iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dse-031536

Ensembl Protein ID

EME40813

UniProt Accession

N1PDX9; N1PDX9_DOTSN

Genbank Protein ID

EME40813.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

KB446543

Gene Name

DOTSEDRAFT_90918

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
DOTSEDRAFT_90918	EME40813	EME40813

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.00e-56	192.3	23	389

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllv..GagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           YDRQ+rlwG+ +q +l+++++ll+  G g +G+E+lKnLvl G+g++ v+D   v  ++l+ +F++++ + gk +Ae + + l+elnpd ++ a +e+i++
   Q: 23   YDRQLRLWGAAGQIALEETHILLInnGSGVTGVETLKNLVLPGIGQFSVLDSGIVAEADLGVNFFLEDASLGKYRAEETVKLLQELNPDAKGHAITEPIET 123
           ************************555677*********************************************************************** PP
   S: 100  leeeivFfkkfdvVvlaldnrearrk.vnrlclnarvpliesgtlGllGqvrviikg.ltecyscsd....dppqktiPfctlketpn...........aa 183
            + ++  +k +++Vv+a     a ++ + +++  + +p++ + + G+++q +v++++ +++ + ++d     ++++ +P++ l ++             ++
   Q: 124  WASKEGALKPYTLVVVAAPVDPAILYnIQNAL--YGIPIFYIHSVGFYSQFSVSLPYdFPIVDTHPDptatTDLRLLKPWPALLDFAKrqtrsmdkmnaEE 222
           *99988********999888888766477777..9*********************8357777777799999**************665555555555588 PP
   S: 184  ehtiewavlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv......... 274
             +i++  l+ ++lee+++ + ++ ++d++ek+ ++d+v+s++++  eenf+ea ++++k++++ t +  + ++l+ +e   +++ ++pfw+         
   Q: 223  FAHIPYLCLLLHHLEEWKSTHGGKLPMDYKEKTVFRDLVRSGSVN--EENFDEACAAVLKSLNPPTPERgVLDILNAPEVHMISETSAPFWIianaimqfy 321
           8899999********************************988777..8******************9999******************************* PP
   S: 275  .............................sfcsnaealqvpekvekdeevvkasaplylllralerfekk 315
                                        + +  ++a +v ++v + e+ +++sa+  ++ + +e+f+k 
   Q: 322  qdhgelplpgavpdmkarsntyielqniyKAKAREDASEVLKTVRQTEQQLARSAA--IAEKEVENFCKG 389
           ***************99999999999999888888888899999999999988865..777777777765 PP

Organism

Dothistroma septosporum

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MANTQTEVPP PLQDVPTAKE RKYDRQLRLW GAAGQIALEE THILLINNGS GVTGVETLKN 60
LVLPGIGQFS VLDSGIVAEA DLGVNFFLED ASLGKYRAEE TVKLLQELNP DAKGHAITEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAACA CTCAGACCGA GGTGCCGCCT CCACTGCAGG ACGTGCCCAC CGCCAAAGAG 60
CGCAAGTACG ATCGCCAGTT GAGACTTTGG GTAGGTGGGT TGCTAGCAGC TATGAGGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	30.76	3.00e-66	244.00
IUUC-Aml-002333	Ailuropoda melanoleuca	35.35	4.00e-84	303.00
IUUC-Atr-002644	Amborella trichopoda	32.43	3.00e-59	221.00
IUUC-Apl-003446	Anas platyrhynchos	32.67	3.00e-72	264.00
IUUC-Aca-004450	Anolis carolinensis	32.15	3.00e-79	287.00
IUUC-Aly-005466	Arabidopsis lyrata	31.29	2.00e-66	244.00
IUUC-Ath-007600	Arabidopsis thaliana	33.27	5.00e-68	249.00
IUUC-Ago-007900	Ashbya gossypii	24.83	3.00e-22	97.80
IUUC-Acl-008333	Aspergillus clavatus	45.36	7.00e-128	449.00
IUUC-Afl-008529	Aspergillus flavus	45.79	1.00e-126	445.00
IUUC-Afu-009071	Aspergillus fumigatus	45.71	1.00e-129	455.00
IUUC-Ani-009443	Aspergillus nidulans	45.61	9.00e-129	452.00
IUUC-Ang-009669	Aspergillus niger	46.21	2.00e-132	464.00
IUUC-Aor-009914	Aspergillus oryzae	44.70	8.00e-125	439.00
IUUC-Ate-010450	Aspergillus terreus	46.86	7.00e-128	449.00
IUUC-Ame-011183	Astyanax mexicanus	34.21	1.00e-82	298.00
IUUC-Bgr-012111	Blumeria graminis	43.47	7.00e-115	405.00
IUUC-Bta-012583	Bos taurus	35.29	4.00e-85	306.00
IUUC-Bci-013892	Botrytis cinerea	51.70	1.00e-102	365.00
IUUC-Bdi-014592	Brachypodium distachyon	31.16	6.00e-64	236.00
IUUC-Bol-015487	Brassica oleracea	32.91	9.00e-72	262.00
IUUC-Bra-017506	Brassica rapa	32.97	5.00e-72	263.00
IUUC-Cel-018456	Caenorhabditis elegans	31.74	2.00e-64	238.00
IUUC-Cja-020007	Callithrix jacchus	35.11	3.00e-83	300.00
IUUC-Cfa-020324	Canis familiaris	35.47	9.00e-86	309.00
IUUC-Cpo-022248	Cavia porcellus	32.10	2.00e-43	168.00
IUUC-Csa-023149	Chlorocebus sabaeus	31.42	2.00e-58	218.00
IUUC-Cho-024537	Choloepus hoffmanni	28.14	1.00e-46	179.00
IUUC-Cin-025763	Ciona intestinalis	33.10	7.00e-74	269.00
IUUC-Csv-026113	Ciona savignyi	31.83	8.00e-71	259.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	40.64	3.00e-105	373.00
IUUC-Cne-026884	Cryptococcus neoformans	30.34	1.00e-58	219.00
IUUC-Dre-028140	Danio rerio	33.86	2.00e-84	304.00
IUUC-Dno-030033	Dasypus novemcinctus	35.60	3.00e-71	260.00
IUUC-Dor-030513	Dipodomys ordii	53.85	1.00e-25	109.00
IUUC-Dme-031683	Drosophila melanogaster	32.33	3.00e-70	257.00
IUUC-Ete-032420	Echinops telfairi	31.58	1.00e-65	241.00
IUUC-Eca-033992	Equus caballus	30.96	8.00e-56	209.00
IUUC-Eeu-034713	Erinaceus europaeus	55.45	9.00e-27	113.00
IUUC-Fca-036548	Felis catus	34.94	6.00e-83	299.00
IUUC-Fal-037600	Ficedula albicollis	32.55	7.00e-71	259.00
IUUC-Fox-038037	Fusarium oxysporum	43.03	6.00e-117	412.00
IUUC-Fso-038387	Fusarium solani	41.21	9.00e-114	402.00
IUUC-Gmo-038562	Gadus morhua	31.38	2.00e-77	281.00
IUUC-Ggr-040005	Gaeumannomyces graminis	47.51	2.00e-100	357.00
IUUC-Gga-041129	Gallus gallus	33.04	1.00e-76	278.00
IUUC-Gac-042558	Gasterosteus aculeatus	32.33	2.00e-76	278.00
IUUC-Gma-043221	Glycine max	31.88	8.00e-66	243.00
IUUC-Ggo-045611	Gorilla gorilla	35.28	7.00e-83	299.00
IUUC-Hsa-046563	Homo sapiens	35.47	2.00e-84	304.00
IUUC-Hvu-047790	Hordeum vulgare	27.95	2.00e-38	151.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	35.47	2.00e-85	307.00
IUUC-Kpa-049309	Komagataella pastoris	31.48	5.00e-66	243.00
IUUC-Lch-050038	Latimeria chalumnae	34.63	1.00e-75	275.00
IUUC-Lpe-051535	Leersia perrieri	28.87	5.00e-45	174.00
IUUC-Loc-051917	Lepisosteus oculatus	32.52	5.00e-70	256.00
IUUC-Lma-053112	Leptosphaeria maculans	52.99	3.00e-175	606.00
IUUC-Laf-053690	Loxodonta africana	34.94	8.00e-84	302.00
IUUC-Mcc-055117	Macaca mulatta	34.51	1.00e-79	288.00
IUUC-Meu-056761	Macropus eugenii	29.86	6.00e-56	209.00
IUUC-Mor-057230	Magnaporthe oryzae	41.68	3.00e-116	410.00
IUUC-Mpo-057514	Magnaporthe poae	42.78	5.00e-115	406.00
IUUC-Mtr-058551	Medicago truncatula	32.39	3.00e-64	237.00
IUUC-Mla-059183	Melampsora laricipopulina	34.25	1.00e-80	292.00
IUUC-Mga-060144	Meleagris gallopavo	32.20	5.00e-73	266.00
IUUC-Mvi-060221	Microbotryum violaceum	35.35	8.00e-60	223.00
IUUC-Mmr-061325	Microcebus murinus	34.40	3.00e-78	284.00
IUUC-Mdo-062532	Monodelphis domestica	35.12	1.00e-82	298.00
IUUC-Mmu-063956	Mus musculus	35.12	2.00e-85	308.00
IUUC-Mac-064521	Musa acuminata	31.35	1.00e-64	239.00
IUUC-Mpu-066716	Mustela putorius furo	34.10	1.00e-72	266.00
IUUC-Mlu-067459	Myotis lucifugus	34.97	4.00e-85	306.00
IUUC-Nfi-068245	Neosartorya fischeri	45.38	6.00e-129	452.00
IUUC-Ncr-068910	Neurospora crassa	44.62	1.00e-126	444.00
IUUC-Nle-070034	Nomascus leucogenys	33.88	9.00e-76	275.00
IUUC-Opr-070552	Ochotona princeps	31.94	1.00e-62	232.00
IUUC-Ont-071426	Oreochromis niloticus	32.21	2.00e-78	285.00
IUUC-Oan-073389	Ornithorhynchus anatinus	29.50	7.00e-49	186.00
IUUC-Ocu-074911	Oryctolagus cuniculus	34.94	4.00e-84	303.00
IUUC-Oba-075437	Oryza barthii	30.13	8.00e-53	199.00
IUUC-Obr-076684	Oryza brachyantha	30.07	3.00e-51	194.00
IUUC-Ogl-077170	Oryza glaberrima	30.13	8.00e-53	199.00
IUUC-Ogu-078844	Oryza glumaepatula	29.68	4.00e-46	177.00
IUUC-Oin-079105	Oryza indica	30.13	6.00e-53	199.00
IUUC-Olo-080943	Oryza longistaminata	28.60	2.00e-39	155.00
IUUC-Oni-082891	Oryza nivara	29.22	7.00e-47	179.00
IUUC-Opu-083457	Oryza punctata	30.31	4.00e-52	197.00
IUUC-Oru-084960	Oryza rufipogon	28.60	1.00e-39	155.00
IUUC-Osa-085358	Oryza sativa	29.76	1.00e-52	198.00
IUUC-Ola-086420	Oryzias latipes	31.76	7.00e-49	186.00
IUUC-Olu-087625	Ostreococcus lucimarinus	25.70	5.00e-42	164.00
IUUC-Oga-088810	Otolemur garnettii	34.94	2.00e-84	304.00
IUUC-Oar-089196	Ovis aries	34.93	3.00e-83	300.00
IUUC-Ptr-090617	Pan troglodytes	35.29	1.00e-83	301.00
IUUC-Pan-092761	Papio anubis	35.29	3.00e-85	307.00
IUUC-Psi-093191	Pelodiscus sinensis	30.98	5.00e-71	259.00
IUUC-Pma-094380	Petromyzon marinus	34.27	1.00e-71	261.00
IUUC-Pno-095084	Phaeosphaeria nodorum	50.53	2.00e-155	542.00
IUUC-Ppa-095798	Physcomitrella patens	30.86	2.00e-63	234.00
IUUC-Pfo-096467	Poecilia formosa	32.51	6.00e-77	279.00
IUUC-Pab-098255	Pongo abelii	36.05	5.00e-72	263.00
IUUC-Pop-099871	Populus trichocarpa	31.40	5.00e-66	243.00
IUUC-Pca-100807	Procavia capensis	37.44	3.00e-29	121.00
IUUC-Ppe-101280	Prunus persica	31.29	9.00e-66	242.00
IUUC-Pva-102333	Pteropus vampyrus	34.64	6.00e-79	286.00
IUUC-Pgr-103661	Puccinia graminis	31.15	4.00e-66	243.00
IUUC-Ptt-103889	Puccinia triticina	29.35	9.00e-62	229.00
IUUC-Pte-104355	Pyrenophora teres	55.46	0.00e+00	629.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	55.46	3.00e-180	623.00
IUUC-Rno-105810	Rattus norvegicus	34.40	2.00e-82	298.00
IUUC-Sce-106397	Saccharomyces cerevisiae	25.23	1.00e-23	102.00
IUUC-Sha-106770	Sarcophilus harrisii	38.91	2.00e-48	183.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	29.50	3.00e-63	234.00
IUUC-Spo-108276	Schizosaccharomyces pombe	31.06	3.00e-69	254.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	45.90	3.00e-126	443.00
IUUC-Smo-109213	Selaginella moellendorffii	34.59	4.00e-75	273.00
IUUC-Sit-110157	Setaria italica	31.47	4.00e-65	240.00
IUUC-Sly-111105	Solanum lycopersicum	30.91	2.00e-67	248.00
IUUC-Stu-112469	Solanum tuberosum	30.91	1.00e-66	245.00
IUUC-Sar-113083	Sorex araneus	28.88	4.00e-25	107.00
IUUC-Sbi-113813	Sorghum bicolor	30.85	1.00e-65	242.00
IUUC-Sre-115058	Sporisorium reilianum	31.83	2.00e-71	261.00
IUUC-Tgu-116772	Taeniopygia guttata	32.92	1.00e-74	271.00
IUUC-Tru-118686	Takifugu rubripes	31.32	3.00e-77	280.00
IUUC-Tsy-119111	Tarsius syrichta	35.25	2.00e-38	151.00
IUUC-Tni-120231	Tetraodon nigroviridis	29.23	5.00e-63	233.00
IUUC-Tca-121491	Theobroma cacao	30.81	2.00e-61	228.00
IUUC-Tre-122103	Trichoderma reesei	41.88	6.00e-113	399.00
IUUC-Tvi-122672	Trichoderma virens	47.46	2.00e-96	344.00
IUUC-Tae-125316	Triticum aestivum	30.80	3.00e-66	244.00
IUUC-Tur-126487	Triticum urartu	29.76	2.00e-61	228.00
IUUC-Tme-127097	Tuber melanosporum	39.93	4.00e-96	343.00
IUUC-Ttr-128465	Tursiops truncatus	31.91	8.00e-67	246.00
IUUC-Uma-129645	Ustilago maydis	33.61	1.00e-71	262.00
IUUC-Vda-129989	Verticillium dahliae	37.57	1.00e-83	301.00
IUUC-Vpa-130529	Vicugna pacos	32.80	2.00e-71	261.00
IUUC-Vvi-131059	Vitis vinifera	31.35	3.00e-64	237.00
IUUC-Xtr-132002	Xenopus tropicalis	35.12	1.00e-86	311.00
IUUC-Xma-133930	Xiphophorus maculatus	32.45	1.00e-76	278.00
IUUC-Yli-134505	Yarrowia lipolytica	33.87	1.00e-69	255.00
IUUC-Zma-135895	Zea mays	31.22	9.00e-66	242.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence