iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071660

Ensembl Protein ID

ENSONIP00000012385.1

UniProt Accession

I3JU40; I3JU40_ORENI

Genbank Protein ID

ENSONIP00000012385

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01001094

Gene Name

cdc20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000009858.1	ENSONIT00000012394.1	ENSONIP00000012385.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-28	97.2	350	378
E3 adaptor/Cullin RING/APC_C/CDC20	8.60e-135	449.3	214	524

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvW 28
           Ht +v++l++ +d ++l+sG++D+ + +W
   Q: 350  HTQEVCGLKWsPDgRYLASGGNDNLVCIW 378
           9**********999*************** PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldap+lr+dfylnLldWss+n lavaL++svylw+a++gd++ l+++ +e+d+++s++w++eg++lavGt++ +v+++Dve++k+
   Q: 214  PDRILDAPDLRNDFYLNLLDWSSRNFLAVALHNSVYLWDATQGDIILLMKMeREEDYICSLAWTKEGSYLAVGTSDCKVQLWDVENQKR 302
           689************************************************8899********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....... 170
           +r++++h+arvg+LsWn+++lssGsr+g+i+h+dvrv+++++stl++h+qevCGlkw+ d+++LasGGnDn v +w  +++        
   Q: 303  LRSMASHTARVGSLSWNDHILSSGSRSGHIHHHDVRVADHHISTLTSHTQEVCGLKWSPDGRYLASGGNDNLVCIWPRAQEGsagndsq 391
           ****************************************************************************9987766677665 PP
   S: 171  PlkkfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslsk 259
            ++ ++eh++avka+aw+Pwq+++LasGGGt+Dr+i++wn+++g++++++dt+sq++sl++++++kelvs+hG+a+n++++wkypslsk
   Q: 392  LIRCWSEHQGAVKALAWCPWQPNILASGGGTSDRHIRIWNVNSGSCISSLDTQSQISSLVFAPNYKELVSAHGYAHNNVVVWKYPSLSK 480
           778899*********************************************************************************** PP
   S: 260  vaelkgheaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           vael+gh+ Rvlsl+lspd ++++t+a+Det+r+wk f++++ k
   Q: 481  VAELNGHDDRVLSLTLSPDCSTVATVAADETIRLWKSFEMDPIK 524
           ***************************************98765 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MSALWHLNVV ASYARNSKSR ERREFVLPCI SRFLDEVYEN VDKMAQFGFE NDIHSILKLD 60
MPITNAPMAR WQRKASSSNT SALSGLSPGK SANVSLSSSK TPSKTPGKNK KQTPSKMGGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCGCTCTA ACGCATTCGT AAACGTTACC ATAGCAATGC GCCGAGCTAA CGGCAGCTGC 60
TTGAACTAAC CAATCGCATG AGCGCTCTGT GGCATTTAAA CGTCGTGGCG TCATACGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	43.82	3.00e-99	355.00
IUUC-Aml-001545	Ailuropoda melanoleuca	62.57	0.00e+00	635.00
IUUC-Atr-003103	Amborella trichopoda	43.31	5.00e-97	348.00
IUUC-Apl-003255	Anas platyrhynchos	65.15	2.00e-177	615.00
IUUC-Aca-004920	Anolis carolinensis	60.27	8.00e-180	623.00
IUUC-Aly-006253	Arabidopsis lyrata	45.71	4.00e-104	372.00
IUUC-Ath-006795	Arabidopsis thaliana	44.14	7.00e-105	374.00
IUUC-Ame-010850	Astyanax mexicanus	75.62	1.00e-117	416.00
IUUC-Bgr-012059	Blumeria graminis	46.63	8.00e-92	331.00
IUUC-Bta-012625	Bos taurus	62.97	0.00e+00	635.00
IUUC-Bci-013607	Botrytis cinerea	46.04	9.00e-93	334.00
IUUC-Bdi-014344	Brachypodium distachyon	44.34	3.00e-98	352.00
IUUC-Bol-015368	Brassica oleracea	44.94	5.00e-103	369.00
IUUC-Bra-016738	Brassica rapa	45.23	1.00e-101	363.00
IUUC-Cja-019132	Callithrix jacchus	62.57	0.00e+00	640.00
IUUC-Cfa-020780	Canis familiaris	62.57	0.00e+00	634.00
IUUC-Cpo-022223	Cavia porcellus	62.65	3.00e-171	595.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	46.49	8.00e-109	387.00
IUUC-Csa-023666	Chlorocebus sabaeus	62.77	0.00e+00	639.00
IUUC-Cho-024920	Choloepus hoffmanni	62.46	1.00e-101	363.00
IUUC-Cin-025675	Ciona intestinalis	48.24	2.00e-123	436.00
IUUC-Csv-026019	Ciona savignyi	48.41	2.00e-121	429.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	44.48	1.00e-91	330.00
IUUC-Cne-026872	Cryptococcus neoformans	44.55	9.00e-86	311.00
IUUC-Cme-027234	Cyanidioschyzon merolae	50.00	1.00e-99	357.00
IUUC-Dre-028026	Danio rerio	70.78	0.00e+00	736.00
IUUC-Dno-028865	Dasypus novemcinctus	60.28	2.00e-179	622.00
IUUC-Dor-030958	Dipodomys ordii	62.77	0.00e+00	627.00
IUUC-Dse-031391	Dothistroma septosporum	46.15	2.00e-92	333.00
IUUC-Dme-031905	Drosophila melanogaster	46.79	5.00e-129	454.00
IUUC-Ete-032387	Echinops telfairi	58.02	4.00e-172	597.00
IUUC-Eca-033522	Equus caballus	55.06	2.00e-159	555.00
IUUC-Eeu-035059	Erinaceus europaeus	55.07	9.00e-152	530.00
IUUC-Fca-036346	Felis catus	64.43	9.00e-167	580.00
IUUC-Fal-037558	Ficedula albicollis	62.45	0.00e+00	644.00
IUUC-Fox-037850	Fusarium oxysporum	44.48	3.00e-92	332.00
IUUC-Fso-038375	Fusarium solani	44.75	1.00e-92	334.00
IUUC-Gmo-039284	Gadus morhua	83.43	0.00e+00	827.00
IUUC-Ggr-039864	Gaeumannomyces graminis	43.56	1.00e-91	330.00
IUUC-Gga-040790	Gallus gallus	63.14	0.00e+00	652.00
IUUC-Gac-041431	Gasterosteus aculeatus	87.05	0.00e+00	865.00
IUUC-Gma-043985	Glycine max	45.94	3.00e-96	345.00
IUUC-Ggo-045052	Gorilla gorilla	62.97	0.00e+00	639.00
IUUC-Hsa-046305	Homo sapiens	62.97	0.00e+00	639.00
IUUC-Hvu-047476	Hordeum vulgare	43.69	3.00e-101	362.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	63.17	3.00e-172	598.00
IUUC-Lch-050174	Latimeria chalumnae	56.78	8.00e-154	536.00
IUUC-Lpe-050954	Leersia perrieri	44.90	1.00e-89	323.00
IUUC-Loc-052638	Lepisosteus oculatus	68.63	0.00e+00	679.00
IUUC-Lma-052998	Leptosphaeria maculans	44.06	6.00e-90	325.00
IUUC-Laf-053742	Loxodonta africana	61.98	0.00e+00	629.00
IUUC-Mcc-054948	Macaca mulatta	62.77	0.00e+00	639.00
IUUC-Meu-056013	Macropus eugenii	61.54	6.00e-99	354.00
IUUC-Mor-057277	Magnaporthe oryzae	42.59	2.00e-88	320.00
IUUC-Mpo-057624	Magnaporthe poae	43.65	3.00e-89	323.00
IUUC-Mtr-057725	Medicago truncatula	44.77	6.00e-97	347.00
IUUC-Mga-060102	Meleagris gallopavo	64.82	0.00e+00	656.00
IUUC-Mmr-061615	Microcebus murinus	63.99	0.00e+00	633.00
IUUC-Mdo-061982	Monodelphis domestica	62.14	5.00e-159	556.00
IUUC-Mmu-063864	Mus musculus	63.17	0.00e+00	631.00
IUUC-Mac-064861	Musa acuminata	42.62	4.00e-98	351.00
IUUC-Mpu-066502	Mustela putorius furo	61.98	0.00e+00	638.00
IUUC-Mlu-067277	Myotis lucifugus	58.78	1.00e-169	589.00
IUUC-Ncr-068951	Neurospora crassa	45.16	4.00e-90	325.00
IUUC-Nle-070149	Nomascus leucogenys	62.77	0.00e+00	632.00
IUUC-Opr-070778	Ochotona princeps	62.74	7.00e-127	447.00
IUUC-Oan-073677	Ornithorhynchus anatinus	55.21	5.00e-149	521.00
IUUC-Ocu-073797	Oryctolagus cuniculus	63.22	0.00e+00	635.00
IUUC-Oba-075946	Oryza barthii	45.26	2.00e-98	352.00
IUUC-Obr-076018	Oryza brachyantha	44.27	1.00e-98	353.00
IUUC-Ogl-077254	Oryza glaberrima	45.50	2.00e-90	326.00
IUUC-Ogu-078521	Oryza glumaepatula	46.19	3.00e-98	353.00
IUUC-Oin-079145	Oryza indica	45.26	2.00e-98	353.00
IUUC-Olo-080798	Oryza longistaminata	45.95	5.00e-98	352.00
IUUC-Ome-081186	Oryza meridionalis	45.24	3.00e-98	353.00
IUUC-Oni-082540	Oryza nivara	45.26	3.00e-98	352.00
IUUC-Opu-083901	Oryza punctata	45.50	3.00e-98	352.00
IUUC-Oru-084562	Oryza rufipogon	46.19	4.00e-98	352.00
IUUC-Osa-086094	Oryza sativa	45.50	4.00e-90	325.00
IUUC-Ola-086907	Oryzias latipes	87.25	0.00e+00	794.00
IUUC-Olu-087647	Ostreococcus lucimarinus	46.19	5.00e-105	374.00
IUUC-Oga-088184	Otolemur garnettii	61.66	1.00e-179	622.00
IUUC-Oar-090023	Ovis aries	60.83	1.00e-168	586.00
IUUC-Ptr-090935	Pan troglodytes	61.80	4.00e-170	591.00
IUUC-Pan-091845	Papio anubis	62.77	0.00e+00	639.00
IUUC-Psi-093188	Pelodiscus sinensis	63.37	0.00e+00	674.00
IUUC-Pma-094187	Petromyzon marinus	48.71	3.00e-137	482.00
IUUC-Pno-094809	Phaeosphaeria nodorum	40.00	2.00e-91	330.00
IUUC-Ppa-095457	Physcomitrella patens	44.62	2.00e-100	359.00
IUUC-Pfo-097429	Poecilia formosa	81.84	0.00e+00	758.00
IUUC-Pab-098603	Pongo abelii	62.77	0.00e+00	638.00
IUUC-Pop-098890	Populus trichocarpa	45.33	3.00e-100	358.00
IUUC-Pca-101062	Procavia capensis	62.50	0.00e+00	629.00
IUUC-Ppe-101865	Prunus persica	43.95	2.00e-91	329.00
IUUC-Pva-102925	Pteropus vampyrus	61.58	0.00e+00	634.00
IUUC-Pte-104142	Pyrenophora teres	45.93	3.00e-90	325.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	46.22	1.00e-90	327.00
IUUC-Rno-106005	Rattus norvegicus	62.97	0.00e+00	629.00
IUUC-Sha-107472	Sarcophilus harrisii	62.13	0.00e+00	629.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	39.68	2.00e-89	323.00
IUUC-Spo-108075	Schizosaccharomyces pombe	41.06	7.00e-93	334.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	46.33	1.00e-92	333.00
IUUC-Smo-108922	Selaginella moellendorffii	44.64	1.00e-109	389.00
IUUC-Sit-110732	Setaria italica	45.18	5.00e-98	351.00
IUUC-Sly-111025	Solanum lycopersicum	45.37	4.00e-92	332.00
IUUC-Stu-112676	Solanum tuberosum	45.12	1.00e-93	336.00
IUUC-Sar-113092	Sorex araneus	59.72	5.00e-166	577.00
IUUC-Sbi-114558	Sorghum bicolor	44.87	1.00e-97	350.00
IUUC-Ssc-115710	Sus scrofa	62.77	0.00e+00	634.00
IUUC-Tgu-117100	Taeniopygia guttata	62.45	0.00e+00	644.00
IUUC-Tru-118184	Takifugu rubripes	75.00	0.00e+00	647.00
IUUC-Tsy-118892	Tarsius syrichta	62.81	4.00e-103	367.00
IUUC-Tni-120474	Tetraodon nigroviridis	84.63	0.00e+00	793.00
IUUC-Tca-120949	Theobroma cacao	43.38	2.00e-100	359.00
IUUC-Tre-122211	Trichoderma reesei	38.49	3.00e-92	332.00
IUUC-Tvi-122531	Trichoderma virens	46.04	4.00e-91	329.00
IUUC-Tae-125122	Triticum aestivum	44.73	3.00e-93	335.00
IUUC-Tur-126018	Triticum urartu	44.81	8.00e-93	334.00
IUUC-Tme-126905	Tuber melanosporum	46.84	7.00e-91	328.00
IUUC-Tbe-127384	Tupaia belangeri	67.22	2.00e-124	439.00
IUUC-Ttr-128511	Tursiops truncatus	62.97	0.00e+00	635.00
IUUC-Vda-129993	Verticillium dahliae	45.75	1.00e-92	334.00
IUUC-Vpa-130775	Vicugna pacos	45.87	1.00e-73	270.00
IUUC-Vvi-131245	Vitis vinifera	43.63	3.00e-89	322.00
IUUC-Xtr-131993	Xenopus tropicalis	63.69	0.00e+00	667.00
IUUC-Xma-133332	Xiphophorus maculatus	85.74	0.00e+00	835.00
IUUC-Zma-135135	Zea mays	43.47	2.00e-95	343.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence