iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013185

Ensembl Protein ID

ENSBTAP00000054200.1

UniProt Accession

G3MXD5; G3MXD5_BOVIN

Genbank Protein ID

ENSBTAP00000054200

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02043983

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000047274.1	ENSBTAT00000063330.1	ENSBTAP00000054200.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-29	100.1	1503	1537
UBD/Beta-Prp	3.60e-42	144.7	1371	1573

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g++kvW+++ ++
   Q: 1503 HKDWVCALAFvPGrPMLLSACRAGVVKVWNVDNFT 1537
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 52   eaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqclee.... 131
           e +++++ +sp g  ++ +++ ++++vw+ls ++++ +l+gh   v++l+  +   ++d +v+Gs+d ++++++l +g         
   Q: 1371 EHQINQIALSPAG-SMLYAASGNAVRVWELSRFQPIAKLTGHIGPVMCLTAAQtagQRDLVVTGSKDHYVKMFELGEGVTGTIgpth 1456
           5679999*****9.78999999******************************998788******************99988778989 PP
   S: 132  .tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
            ++ +h + + c+++++  ++l+sGs D+ v+ Wdl+ ++l+++   +h+d v  l+f + ++ l+s+ + g vk+w++ + + + +
   Q: 1457 nFEPPHYDGIECLAIQG--DVLFSGSRDNGVKKWDLEHQELVQQIPTAHKDWVCALAFVPGRPMLLSACRAGVVKVWNVDNFTPIGE 1541
           9999***********99..9*************************888*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriWdl 251
            +gh+++++ + +   + ++ ++ssD  +++W++
   Q: 1542 IKGHDSPINAICTN--SRHIFTASSDCRVKLWNY 1573
           *********77777..****************96 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MAGQGDCCVK VAVRIRPQLS KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY DFVFDLDTWQ 60
EQIYSTCVSK LVEGCFEGYN ATVLAYGQTG AGKTYTMGTG FDVATAEEEQ GIIPRAIAHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGTCGCCCC GGGCATCGGC CCCCAGGCCC CCGCCCCTGA TCGACGCGGG CCCGGCACTG 60
CAGCGCCATG GCCGGTCAGG GGGACTGCTG CGTCAAGGTG GCCGTCAGGT AGGACGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	75.60	0.00e+00	2107.00
IUUC-Apl-003204	Anas platyrhynchos	63.71	0.00e+00	1170.00
IUUC-Aca-004506	Anolis carolinensis	65.80	0.00e+00	1779.00
IUUC-Ame-011515	Astyanax mexicanus	63.12	0.00e+00	1178.00
IUUC-Cja-018844	Callithrix jacchus	73.47	0.00e+00	2091.00
IUUC-Cfa-021187	Canis familiaris	75.38	0.00e+00	2173.00
IUUC-Cpo-022444	Cavia porcellus	74.21	0.00e+00	2135.00
IUUC-Csa-023852	Chlorocebus sabaeus	76.81	0.00e+00	2199.00
IUUC-Dno-030058	Dasypus novemcinctus	75.54	0.00e+00	2091.00
IUUC-Dor-030673	Dipodomys ordii	73.08	0.00e+00	1995.00
IUUC-Eca-033885	Equus caballus	75.23	0.00e+00	2089.00
IUUC-Eeu-035338	Erinaceus europaeus	70.95	0.00e+00	1140.00
IUUC-Fca-035388	Felis catus	75.44	0.00e+00	1984.00
IUUC-Fal-037044	Ficedula albicollis	71.31	0.00e+00	2031.00
IUUC-Gac-041328	Gasterosteus aculeatus	60.20	0.00e+00	1776.00
IUUC-Ggo-045392	Gorilla gorilla	76.56	0.00e+00	2191.00
IUUC-Hsa-046713	Homo sapiens	77.18	0.00e+00	2198.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	70.99	0.00e+00	1172.00
IUUC-Loc-052703	Lepisosteus oculatus	64.52	0.00e+00	1919.00
IUUC-Laf-054193	Loxodonta africana	67.81	0.00e+00	1803.00
IUUC-Mcc-055484	Macaca mulatta	75.12	0.00e+00	2154.00
IUUC-Meu-056278	Macropus eugenii	72.67	0.00e+00	996.00
IUUC-Mga-059816	Meleagris gallopavo	68.67	0.00e+00	1956.00
IUUC-Mmr-061071	Microcebus murinus	75.03	0.00e+00	2148.00
IUUC-Mdo-062845	Monodelphis domestica	72.59	0.00e+00	2093.00
IUUC-Mmu-063967	Mus musculus	75.99	0.00e+00	2141.00
IUUC-Mpu-066448	Mustela putorius furo	75.59	0.00e+00	2173.00
IUUC-Nle-070037	Nomascus leucogenys	72.75	0.00e+00	1543.00
IUUC-Opr-070325	Ochotona princeps	72.68	0.00e+00	1986.00
IUUC-Ont-071851	Oreochromis niloticus	62.07	0.00e+00	1139.00
IUUC-Oan-073615	Ornithorhynchus anatinus	70.17	0.00e+00	1856.00
IUUC-Ocu-073855	Oryctolagus cuniculus	76.64	0.00e+00	2150.00
IUUC-Ola-086703	Oryzias latipes	59.90	0.00e+00	1145.00
IUUC-Oga-088171	Otolemur garnettii	75.45	0.00e+00	2118.00
IUUC-Oar-089693	Ovis aries	59.39	0.00e+00	801.00
IUUC-Ptr-090535	Pan troglodytes	71.47	0.00e+00	1316.00
IUUC-Pan-091917	Papio anubis	74.81	0.00e+00	1975.00
IUUC-Psi-093752	Pelodiscus sinensis	58.89	0.00e+00	962.00
IUUC-Pfo-096827	Poecilia formosa	60.55	0.00e+00	1137.00
IUUC-Pab-098441	Pongo abelii	77.24	0.00e+00	2212.00
IUUC-Pca-100781	Procavia capensis	90.76	0.00e+00	735.00
IUUC-Pva-103099	Pteropus vampyrus	66.00	0.00e+00	890.00
IUUC-Rno-105872	Rattus norvegicus	74.95	0.00e+00	2175.00
IUUC-Sha-107097	Sarcophilus harrisii	71.11	0.00e+00	1990.00
IUUC-Ssc-115638	Sus scrofa	75.70	0.00e+00	1819.00
IUUC-Tgu-116504	Taeniopygia guttata	72.88	0.00e+00	1350.00
IUUC-Tru-118242	Takifugu rubripes	59.17	0.00e+00	1083.00
IUUC-Tsy-118951	Tarsius syrichta	79.49	0.00e+00	805.00
IUUC-Tni-119976	Tetraodon nigroviridis	80.28	0.00e+00	649.00
IUUC-Ttr-128824	Tursiops truncatus	70.21	0.00e+00	1970.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence