iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118444

UUCD1 version

UUC-TaR-01002

Ensembl Protein ID

ENSTRUP00000046763.1

UniProt Accession

H2VC20; H2VC20_TAKRU

Protein Name

Uncharacterized protein

Gene Name

si:dkey-1f12.3; eml5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000018277.1	ENSTRUT00000046921.1	ENSTRUP00000046763.1
ENSTRUG00000018277.1	ENSTRUT00000046922.1	ENSTRUP00000046764.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-60	198.6	236	264
UBD/Beta-Prp	6.00e-131	437.3	723	938

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDl 30
           H +++++++  +  +++G++Dg +++WDl
   Q: 236  HGSGIFSMNVCEEGFATGGRDGCVRLWDL 264
           899999999833338*************8 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrslsg.heaevtavkfsp.dgkilvtgseD..rtikvwdlstgkcv 87
           ++gh+++ ++ ++++p k+++atg  +rd++i +wd++t k ++ l+g h+ +v +++fs  dgk l++++ D  +ti +wd ++g+ +
   Q: 723  YMGHDDDILC-LAIHPLKDFVATGqvGRDSSIHIWDIETLKPMSVLKGfHQLGVCTLDFSAaDGKRLASVGLDenHTIVLWDWRKGEKL 810
           5778887777.************96669******************665**********962667********99************** PP
   S: 88   htlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           ++++g +d++  ++++p+  dkl++++ ++  + w+   g  +    + g++++ +c+v+  ++ +++sG+  + + +W  + ++l++t
   Q: 811  SAMRGSKDKIFVVKINPYLpDKLITAG-VKHMKFWHKAGGGLIGRkGNMGKTETMMCAVYGWSEEMVFSGTCSGDICIW--RDMFLMKT 896
           *****************9978888887.99*****8888887765799*******************************..88****** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            +  h+++v s+   +  k +v+g++dg v lwd + ++c++t+ 
   Q: 897  VKA-HDGPVFSVHALE--KGFVTGGKDGIVALWDDSFERCLKTYA 938
           *98.********9888..67**********************996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MADRTAPNCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYNAR EHKQKFYLGH 60
NDDIISLALH PERVLVATGQ VGKEPYICVW DSYTTQTVSI LKDVHTHGIA CLSFDLEGQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGACA GGACTGCTCC CAATTGCCAC CTAAGACTGG AGTGGGTTTA CGGATACCGG 60
GGACATCAGT GCCGCAACAA CCTGTACTAC ACGGCCGCCA AGGAAATAGT CTATTTCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	83.56	0.00e+00	3387.00
IUUC-Apl-003360	Anas platyrhynchos	85.94	0.00e+00	3371.00
IUUC-Ame-011681	Astyanax mexicanus	92.38	0.00e+00	3729.00
IUUC-Bta-012838	Bos taurus	82.61	0.00e+00	3396.00
IUUC-Cja-019068	Callithrix jacchus	83.10	0.00e+00	3404.00
IUUC-Cfa-020531	Canis familiaris	83.89	0.00e+00	3455.00
IUUC-Cpo-022304	Cavia porcellus	81.15	0.00e+00	3217.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	33.14	6.00e-99	357.00
IUUC-Csa-023621	Chlorocebus sabaeus	83.19	0.00e+00	3135.00
IUUC-Cho-024944	Choloepus hoffmanni	71.66	0.00e+00	1143.00
IUUC-Dre-028772	Danio rerio	91.62	0.00e+00	3690.00
IUUC-Dno-030063	Dasypus novemcinctus	82.58	0.00e+00	3382.00
IUUC-Dor-030980	Dipodomys ordii	76.34	0.00e+00	1445.00
IUUC-Ete-032554	Echinops telfairi	81.96	0.00e+00	948.00
IUUC-Eca-033909	Equus caballus	82.62	0.00e+00	3141.00
IUUC-Fal-037219	Ficedula albicollis	86.20	0.00e+00	3489.00
IUUC-Gmo-039146	Gadus morhua	89.68	0.00e+00	3608.00
IUUC-Gga-041095	Gallus gallus	86.15	0.00e+00	2548.00
IUUC-Gac-041341	Gasterosteus aculeatus	94.38	0.00e+00	3740.00
IUUC-Hsa-045997	Homo sapiens	83.00	0.00e+00	3404.00
IUUC-Lch-050306	Latimeria chalumnae	83.73	0.00e+00	3123.00
IUUC-Loc-052215	Lepisosteus oculatus	90.03	0.00e+00	3684.00
IUUC-Laf-054044	Loxodonta africana	82.01	0.00e+00	3376.00
IUUC-Mcc-054733	Macaca mulatta	82.89	0.00e+00	3398.00
IUUC-Meu-055977	Macropus eugenii	74.14	0.00e+00	1821.00
IUUC-Mga-059666	Meleagris gallopavo	84.09	0.00e+00	3304.00
IUUC-Mmr-060995	Microcebus murinus	83.08	0.00e+00	3400.00
IUUC-Mdo-062482	Monodelphis domestica	84.44	0.00e+00	3461.00
IUUC-Mmu-063533	Mus musculus	83.10	0.00e+00	3378.00
IUUC-Mpu-066704	Mustela putorius furo	83.50	0.00e+00	3429.00
IUUC-Mlu-067592	Myotis lucifugus	82.54	0.00e+00	3377.00
IUUC-Nle-069911	Nomascus leucogenys	83.23	0.00e+00	3405.00
IUUC-Ont-071966	Oreochromis niloticus	95.68	0.00e+00	3844.00
IUUC-Ola-086738	Oryzias latipes	94.18	0.00e+00	3796.00
IUUC-Olu-087860	Ostreococcus lucimarinus	36.38	2.00e-114	406.00
IUUC-Oga-088436	Otolemur garnettii	81.53	0.00e+00	3353.00
IUUC-Oar-090153	Ovis aries	83.13	0.00e+00	3293.00
IUUC-Ptr-091008	Pan troglodytes	82.04	0.00e+00	3379.00
IUUC-Pan-092404	Papio anubis	83.18	0.00e+00	3404.00
IUUC-Psi-093417	Pelodiscus sinensis	84.85	0.00e+00	3348.00
IUUC-Pfo-096073	Poecilia formosa	94.66	0.00e+00	3820.00
IUUC-Pab-097900	Pongo abelii	82.84	0.00e+00	3397.00
IUUC-Pca-100107	Procavia capensis	69.50	0.00e+00	2211.00
IUUC-Pva-102880	Pteropus vampyrus	80.25	0.00e+00	3143.00
IUUC-Rno-106084	Rattus norvegicus	83.05	0.00e+00	3423.00
IUUC-Sha-106974	Sarcophilus harrisii	84.38	0.00e+00	3449.00
IUUC-Sar-113401	Sorex araneus	74.95	0.00e+00	1634.00
IUUC-Ssc-116057	Sus scrofa	82.76	0.00e+00	3339.00
IUUC-Tsy-118941	Tarsius syrichta	73.04	0.00e+00	2501.00
IUUC-Tni-120683	Tetraodon nigroviridis	98.21	0.00e+00	3734.00
IUUC-Tbe-127467	Tupaia belangeri	76.84	0.00e+00	1621.00
IUUC-Ttr-129138	Tursiops truncatus	80.29	0.00e+00	3140.00
IUUC-Vpa-130083	Vicugna pacos	78.39	0.00e+00	3044.00
IUUC-Xtr-131835	Xenopus tropicalis	84.44	0.00e+00	3470.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence