iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062345

UUCD1 version

UUC-MoD-00185

Ensembl Protein ID

ENSMODP00000000916.3

UniProt Accession

F6SSV5; F6SSV5_MONDO

Protein Name

Uncharacterized protein

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000765.3	ENSMODT00000000934.3	ENSMODP00000000916.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	87.28	0.00e+00	869.00	IUUC-Hsa-045784
E3 activity/RING/RING	25.97	2.00e-28	122.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPEVFKKIKE 60
LYETRYAKKS SDPVQPHRPL DPLSIHSSYD RGSTVPRTSI STANIDYPVL YGKYLNGLGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG AGCTGGTGGA GGCCAAAGTA AGTGAGCAAG AGGTTCGGGG GGGGGGGGGG 60
CGGGACGCGG GGCTGCCTGG AGGCAGGCGC GAAAGGAGGC TGGTCGGGGG GGAGCGGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

KEGG

mdo:100022245

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	85.29	0.00e+00	845.00
IUUC-Apl-003765	Anas platyrhynchos	88.57	0.00e+00	863.00
IUUC-Ame-010763	Astyanax mexicanus	56.59	2.00e-146	512.00
IUUC-Bta-012369	Bos taurus	87.55	0.00e+00	873.00
IUUC-Cja-019450	Callithrix jacchus	86.27	0.00e+00	860.00
IUUC-Cfa-020933	Canis familiaris	87.21	0.00e+00	865.00
IUUC-Cpo-022112	Cavia porcellus	87.34	0.00e+00	838.00
IUUC-Csa-023913	Chlorocebus sabaeus	75.73	0.00e+00	696.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	27.05	4.00e-32	132.00
IUUC-Dre-027609	Danio rerio	55.41	2.00e-142	498.00
IUUC-Dno-029664	Dasypus novemcinctus	70.27	3.00e-151	528.00
IUUC-Ete-032988	Echinops telfairi	87.07	1.00e-163	569.00
IUUC-Eca-034430	Equus caballus	85.13	0.00e+00	834.00
IUUC-Fca-035968	Felis catus	91.78	1.00e-159	555.00
IUUC-Fal-037449	Ficedula albicollis	88.14	0.00e+00	844.00
IUUC-Gmo-038925	Gadus morhua	60.69	4.00e-139	488.00
IUUC-Gga-040362	Gallus gallus	91.53	0.00e+00	893.00
IUUC-Gac-042353	Gasterosteus aculeatus	58.73	2.00e-132	465.00
IUUC-Ggo-044810	Gorilla gorilla	84.93	0.00e+00	823.00
IUUC-Hsa-045784	Homo sapiens	87.28	0.00e+00	868.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	84.98	0.00e+00	847.00
IUUC-Lch-049727	Latimeria chalumnae	72.27	2.00e-151	528.00
IUUC-Loc-052354	Lepisosteus oculatus	52.96	7.00e-128	450.00
IUUC-Laf-054261	Loxodonta africana	86.63	0.00e+00	873.00
IUUC-Mcc-054931	Macaca mulatta	87.08	0.00e+00	858.00
IUUC-Meu-056468	Macropus eugenii	98.79	0.00e+00	946.00
IUUC-Mga-059981	Meleagris gallopavo	91.41	0.00e+00	721.00
IUUC-Mvi-060421	Microbotryum violaceum	29.07	9.00e-30	125.00
IUUC-Mmr-061181	Microcebus murinus	84.02	0.00e+00	813.00
IUUC-Mmu-063197	Mus musculus	81.78	0.00e+00	813.00
IUUC-Mpu-066275	Mustela putorius furo	85.83	0.00e+00	858.00
IUUC-Mlu-067194	Myotis lucifugus	87.40	0.00e+00	869.00
IUUC-Ont-072227	Oreochromis niloticus	59.18	7.00e-139	487.00
IUUC-Ola-086865	Oryzias latipes	56.95	2.00e-137	482.00
IUUC-Oga-088945	Otolemur garnettii	87.50	0.00e+00	871.00
IUUC-Oar-089412	Ovis aries	84.80	0.00e+00	832.00
IUUC-Ptr-091550	Pan troglodytes	80.79	3.00e-176	610.00
IUUC-Pan-092183	Papio anubis	87.28	0.00e+00	869.00
IUUC-Psi-093003	Pelodiscus sinensis	90.12	0.00e+00	876.00
IUUC-Pfo-096704	Poecilia formosa	58.33	5.00e-140	491.00
IUUC-Pab-097923	Pongo abelii	92.91	0.00e+00	736.00
IUUC-Pca-100249	Procavia capensis	71.70	3.00e-141	494.00
IUUC-Pva-102562	Pteropus vampyrus	82.77	0.00e+00	804.00
IUUC-Rno-105762	Rattus norvegicus	81.59	0.00e+00	818.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	1.00e-28	121.00
IUUC-Sha-107253	Sarcophilus harrisii	98.58	0.00e+00	939.00
IUUC-Sar-113149	Sorex araneus	83.90	6.00e-127	447.00
IUUC-Ssc-115241	Sus scrofa	87.74	0.00e+00	879.00
IUUC-Tgu-116884	Taeniopygia guttata	84.69	0.00e+00	826.00
IUUC-Tru-118031	Takifugu rubripes	59.18	6.00e-144	504.00
IUUC-Tni-119766	Tetraodon nigroviridis	56.18	2.00e-141	495.00
IUUC-Ttr-128556	Tursiops truncatus	79.96	0.00e+00	714.00
IUUC-Xtr-131866	Xenopus tropicalis	80.00	0.00e+00	788.00
IUUC-Xma-133963	Xiphophorus maculatus	58.14	4.00e-133	468.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence