iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068238

Ensembl Protein ID

ENSMLUP00000013450.2

UniProt Accession

G1PQS1; G1PQS1_MYOLU

Genbank Protein ID

ENSMLUP00000013450

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02006273

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000014771.2	ENSMLUT00000014782.2	ENSMLUP00000013450.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-08	33.4	322	350

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf.sd.tllvsGsdDgtikvWD 29
           +++v+ ++  +d +++v+G+ Dgti  + 
   Q: 322  NSWVWTCKVkPDsNYVVVGCQDGTISFYQ 350
           799999999*999************8775 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MRAVLTWRDK AEQCIYDLAF KPDGNQLILA AGNRLLVSFF PPPVLLKKGK GRKTSHYFLI 60
EILLGKRFAS GSADKSVIIW TSKLEGILKY THNDSIQSVS YNPATHQLLA SCSSNDFGLW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGGCCG TCTTGACGTG GAGAGATAAA GCCGAACAGT GGTGAGGAGC GGGGCATTCC 60
GGGAGGAACG GGAGGCCCAG CCCCGGCGGG GATGGCGGTA GCCTTGGCGA GAACTCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	91.95	0.00e+00	2242.00
IUUC-Apl-003504	Anas platyrhynchos	74.47	0.00e+00	1828.00
IUUC-Aca-004767	Anolis carolinensis	81.80	0.00e+00	2039.00
IUUC-Ame-011642	Astyanax mexicanus	72.71	0.00e+00	1847.00
IUUC-Bta-012969	Bos taurus	89.94	0.00e+00	2180.00
IUUC-Cel-018670	Caenorhabditis elegans	38.38	0.00e+00	865.00
IUUC-Cja-019249	Callithrix jacchus	83.82	0.00e+00	2044.00
IUUC-Cfa-020915	Canis familiaris	92.28	0.00e+00	2208.00
IUUC-Cpo-021888	Cavia porcellus	74.58	0.00e+00	1860.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	47.53	0.00e+00	1075.00
IUUC-Csa-023533	Chlorocebus sabaeus	89.29	0.00e+00	2185.00
IUUC-Cin-025121	Ciona intestinalis	56.46	0.00e+00	1439.00
IUUC-Csv-026240	Ciona savignyi	56.73	0.00e+00	1367.00
IUUC-Dno-029685	Dasypus novemcinctus	85.35	0.00e+00	2070.00
IUUC-Dme-032005	Drosophila melanogaster	24.68	8.00e-08	53.10
IUUC-Ete-032682	Echinops telfairi	83.30	0.00e+00	1663.00
IUUC-Eca-033831	Equus caballus	93.00	0.00e+00	2299.00
IUUC-Eeu-034919	Erinaceus europaeus	84.17	0.00e+00	991.00
IUUC-Fca-036559	Felis catus	92.02	0.00e+00	2269.00
IUUC-Fal-037340	Ficedula albicollis	77.89	0.00e+00	1911.00
IUUC-Gmo-038607	Gadus morhua	22.81	1.00e-06	49.30
IUUC-Gga-040595	Gallus gallus	86.66	0.00e+00	1796.00
IUUC-Gac-041560	Gasterosteus aculeatus	24.07	5.00e-08	53.90
IUUC-Ggo-045356	Gorilla gorilla	85.52	0.00e+00	2155.00
IUUC-Hsa-046135	Homo sapiens	85.61	0.00e+00	2156.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	79.25	0.00e+00	1883.00
IUUC-Lch-050183	Latimeria chalumnae	80.66	0.00e+00	1164.00
IUUC-Loc-052049	Lepisosteus oculatus	76.08	0.00e+00	1905.00
IUUC-Laf-053728	Loxodonta africana	91.55	0.00e+00	2268.00
IUUC-Mcc-054971	Macaca mulatta	86.45	0.00e+00	2170.00
IUUC-Meu-056446	Macropus eugenii	81.93	0.00e+00	2074.00
IUUC-Mga-059296	Meleagris gallopavo	78.11	0.00e+00	1999.00
IUUC-Mmr-061232	Microcebus murinus	87.69	0.00e+00	2153.00
IUUC-Mdo-062115	Monodelphis domestica	89.72	0.00e+00	2226.00
IUUC-Mmu-063664	Mus musculus	89.76	0.00e+00	2256.00
IUUC-Mpu-066136	Mustela putorius furo	88.43	0.00e+00	2174.00
IUUC-Nle-069003	Nomascus leucogenys	85.61	0.00e+00	2075.00
IUUC-Ont-072080	Oreochromis niloticus	73.60	0.00e+00	1867.00
IUUC-Oan-072891	Ornithorhynchus anatinus	81.77	0.00e+00	892.00
IUUC-Ocu-074262	Oryctolagus cuniculus	90.73	0.00e+00	2220.00
IUUC-Ola-086538	Oryzias latipes	70.38	0.00e+00	1764.00
IUUC-Oga-088722	Otolemur garnettii	86.83	0.00e+00	2120.00
IUUC-Oar-089249	Ovis aries	92.45	0.00e+00	1870.00
IUUC-Ptr-090752	Pan troglodytes	90.18	0.00e+00	2050.00
IUUC-Pan-092472	Papio anubis	89.38	0.00e+00	2191.00
IUUC-Psi-093335	Pelodiscus sinensis	80.48	0.00e+00	2000.00
IUUC-Pma-094520	Petromyzon marinus	69.33	0.00e+00	1461.00
IUUC-Ppa-095600	Physcomitrella patens	48.67	1.00e-24	105.00
IUUC-Pfo-096526	Poecilia formosa	70.24	0.00e+00	1739.00
IUUC-Pab-098428	Pongo abelii	87.34	0.00e+00	1083.00
IUUC-Pca-100233	Procavia capensis	69.63	0.00e+00	937.00
IUUC-Pva-103064	Pteropus vampyrus	80.57	0.00e+00	1953.00
IUUC-Rno-105764	Rattus norvegicus	90.08	0.00e+00	2229.00
IUUC-Sha-106649	Sarcophilus harrisii	89.46	0.00e+00	2202.00
IUUC-Smo-109287	Selaginella moellendorffii	38.91	0.00e+00	825.00
IUUC-Tgu-116870	Taeniopygia guttata	80.48	0.00e+00	1943.00
IUUC-Tru-118661	Takifugu rubripes	69.24	0.00e+00	1737.00
IUUC-Tsy-119640	Tarsius syrichta	91.04	1.00e-109	391.00
IUUC-Tni-120812	Tetraodon nigroviridis	70.34	0.00e+00	1744.00
IUUC-Ttr-128862	Tursiops truncatus	88.45	0.00e+00	2234.00
IUUC-Vpa-130049	Vicugna pacos	86.49	7.00e-155	541.00
IUUC-Xtr-131914	Xenopus tropicalis	76.03	0.00e+00	1910.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence