iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004506

Ensembl Protein ID

ENSACAP00000009849.3

UniProt Accession

G1KJM5; G1KJM5_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000009963.3	ENSACAT00000010051.3	ENSACAP00000009849.3
ENSACAG00000009963.3	ENSACAT00000030416.1	ENSACAP00000022996.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-30	103.6	1447	1481
UBD/Beta-Prp	1.80e-41	142.2	1314	1517

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g +kvW+++ ++
   Q: 1447 HKDWVCALAFvPSrPMLLSACRGGIVKVWNVDNFT 1481
           ***********888****************98765 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqclee... 131
            e +++++ ++p+g + + +++ + +++w+l+ ++++ +l+gh   v++l++++   + d +++Gs+d +++++++ +g   +    
   Q: 1314 GEHQINQIALNPTG-TTLYAASGNSVRIWELNRFQPIGKLSGHIGPVMCLTVNKtpsNHDLVITGSKDHYVKMFEIAEGVGGNFgpa 1399
           45679********9.8999999*******************************999777******************9988776888 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
             ++ +h + + c+++h+  ++l+sGs D+ ++ Wdl++++l+++   +h+d v  l+f ++++ l+s+ + g vk+w++ + + v 
   Q: 1400 hnFEPPHYDGIECLAIHG--DILFSGSRDNGIKKWDLEQQELIQQIPNAHKDWVCALAFVPSRPMLLSACRGGIVKVWNVDNFTPVG 1484
           889***************..**************************999************************************** PP
   S: 217  tlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
             +gh+++++ + +   ++++ ++ssD  +++W++
   Q: 1485 DIKGHDSPINAICTN--SKHIFTASSDCRVKLWNY 1517
           **********77777..****************96 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSISEEENGI IPRAITHLFN GIDERKRAAQ EQGVPAPEFK VSAQFLELYN EEILDLFDST 60
RDPDSRHRKS NIKIHEDANG GIYTTGVTSR LIGSQDELIQ CLKQGALSRT TASTQMNVQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGGAGCCC CTCCCCCTCT CCCTCCCCCG CCTCCTGCGC CCAGCAACGC GCAACTCGCG 60
GTGCCTCGAC AGTCCCGCTG GCGCTGCGGG GCGGGCAGGA TGGAGTGGGG TGCCGCGTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	80.65	0.00e+00	2251.00
IUUC-Ame-011515	Astyanax mexicanus	73.89	0.00e+00	1414.00
IUUC-Bta-013185	Bos taurus	65.74	0.00e+00	1727.00
IUUC-Cja-018844	Callithrix jacchus	79.15	0.00e+00	2241.00
IUUC-Cfa-021187	Canis familiaris	81.71	0.00e+00	2296.00
IUUC-Cpo-022444	Cavia porcellus	80.80	0.00e+00	2285.00
IUUC-Csa-023852	Chlorocebus sabaeus	81.72	0.00e+00	2313.00
IUUC-Dre-027839	Danio rerio	72.91	0.00e+00	1397.00
IUUC-Dno-030058	Dasypus novemcinctus	80.14	0.00e+00	2278.00
IUUC-Dor-030673	Dipodomys ordii	80.23	0.00e+00	2281.00
IUUC-Eca-033885	Equus caballus	80.25	0.00e+00	2250.00
IUUC-Eeu-035338	Erinaceus europaeus	67.66	0.00e+00	1723.00
IUUC-Fca-035388	Felis catus	81.84	0.00e+00	2317.00
IUUC-Fal-037044	Ficedula albicollis	81.66	0.00e+00	2409.00
IUUC-Gmo-039034	Gadus morhua	66.60	0.00e+00	1228.00
IUUC-Gac-041328	Gasterosteus aculeatus	70.01	0.00e+00	2053.00
IUUC-Ggo-045392	Gorilla gorilla	81.17	0.00e+00	2291.00
IUUC-Hsa-046713	Homo sapiens	81.72	0.00e+00	2310.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	81.83	0.00e+00	1446.00
IUUC-Lch-049786	Latimeria chalumnae	75.48	0.00e+00	2211.00
IUUC-Loc-052703	Lepisosteus oculatus	75.75	0.00e+00	2227.00
IUUC-Laf-054193	Loxodonta africana	72.75	0.00e+00	2010.00
IUUC-Mcc-055484	Macaca mulatta	80.50	0.00e+00	2300.00
IUUC-Meu-056278	Macropus eugenii	80.84	0.00e+00	1149.00
IUUC-Mga-059816	Meleagris gallopavo	81.24	0.00e+00	2297.00
IUUC-Mmr-061071	Microcebus murinus	78.85	0.00e+00	2260.00
IUUC-Mdo-062845	Monodelphis domestica	83.32	0.00e+00	1588.00
IUUC-Mmu-063967	Mus musculus	80.57	0.00e+00	2268.00
IUUC-Mpu-066448	Mustela putorius furo	80.58	0.00e+00	2294.00
IUUC-Nle-070037	Nomascus leucogenys	82.27	0.00e+00	1608.00
IUUC-Opr-070325	Ochotona princeps	77.52	0.00e+00	2135.00
IUUC-Ont-071851	Oreochromis niloticus	70.01	0.00e+00	2050.00
IUUC-Oan-073615	Ornithorhynchus anatinus	81.16	0.00e+00	2314.00
IUUC-Ocu-073855	Oryctolagus cuniculus	81.81	0.00e+00	2279.00
IUUC-Ola-086703	Oryzias latipes	69.57	0.00e+00	2034.00
IUUC-Oga-088171	Otolemur garnettii	79.86	0.00e+00	2249.00
IUUC-Oar-089693	Ovis aries	65.65	0.00e+00	1047.00
IUUC-Ptr-090535	Pan troglodytes	80.49	0.00e+00	1563.00
IUUC-Pan-091917	Papio anubis	80.86	0.00e+00	2093.00
IUUC-Psi-093752	Pelodiscus sinensis	75.50	0.00e+00	1341.00
IUUC-Pfo-096827	Poecilia formosa	68.00	0.00e+00	1308.00
IUUC-Pab-098441	Pongo abelii	80.95	0.00e+00	2316.00
IUUC-Pca-100781	Procavia capensis	88.56	0.00e+00	749.00
IUUC-Pva-103099	Pteropus vampyrus	77.67	0.00e+00	1164.00
IUUC-Rno-105872	Rattus norvegicus	82.15	0.00e+00	1573.00
IUUC-Sha-107097	Sarcophilus harrisii	80.68	0.00e+00	2249.00
IUUC-Ssc-115638	Sus scrofa	80.40	0.00e+00	1981.00
IUUC-Tgu-116504	Taeniopygia guttata	78.05	0.00e+00	1410.00
IUUC-Tru-118242	Takifugu rubripes	71.05	0.00e+00	2073.00
IUUC-Ttr-128824	Tursiops truncatus	76.86	0.00e+00	1950.00
IUUC-Xtr-131798	Xenopus tropicalis	60.93	0.00e+00	1652.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence