iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037560

Ensembl Protein ID

ENSFALP00000005227.1

UniProt Accession

U3JR23; U3JR23_FICAL

Genbank Protein ID

ENSFALP00000005227

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01001444

Gene Name

TRAF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000005012.1	ENSFALT00000005252.1	ENSFALP00000005227.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	72.83	0.00e+00	738.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MAAANSSPPG SLDLNQPGFA KEILGTKLEV KYLCSDCKNI LRRPFQAQCG HRYCSYCLKK 60
IISAGPQKCA SCIQEGIYEE GISILETSSA FPDNAARREV ESLPAVCINS GCSWKGTIKE 120

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Nucleotide Sequence
(Fasta)

ATGCGGGCTG CGTCGCGCGC TTCGCCGGCA CGGCACTTTT CCTGCCATCG CCGTCCTGTG 60
GCCTCCGTCC TGCCGCCGCC CATCCTTCCC GACCGCTGGC CGCCCCCTGT CCCCCGAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	68.44	0.00e+00	731.00
IUUC-Apl-004202	Anas platyrhynchos	78.11	0.00e+00	830.00
IUUC-Aca-005029	Anolis carolinensis	55.50	2.00e-131	461.00
IUUC-Ame-011841	Astyanax mexicanus	51.65	2.00e-166	578.00
IUUC-Bta-013180	Bos taurus	70.18	0.00e+00	720.00
IUUC-Cja-019813	Callithrix jacchus	72.64	0.00e+00	756.00
IUUC-Cfa-021205	Canis familiaris	73.03	0.00e+00	740.00
IUUC-Cpo-021346	Cavia porcellus	72.83	0.00e+00	752.00
IUUC-Csa-023809	Chlorocebus sabaeus	72.99	0.00e+00	656.00
IUUC-Dre-027669	Danio rerio	54.76	3.00e-161	561.00
IUUC-Dno-029458	Dasypus novemcinctus	70.91	0.00e+00	733.00
IUUC-Dor-030338	Dipodomys ordii	68.91	0.00e+00	719.00
IUUC-Eca-034401	Equus caballus	72.83	0.00e+00	764.00
IUUC-Eeu-034668	Erinaceus europaeus	83.55	5.00e-77	281.00
IUUC-Fca-036057	Felis catus	70.34	0.00e+00	754.00
IUUC-Gmo-038964	Gadus morhua	58.71	1.00e-174	605.00
IUUC-Gga-040425	Gallus gallus	80.49	0.00e+00	846.00
IUUC-Gac-041908	Gasterosteus aculeatus	60.74	9.00e-180	622.00
IUUC-Ggo-044606	Gorilla gorilla	65.55	0.00e+00	665.00
IUUC-Hsa-046952	Homo sapiens	73.23	0.00e+00	759.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	63.62	6.00e-180	623.00
IUUC-Lch-049571	Latimeria chalumnae	57.31	0.00e+00	659.00
IUUC-Loc-051973	Lepisosteus oculatus	58.82	7.00e-173	600.00
IUUC-Laf-053815	Loxodonta africana	69.53	0.00e+00	705.00
IUUC-Mcc-054888	Macaca mulatta	73.23	0.00e+00	756.00
IUUC-Meu-056547	Macropus eugenii	82.44	3.00e-133	468.00
IUUC-Mga-059819	Meleagris gallopavo	79.76	0.00e+00	795.00
IUUC-Mdo-062570	Monodelphis domestica	75.93	0.00e+00	763.00
IUUC-Mmu-063133	Mus musculus	70.87	0.00e+00	712.00
IUUC-Mpu-065802	Mustela putorius furo	69.32	0.00e+00	734.00
IUUC-Nle-070155	Nomascus leucogenys	73.03	0.00e+00	762.00
IUUC-Opr-070856	Ochotona princeps	71.12	5.00e-96	344.00
IUUC-Ont-071930	Oreochromis niloticus	61.57	0.00e+00	652.00
IUUC-Ola-087397	Oryzias latipes	58.52	0.00e+00	632.00
IUUC-Oga-088109	Otolemur garnettii	73.03	0.00e+00	758.00
IUUC-Oar-090310	Ovis aries	86.81	3.00e-97	348.00
IUUC-Ptr-090643	Pan troglodytes	73.03	0.00e+00	761.00
IUUC-Pan-091933	Papio anubis	73.23	0.00e+00	755.00
IUUC-Psi-093681	Pelodiscus sinensis	74.22	0.00e+00	760.00
IUUC-Pfo-096148	Poecilia formosa	57.90	0.00e+00	637.00
IUUC-Pab-098631	Pongo abelii	73.03	0.00e+00	762.00
IUUC-Pca-100582	Procavia capensis	59.77	2.00e-78	286.00
IUUC-Pva-102396	Pteropus vampyrus	60.90	1.00e-172	599.00
IUUC-Rno-106120	Rattus norvegicus	70.61	0.00e+00	711.00
IUUC-Sha-106493	Sarcophilus harrisii	75.15	0.00e+00	772.00
IUUC-Sar-113570	Sorex araneus	86.74	4.00e-97	347.00
IUUC-Ssc-115843	Sus scrofa	69.22	0.00e+00	737.00
IUUC-Tgu-117144	Taeniopygia guttata	83.07	0.00e+00	822.00
IUUC-Tru-117853	Takifugu rubripes	58.94	0.00e+00	631.00
IUUC-Tni-120256	Tetraodon nigroviridis	62.01	0.00e+00	658.00
IUUC-Tbe-127943	Tupaia belangeri	59.47	4.00e-90	323.00
IUUC-Ttr-129246	Tursiops truncatus	71.51	0.00e+00	732.00
IUUC-Xtr-132279	Xenopus tropicalis	60.08	1.00e-170	592.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence