iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059666

UUCD1 version

UUC-MeG-00594

Ensembl Protein ID

ENSMGAP00000013734.2

UniProt Accession

G1NK23; G1NK23_MELGA

Protein Name

Uncharacterized protein

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000013011.2	ENSMGAT00000014649.2	ENSMGAP00000013734.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-58	192.3	42	80
UBD/Beta-Prp	7.70e-125	415.7	663	877

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           Ht ++ claf  d  +lvs + D  +t+ vWD+r+g+ll
   Q: 42   HTHGIACLAFdLDgQRLVSVGLDskNTVCVWDWRKGKLL 80
           99*********66699*****9999***********987 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd++i +wd++t k l+ l   h+ +v av+fs dgk l++++ D  +ti +wd ++g+ +++++g
   Q: 663  HDDDILCLAIHPLKDYVATGqvGRDSSIHIWDTETIKPLSVLkGYHQYGVCAVDFSADGKRLASVGIDdnHTIVLWDWKKGEKLSAVRG 751
           4555566************96669******************5559******************9999999****************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
            +d++  ++++p+   ++++   + ++ w    g  +         g+ ++ +c+v+  ++ + +sG+  + v +W  +  +l++t + 
   Q: 752  SKDKIFVVKINPYMPEKLITVGIKHLKFWRRAGGGLIGRkgciGAMGRADTMMCAVYGWTEEMAFSGTSTGDVCIW--RDVFLIKTVKA 838
           ************9987788888*******87777777668887899******************************..889******98 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            h+++v s+   +  k +v+g++dg v lwd   ++c++t+ 
   Q: 839  -HDGPVFSMHALE--KGFVTGGKDGVVALWDDTFERCLKTYA 877
           .********9888..67**********************996 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

IGSLALHPER VLVATGQVGK EPYICVWDSY TVQTVSVLKD VHTHGIACLA FDLDGQRLVS 60
VGLDSKNTVC VWDWRKGKLL SMAPGHTDRI FDISWDLYQP NKLVSCGVKH IKFWSLCGNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGGCAGCC TTGCTTTGCA TCCTGAACGT GTGTTGGTGG CAACAGGTCA AGTTGGAAAG 60
GAACCATATA TCTGCGTATG GGACTCGTAC ACTGTGCAAA CTGTATCTGT TCTGAAGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	89.83	0.00e+00	3541.00
IUUC-Apl-003360	Anas platyrhynchos	97.39	0.00e+00	3716.00
IUUC-Ame-011681	Astyanax mexicanus	85.86	0.00e+00	3409.00
IUUC-Bta-012838	Bos taurus	89.27	0.00e+00	3522.00
IUUC-Cja-019068	Callithrix jacchus	89.68	0.00e+00	3513.00
IUUC-Cfa-020531	Canis familiaris	89.62	0.00e+00	3550.00
IUUC-Cpo-022304	Cavia porcellus	86.95	0.00e+00	3424.00
IUUC-Csa-023621	Chlorocebus sabaeus	89.02	0.00e+00	3311.00
IUUC-Cho-024944	Choloepus hoffmanni	72.08	0.00e+00	1425.00
IUUC-Dre-028772	Danio rerio	85.87	0.00e+00	3409.00
IUUC-Dno-030063	Dasypus novemcinctus	89.24	0.00e+00	3484.00
IUUC-Dor-030980	Dipodomys ordii	81.70	0.00e+00	1518.00
IUUC-Ete-032554	Echinops telfairi	90.16	0.00e+00	1026.00
IUUC-Eca-033909	Equus caballus	90.11	0.00e+00	3378.00
IUUC-Eeu-035180	Erinaceus europaeus	74.42	0.00e+00	1397.00
IUUC-Fal-037219	Ficedula albicollis	97.08	0.00e+00	3711.00
IUUC-Gmo-039146	Gadus morhua	81.35	0.00e+00	3216.00
IUUC-Gga-041095	Gallus gallus	97.11	0.00e+00	2625.00
IUUC-Gac-041341	Gasterosteus aculeatus	83.80	0.00e+00	3290.00
IUUC-Hsa-045997	Homo sapiens	89.94	0.00e+00	3521.00
IUUC-Lch-050306	Latimeria chalumnae	85.67	0.00e+00	3206.00
IUUC-Loc-052215	Lepisosteus oculatus	87.05	0.00e+00	3479.00
IUUC-Laf-054044	Loxodonta africana	88.65	0.00e+00	3492.00
IUUC-Mcc-054733	Macaca mulatta	89.94	0.00e+00	3515.00
IUUC-Meu-055977	Macropus eugenii	78.75	0.00e+00	920.00
IUUC-Mmr-060995	Microcebus murinus	89.99	0.00e+00	3511.00
IUUC-Mdo-062482	Monodelphis domestica	91.45	0.00e+00	3590.00
IUUC-Mmu-063533	Mus musculus	89.00	0.00e+00	3465.00
IUUC-Mpu-066704	Mustela putorius furo	89.62	0.00e+00	3534.00
IUUC-Mlu-067592	Myotis lucifugus	89.16	0.00e+00	3495.00
IUUC-Nle-069911	Nomascus leucogenys	89.57	0.00e+00	3503.00
IUUC-Ont-071966	Oreochromis niloticus	85.38	0.00e+00	3402.00
IUUC-Ola-086738	Oryzias latipes	84.61	0.00e+00	3347.00
IUUC-Oga-088436	Otolemur garnettii	87.49	0.00e+00	3433.00
IUUC-Oar-090153	Ovis aries	89.42	0.00e+00	3519.00
IUUC-Ptr-091008	Pan troglodytes	89.63	0.00e+00	3497.00
IUUC-Pan-092404	Papio anubis	89.62	0.00e+00	3502.00
IUUC-Psi-093417	Pelodiscus sinensis	94.32	0.00e+00	3629.00
IUUC-Pfo-096073	Poecilia formosa	85.40	0.00e+00	3406.00
IUUC-Pab-097900	Pongo abelii	89.36	0.00e+00	3501.00
IUUC-Pca-100107	Procavia capensis	75.77	0.00e+00	2413.00
IUUC-Pva-102880	Pteropus vampyrus	86.01	0.00e+00	3312.00
IUUC-Rno-106084	Rattus norvegicus	89.21	0.00e+00	3528.00
IUUC-Sha-106974	Sarcophilus harrisii	91.40	0.00e+00	3575.00
IUUC-Sar-113401	Sorex araneus	79.83	0.00e+00	1745.00
IUUC-Ssc-116057	Sus scrofa	89.34	0.00e+00	3563.00
IUUC-Tru-118444	Takifugu rubripes	84.45	0.00e+00	3326.00
IUUC-Tsy-118941	Tarsius syrichta	81.30	0.00e+00	2417.00
IUUC-Tni-120683	Tetraodon nigroviridis	83.99	0.00e+00	3295.00
IUUC-Tbe-127467	Tupaia belangeri	83.30	0.00e+00	1766.00
IUUC-Ttr-129138	Tursiops truncatus	85.69	0.00e+00	3335.00
IUUC-Vpa-130083	Vicugna pacos	84.02	0.00e+00	3240.00
IUUC-Xtr-131835	Xenopus tropicalis	89.39	0.00e+00	3543.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence