iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000002263.5	ENSGALT00000003547.4	ENSGALP00000003540.4
ENSGALG00000002263.5	ENSGALT00000003546.5	ENSGALP00000003539.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.40e-18	66.1	61	124
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.40e-10	40.3	160	191

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dvil+v+ +ef++h++vLaa+S +F+a+f ++l+e+  ++++ +k+v++e ++ ll++ Yt+k+
   Q: 61   TDVILCVDSREFSCHRVVLAAASNYFRAMFCNDLREKY-EEKIILKGVDAETMNILLDYTYTSKM 124
           7***********************************97.***********************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nc+gilr+Ad+++++ Lk++++++i+++F+
   Q: 160  PDNCVGILRLADAHSLHSLKQQVQNYIIQNFT 191
           89*****************************7 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MGDTLEKSCE DAEFSLDNEC STKMGELVEV SSGEKIKFDD TGLSLVLQNG LENLRLENSL 60
TDVILCVDSR EFSCHRVVLA AASNYFRAMF CNDLREKYEE KIILKGVDAE TMNILLDYTY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATCCGCC CAACTTCTGC AGTGTGACTC GTCTGAGGCT TAGGAACTCT CTTTTAGATC 60
GAGGCACCAA CAGAATGAGA CGGTGCTGGC CAGAACATGG GCGACACGCT GGAGAAGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011498--Kelch_2
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
PF07646--Kelch_2

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

gga:424762

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	84.26	0.00e+00	1098.00
IUUC-Apl-003490	Anas platyrhynchos	96.56	0.00e+00	1239.00
IUUC-Aca-005136	Anolis carolinensis	85.25	0.00e+00	1077.00
IUUC-Ame-010886	Astyanax mexicanus	68.94	0.00e+00	853.00
IUUC-Bta-013473	Bos taurus	83.28	0.00e+00	1060.00
IUUC-Cja-018888	Callithrix jacchus	83.44	0.00e+00	1091.00
IUUC-Cpo-021761	Cavia porcellus	75.99	0.00e+00	976.00
IUUC-Csa-023206	Chlorocebus sabaeus	84.26	0.00e+00	1097.00
IUUC-Cin-025367	Ciona intestinalis	40.43	2.00e-132	465.00
IUUC-Csv-026076	Ciona savignyi	42.04	8.00e-127	447.00
IUUC-Dre-027948	Danio rerio	73.91	0.00e+00	919.00
IUUC-Dno-030045	Dasypus novemcinctus	83.44	0.00e+00	1090.00
IUUC-Dor-030839	Dipodomys ordii	77.38	0.00e+00	981.00
IUUC-Eca-033608	Equus caballus	84.43	0.00e+00	1077.00
IUUC-Eeu-034640	Erinaceus europaeus	82.79	0.00e+00	1085.00
IUUC-Fca-036065	Felis catus	83.77	0.00e+00	1097.00
IUUC-Fal-036949	Ficedula albicollis	95.81	0.00e+00	1211.00
IUUC-Gmo-039661	Gadus morhua	62.24	3.00e-180	624.00
IUUC-Gac-042413	Gasterosteus aculeatus	61.18	0.00e+00	783.00
IUUC-Ggo-045167	Gorilla gorilla	84.26	0.00e+00	1097.00
IUUC-Hsa-046120	Homo sapiens	84.26	0.00e+00	1097.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	84.26	0.00e+00	1097.00
IUUC-Lch-049709	Latimeria chalumnae	81.92	0.00e+00	1084.00
IUUC-Loc-052239	Lepisosteus oculatus	83.12	0.00e+00	1003.00
IUUC-Laf-054511	Loxodonta africana	82.95	0.00e+00	1090.00
IUUC-Mcc-055109	Macaca mulatta	84.26	0.00e+00	1097.00
IUUC-Meu-056522	Macropus eugenii	71.43	1.00e-100	360.00
IUUC-Mga-060012	Meleagris gallopavo	97.71	0.00e+00	1237.00
IUUC-Mmr-061364	Microcebus murinus	83.44	0.00e+00	1089.00
IUUC-Mdo-063033	Monodelphis domestica	79.25	0.00e+00	975.00
IUUC-Mmu-063880	Mus musculus	82.30	0.00e+00	1049.00
IUUC-Mlu-068233	Myotis lucifugus	83.93	0.00e+00	1090.00
IUUC-Opr-070638	Ochotona princeps	82.92	0.00e+00	773.00
IUUC-Ont-071960	Oreochromis niloticus	61.58	0.00e+00	793.00
IUUC-Oan-073406	Ornithorhynchus anatinus	79.02	0.00e+00	1025.00
IUUC-Ocu-074612	Oryctolagus cuniculus	83.72	0.00e+00	1092.00
IUUC-Ola-087181	Oryzias latipes	59.64	0.00e+00	779.00
IUUC-Oga-088955	Otolemur garnettii	83.77	0.00e+00	1092.00
IUUC-Oar-089682	Ovis aries	83.28	0.00e+00	1060.00
IUUC-Ptr-090969	Pan troglodytes	84.26	0.00e+00	1097.00
IUUC-Pan-092289	Papio anubis	84.26	0.00e+00	1097.00
IUUC-Psi-093279	Pelodiscus sinensis	91.48	0.00e+00	1186.00
IUUC-Pab-097957	Pongo abelii	86.18	0.00e+00	840.00
IUUC-Pca-100619	Procavia capensis	80.98	0.00e+00	1077.00
IUUC-Pva-102533	Pteropus vampyrus	81.94	4.00e-179	621.00
IUUC-Rno-106111	Rattus norvegicus	82.13	0.00e+00	1076.00
IUUC-Sha-106716	Sarcophilus harrisii	79.34	0.00e+00	1018.00
IUUC-Tgu-116839	Taeniopygia guttata	96.07	0.00e+00	1229.00
IUUC-Tru-117792	Takifugu rubripes	62.83	0.00e+00	768.00
IUUC-Tsy-119609	Tarsius syrichta	75.34	5.00e-129	454.00
IUUC-Tni-119682	Tetraodon nigroviridis	60.13	0.00e+00	768.00
IUUC-Tme-127039	Tuber melanosporum	30.46	2.00e-12	68.60
IUUC-Tbe-127961	Tupaia belangeri	79.51	0.00e+00	996.00
IUUC-Ttr-128917	Tursiops truncatus	82.35	0.00e+00	890.00
IUUC-Vpa-130721	Vicugna pacos	85.11	0.00e+00	769.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence