iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-042383

Ensembl Protein ID

ENSGACP00000024570.1

UniProt Accession

G3Q3W6; G3Q3W6_GASAC

Protein Name

Tyrosine-protein kinase

Gene Name

TXK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000018586.1	ENSGACT00000024619.1	ENSGACP00000024570.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.30e-12	47.1	73	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v ++yd++a++d +Ltlk+G+   ++  ++qd+ W++++ + +g +G++P+n+v++
   Q: 73   TVVAMYDFTAKEDTDLTLKQGEEYVIL--HKQDQLWWRAQ-DKHGNKGFIPSNYVTE 126
           6899*******************9999..9*********7.**************87 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MIHSNHSIHS VFCCCCSVQS REISTHVELE GSSSLCFGTR RYPGHACRGD RSRKKLPLPP 60
PDDEHAEGQG LLTVVAMYDF TAKEDTDLTL KQGEEYVILH KQDQLWWRAQ DKHGNKGFIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGTGAAGGC AACCGGAGAC ACGCTGACCT CGACGGAGCG GGAGAGGAAC ATGAAGAGGA 60
GCTGAAGAAG AAGAAGAGCG TCAACGCGAA GGCCGTCATG ATTCACTCAA GTAAGCAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001365	Ailuropoda melanoleuca	50.00	9.00e-128	450.00
IUUC-Apl-003669	Anas platyrhynchos	54.93	3.00e-132	465.00
IUUC-Aca-004978	Anolis carolinensis	47.79	3.00e-120	426.00
IUUC-Ame-010694	Astyanax mexicanus	56.67	7.00e-161	560.00
IUUC-Bta-012467	Bos taurus	50.00	7.00e-127	447.00
IUUC-Cja-018841	Callithrix jacchus	49.78	1.00e-127	449.00
IUUC-Cfa-020983	Canis familiaris	50.79	2.00e-126	446.00
IUUC-Cpo-021307	Cavia porcellus	50.44	2.00e-128	452.00
IUUC-Csa-023508	Chlorocebus sabaeus	50.57	8.00e-127	447.00
IUUC-Dre-028544	Danio rerio	61.98	2.00e-140	492.00
IUUC-Dno-029828	Dasypus novemcinctus	50.55	1.00e-128	454.00
IUUC-Dor-030102	Dipodomys ordii	50.22	4.00e-126	444.00
IUUC-Ete-032981	Echinops telfairi	41.70	8.00e-95	341.00
IUUC-Eca-033594	Equus caballus	50.00	3.00e-127	449.00
IUUC-Eeu-035281	Erinaceus europaeus	43.97	7.00e-74	271.00
IUUC-Fca-035495	Felis catus	51.02	6.00e-127	447.00
IUUC-Fal-036771	Ficedula albicollis	55.21	2.00e-132	466.00
IUUC-Gga-041193	Gallus gallus	49.24	2.00e-125	442.00
IUUC-Hsa-045931	Homo sapiens	50.57	5.00e-126	445.00
IUUC-Itr-048061	Ictidomys tridecemlineatus	50.00	4.00e-127	448.00
IUUC-Lch-050516	Latimeria chalumnae	57.46	2.00e-135	476.00
IUUC-Loc-052730	Lepisosteus oculatus	59.81	3.00e-176	611.00
IUUC-Laf-053516	Loxodonta africana	50.22	7.00e-128	451.00
IUUC-Mcc-054795	Macaca mulatta	50.57	4.00e-126	445.00
IUUC-Meu-056157	Macropus eugenii	51.44	1.00e-109	390.00
IUUC-Mga-060196	Meleagris gallopavo	55.63	2.00e-138	486.00
IUUC-Mmr-060824	Microcebus murinus	50.57	3.00e-126	445.00
IUUC-Mdo-062054	Monodelphis domestica	56.92	8.00e-141	494.00
IUUC-Mmu-064047	Mus musculus	50.65	4.00e-128	451.00
IUUC-Mpu-066786	Mustela putorius furo	56.03	6.00e-139	487.00
IUUC-Mlu-067671	Myotis lucifugus	49.56	1.00e-119	424.00
IUUC-Nle-069108	Nomascus leucogenys	50.57	4.00e-126	445.00
IUUC-Ont-072585	Oreochromis niloticus	72.36	0.00e+00	713.00
IUUC-Oan-073495	Ornithorhynchus anatinus	46.85	1.00e-128	453.00
IUUC-Ocu-074416	Oryctolagus cuniculus	50.22	7.00e-128	451.00
IUUC-Ola-086938	Oryzias latipes	72.50	2.00e-180	624.00
IUUC-Oga-088995	Otolemur garnettii	51.02	9.00e-127	447.00
IUUC-Oar-089632	Ovis aries	50.00	4.00e-127	448.00
IUUC-Ptr-090941	Pan troglodytes	50.57	3.00e-126	446.00
IUUC-Pan-091900	Papio anubis	48.98	1.00e-117	417.00
IUUC-Psi-093565	Pelodiscus sinensis	55.19	1.00e-134	473.00
IUUC-Pfo-096955	Poecilia formosa	73.26	0.00e+00	736.00
IUUC-Pab-097587	Pongo abelii	50.57	3.00e-126	445.00
IUUC-Pva-102583	Pteropus vampyrus	49.34	2.00e-119	422.00
IUUC-Rno-104868	Rattus norvegicus	49.24	7.00e-121	427.00
IUUC-Sha-106744	Sarcophilus harrisii	49.78	1.00e-127	450.00
IUUC-Sar-113041	Sorex araneus	51.65	2.00e-123	436.00
IUUC-Ssc-115294	Sus scrofa	50.00	2.00e-127	449.00
IUUC-Tgu-116458	Taeniopygia guttata	55.21	1.00e-135	476.00
IUUC-Tsy-118945	Tarsius syrichta	51.42	6.00e-121	427.00
IUUC-Ttr-128769	Tursiops truncatus	51.24	1.00e-115	410.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence