatus	68.49	3.00e-128	451.00
IUUC-Vpa-130508	Vicugna pacos	81.14	5.00e-147	513.00
IUUC-Vvi-131252	Vitis vinifera	61.30	5.00e-116	410.00
IUUC-Xtr-132776	Xenopus tropicalis	85.64	3.00e-173	600.00
IUUC-Xma-133110	Xiphophorus maculatus	84.68	1.00e-176	612.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence