iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002177.1	ENSSHAT00000002485.1	ENSSHAP00000002459.1
ENSSHAG00000002177.1	ENSSHAT00000002486.1	ENSSHAP00000002460.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-08	35.1	13	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle f++ p+++pCgH f+  Cl + w     ++  +f CP Cr
   Q: 13   CSICLEIFQE-PVTTPCGHNFCSRCLdETW----TVQDSQFFCPQCR 54
           ********99.*******************....99999999****8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MAELQPLTDE LTCSICLEIF QEPVTTPCGH NFCSRCLDET WTVQDSQFFC PQCRTCFQMR 60
PQLKKNTVLC AVVEQVQQAH SLWDLGASNS ESQDGEPLYP SSRKGSQAKE EPTKTVACDH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTATTTTTA TTTTCGCCTT TCTGTGTATT CCGGGTATTT AGTACACCGC CTGGTACATA 60
GTAGGTGTTT AATAAATGTT CGTTGGTTTC GCTAGTGTTA AATGAAATAT AACAGTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

KEGG

shr:100928651

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	52.88	0.00e+00	681.00
IUUC-Apl-004101	Anas platyrhynchos	43.64	2.00e-148	519.00
IUUC-Aca-005025	Anolis carolinensis	46.93	7.00e-177	613.00
IUUC-Bta-012735	Bos taurus	54.52	0.00e+00	716.00
IUUC-Cja-019996	Callithrix jacchus	52.94	2.00e-113	402.00
IUUC-Cfa-020466	Canis familiaris	54.34	0.00e+00	715.00
IUUC-Cpo-021737	Cavia porcellus	51.78	0.00e+00	670.00
IUUC-Csa-023217	Chlorocebus sabaeus	53.12	0.00e+00	689.00
IUUC-Cho-024346	Choloepus hoffmanni	41.99	2.00e-57	216.00
IUUC-Dno-030082	Dasypus novemcinctus	51.11	0.00e+00	637.00
IUUC-Dor-030335	Dipodomys ordii	38.53	2.00e-87	316.00
IUUC-Ete-032923	Echinops telfairi	50.71	9.00e-176	609.00
IUUC-Eca-033411	Equus caballus	54.95	0.00e+00	711.00
IUUC-Eeu-034656	Erinaceus europaeus	53.00	8.00e-112	397.00
IUUC-Fca-035371	Felis catus	54.95	0.00e+00	713.00
IUUC-Fal-037008	Ficedula albicollis	44.96	1.00e-160	559.00
IUUC-Gmo-038730	Gadus morhua	37.74	2.00e-56	213.00
IUUC-Gga-040608	Gallus gallus	46.19	2.00e-160	558.00
IUUC-Gac-041409	Gasterosteus aculeatus	35.80	1.00e-113	404.00
IUUC-Ggo-044518	Gorilla gorilla	53.80	0.00e+00	680.00
IUUC-Hsa-045828	Homo sapiens	54.17	0.00e+00	698.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	49.23	2.00e-102	365.00
IUUC-Lch-050478	Latimeria chalumnae	39.59	3.00e-138	485.00
IUUC-Loc-052864	Lepisosteus oculatus	36.32	1.00e-113	403.00
IUUC-Laf-054325	Loxodonta africana	56.50	2.00e-120	425.00
IUUC-Mcc-054920	Macaca mulatta	52.83	0.00e+00	687.00
IUUC-Meu-056367	Macropus eugenii	82.86	2.00e-84	306.00
IUUC-Mga-059975	Meleagris gallopavo	46.68	1.00e-162	566.00
IUUC-Mmr-060748	Microcebus murinus	54.53	0.00e+00	709.00
IUUC-Mdo-062904	Monodelphis domestica	70.12	0.00e+00	857.00
IUUC-Mmu-063891	Mus musculus	52.90	0.00e+00	706.00
IUUC-Mpu-066473	Mustela putorius furo	55.00	0.00e+00	714.00
IUUC-Mlu-068185	Myotis lucifugus	52.49	0.00e+00	684.00
IUUC-Nle-070177	Nomascus leucogenys	53.71	0.00e+00	687.00
IUUC-Opr-070558	Ochotona princeps	42.20	1.00e-103	369.00
IUUC-Ont-071368	Oreochromis niloticus	37.47	4.00e-60	225.00
IUUC-Ocu-074461	Oryctolagus cuniculus	54.21	1.00e-116	413.00
IUUC-Ola-086556	Oryzias latipes	26.62	6.00e-55	208.00
IUUC-Oga-088937	Otolemur garnettii	51.04	0.00e+00	664.00
IUUC-Oar-089781	Ovis aries	53.40	2.00e-137	481.00
IUUC-Ptr-090771	Pan troglodytes	54.02	0.00e+00	685.00
IUUC-Pan-092830	Papio anubis	52.98	0.00e+00	689.00
IUUC-Psi-093664	Pelodiscus sinensis	47.62	3.00e-170	592.00
IUUC-Pma-094147	Petromyzon marinus	25.14	3.00e-59	223.00
IUUC-Ppa-095897	Physcomitrella patens	51.92	2.00e-09	56.60
IUUC-Pfo-096528	Poecilia formosa	35.18	7.00e-117	414.00
IUUC-Pab-097588	Pongo abelii	54.01	0.00e+00	681.00
IUUC-Pca-100890	Procavia capensis	55.59	4.00e-113	401.00
IUUC-Pva-102314	Pteropus vampyrus	54.89	0.00e+00	686.00
IUUC-Rno-105234	Rattus norvegicus	57.22	3.00e-114	405.00
IUUC-Sce-106362	Saccharomyces cerevisiae	42.86	4.00e-09	55.80
IUUC-Sar-113283	Sorex araneus	49.15	1.00e-87	316.00
IUUC-Ssc-115878	Sus scrofa	57.44	1.00e-74	272.00
IUUC-Tgu-117026	Taeniopygia guttata	61.17	3.00e-70	259.00
IUUC-Tru-117794	Takifugu rubripes	34.56	9.00e-98	350.00
IUUC-Tbe-127580	Tupaia belangeri	52.66	1.00e-99	355.00
IUUC-Ttr-128648	Tursiops truncatus	47.78	2.00e-113	402.00
IUUC-Vpa-130254	Vicugna pacos	72.73	6.00e-79	287.00
IUUC-Xtr-132892	Xenopus tropicalis	41.11	4.00e-73	268.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence