iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-101261

Ensembl Protein ID

EMJ00903

UniProt Accession

M5VVF7; M5VVF7_PRUPE

Genbank Protein ID

EMJ00903.1

Protein Name

Protein HIRA

Genbank Nucleotide ID

KB639104

Gene Name

HIRA; PRUPE_ppa000833mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa000833mg	EMJ00903	EMJ00903

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-22	78.8	123	160
UBD/Beta-Prp	7.50e-42	144.0	13	207

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt++v +l++ +d  +l+sGs D+ti++W+++ g ++
   Q: 123  GHTADVVDLNWsPDdSMLASGSLDNTIHIWNMSNGICT 160
           8***********777****************9998886 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw.................dls 82
             +i ++++ p++  latg+ d++++vw++++              l++l +h + v++v++ ++g + ++gs+D++i +                  d++
   Q: 13   GMQIFSIDVQPGGLRLATGGGDHKVRVWNMKSLGRdleneessqrlLATLRDHFGSVNCVRWAKHGRYVASGSDDQVILIHerkpgsgttefgsgeppDVE 113
           556778999*********************9955599********************************************88888888888888888888 PP
   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           + k  +tl+gh+++v++l++sp+++ l+sGs d+ti++w++++g c   +l+gh+++v +v+++p g+ ++s s+D+tv +W+ +  +l ++  g
   Q: 114  NWKVAMTLRGHTADVVDLNWSPDDSMLASGSLDNTIHIWNMSNGICTA-VLRGHSSLVKGVTWDPIGSFIASQSDDKTVIIWRTSDWSLAHRTDG 207
           ************************************************.*********************************9977777777665 PP

Organism

Prunus persica

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MIAEKPSWIR HEGMQIFSID VQPGGLRLAT GGGDHKVRVW NMKSLGRDLE NEESSQRLLA 60
TLRDHFGSVN CVRWAKHGRY VASGSDDQVI LIHERKPGSG TTEFGSGEPP DVENWKVAMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGACGGAAAG GGAGGGCTTT CACCTCGCAA GTTAACTGCT TTCTCACTCT CACTCTCACA 60
AGCTCGCAAG CTTCATTCTC TCTCAACTCT GGCTTCTTCA TTCACGTAAA GGTAAATAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

pper:PRUPE_ppa000833mg

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	68.49	0.00e+00	1400.00
IUUC-Aml-001723	Ailuropoda melanoleuca	37.16	5.00e-81	295.00
IUUC-Atr-003132	Amborella trichopoda	69.89	0.00e+00	1395.00
IUUC-Apl-003197	Anas platyrhynchos	36.73	6.00e-82	298.00
IUUC-Aca-004733	Anolis carolinensis	37.17	5.00e-85	308.00
IUUC-Aly-005446	Arabidopsis lyrata	70.60	0.00e+00	1347.00
IUUC-Ath-007627	Arabidopsis thaliana	67.94	0.00e+00	1346.00
IUUC-Ago-007766	Ashbya gossypii	31.35	1.00e-62	234.00
IUUC-Acl-008104	Aspergillus clavatus	31.91	5.00e-68	252.00
IUUC-Afl-008591	Aspergillus flavus	33.41	8.00e-68	251.00
IUUC-Afu-008781	Aspergillus fumigatus	31.60	6.00e-62	231.00
IUUC-Ani-009272	Aspergillus nidulans	29.45	1.00e-52	201.00
IUUC-Ang-009655	Aspergillus niger	33.72	4.00e-67	249.00
IUUC-Aor-010119	Aspergillus oryzae	33.41	9.00e-68	251.00
IUUC-Ate-010530	Aspergillus terreus	29.37	1.00e-53	204.00
IUUC-Bgr-012237	Blumeria graminis	34.36	1.00e-64	241.00
IUUC-Bta-013320	Bos taurus	38.20	9.00e-81	294.00
IUUC-Bci-013795	Botrytis cinerea	34.58	3.00e-71	263.00
IUUC-Bdi-014075	Brachypodium distachyon	71.07	0.00e+00	1432.00
IUUC-Bol-016440	Brassica oleracea	69.64	0.00e+00	1348.00
IUUC-Bra-016651	Brassica rapa	69.95	0.00e+00	1317.00
IUUC-Cel-018692	Caenorhabditis elegans	27.92	2.00e-42	167.00
IUUC-Cja-018987	Callithrix jacchus	37.92	2.00e-74	273.00
IUUC-Cfa-020132	Canis familiaris	36.85	4.00e-81	295.00
IUUC-Cpo-021484	Cavia porcellus	37.17	3.00e-85	309.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	35.71	5.00e-71	261.00
IUUC-Csa-023081	Chlorocebus sabaeus	38.07	1.00e-86	314.00
IUUC-Cin-025182	Ciona intestinalis	37.10	1.00e-83	304.00
IUUC-Csv-026154	Ciona savignyi	36.07	3.00e-82	299.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	35.13	9.00e-66	244.00
IUUC-Cne-026891	Cryptococcus neoformans	41.91	7.00e-81	294.00
IUUC-Cme-027349	Cyanidioschyzon merolae	29.14	6.00e-52	198.00
IUUC-Dre-027655	Danio rerio	36.46	2.00e-82	300.00
IUUC-Dno-029557	Dasypus novemcinctus	37.47	5.00e-70	258.00
IUUC-Dor-030687	Dipodomys ordii	33.55	5.00e-65	241.00
IUUC-Dse-031334	Dothistroma septosporum	26.45	4.00e-90	325.00
IUUC-Dme-031746	Drosophila melanogaster	34.85	1.00e-84	306.00
IUUC-Ete-032384	Echinops telfairi	33.76	5.00e-62	232.00
IUUC-Eca-033430	Equus caballus	37.18	1.00e-82	300.00
IUUC-Fca-036121	Felis catus	36.91	6.00e-82	298.00
IUUC-Fal-036817	Ficedula albicollis	36.51	1.00e-81	297.00
IUUC-Fox-037906	Fusarium oxysporum	34.79	3.00e-69	255.00
IUUC-Fso-038409	Fusarium solani	34.12	3.00e-66	246.00
IUUC-Gmo-039151	Gadus morhua	39.43	5.00e-81	295.00
IUUC-Ggr-040016	Gaeumannomyces graminis	34.95	1.00e-67	250.00
IUUC-Gga-040936	Gallus gallus	37.27	1.00e-84	307.00
IUUC-Gac-041405	Gasterosteus aculeatus	35.54	3.00e-81	295.00
IUUC-Gma-044252	Glycine max	80.59	0.00e+00	1604.00
IUUC-Ggo-045430	Gorilla gorilla	38.07	9.00e-87	314.00
IUUC-Hsa-046442	Homo sapiens	38.07	7.00e-87	314.00
IUUC-Hvu-047587	Hordeum vulgare	70.78	0.00e+00	1345.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	41.01	2.00e-61	228.00
IUUC-Kpa-049145	Komagataella pastoris	29.09	9.00e-58	218.00
IUUC-Lch-050474	Latimeria chalumnae	36.25	2.00e-82	300.00
IUUC-Lpe-051209	Leersia perrieri	69.86	0.00e+00	1376.00
IUUC-Loc-052119	Lepisosteus oculatus	36.25	2.00e-80	293.00
IUUC-Lma-053237	Leptosphaeria maculans	32.93	4.00e-65	242.00
IUUC-Laf-053718	Loxodonta africana	37.19	1.00e-86	313.00
IUUC-Mcc-055621	Macaca mulatta	37.50	7.00e-75	275.00
IUUC-Meu-055914	Macropus eugenii	39.18	1.00e-53	204.00
IUUC-Mor-057090	Magnaporthe oryzae	35.28	2.00e-68	253.00
IUUC-Mpo-057364	Magnaporthe poae	34.95	3.00e-68	252.00
IUUC-Mtr-057744	Medicago truncatula	78.36	0.00e+00	1575.00
IUUC-Mla-058914	Melampsora laricipopulina	26.63	4.00e-78	285.00
IUUC-Mga-060181	Meleagris gallopavo	37.29	2.00e-80	293.00
IUUC-Mvi-060432	Microbotryum violaceum	32.66	1.00e-56	214.00
IUUC-Mmr-060871	Microcebus murinus	37.60	5.00e-87	315.00
IUUC-Mdo-062301	Monodelphis domestica	36.57	5.00e-86	311.00
IUUC-Mmu-063888	Mus musculus	38.27	2.00e-87	316.00
IUUC-Mac-065137	Musa acuminata	72.25	0.00e+00	1355.00
IUUC-Mpu-066732	Mustela putorius furo	37.16	4.00e-81	295.00
IUUC-Mlu-067542	Myotis lucifugus	37.53	6.00e-83	301.00
IUUC-Nfi-068396	Neosartorya fischeri	31.60	8.00e-62	231.00
IUUC-Ncr-068842	Neurospora crassa	36.05	9.00e-72	264.00
IUUC-Nle-070156	Nomascus leucogenys	37.40	3.00e-86	312.00
IUUC-Opr-070808	Ochotona princeps	35.77	3.00e-53	202.00
IUUC-Ont-072105	Oreochromis niloticus	36.27	2.00e-80	293.00
IUUC-Ocu-074962	Oryctolagus cuniculus	37.39	1.00e-82	300.00
IUUC-Oba-075178	Oryza barthii	70.14	0.00e+00	1378.00
IUUC-Obr-076399	Oryza brachyantha	71.49	0.00e+00	1392.00
IUUC-Ogu-078797	Oryza glumaepatula	70.14	0.00e+00	1378.00
IUUC-Oin-080085	Oryza indica	69.69	0.00e+00	1301.00
IUUC-Olo-081048	Oryza longistaminata	69.95	7.00e-172	597.00
IUUC-Ome-081324	Oryza meridionalis	70.14	0.00e+00	1377.00
IUUC-Oni-082548	Oryza nivara	70.04	0.00e+00	1377.00
IUUC-Opu-084008	Oryza punctata	76.36	0.00e+00	763.00
IUUC-Oru-084339	Oryza rufipogon	70.04	0.00e+00	1375.00
IUUC-Osa-085782	Oryza sativa	70.04	0.00e+00	1375.00
IUUC-Ola-087302	Oryzias latipes	34.83	3.00e-77	282.00
IUUC-Olu-087611	Ostreococcus lucimarinus	42.65	1.00e-116	413.00
IUUC-Oga-087935	Otolemur garnettii	37.76	2.00e-83	303.00
IUUC-Oar-089229	Ovis aries	32.73	5.00e-65	242.00
IUUC-Ptr-090715	Pan troglodytes	38.07	9.00e-87	314.00
IUUC-Pan-092318	Papio anubis	37.63	1.00e-82	300.00
IUUC-Psi-094053	Pelodiscus sinensis	36.18	8.00e-81	294.00
IUUC-Pno-094985	Phaeosphaeria nodorum	31.16	1.00e-58	221.00
IUUC-Ppa-095499	Physcomitrella patens	50.98	0.00e+00	937.00
IUUC-Pfo-096857	Poecilia formosa	35.79	2.00e-78	286.00
IUUC-Pab-098047	Pongo abelii	38.07	9.00e-87	314.00
IUUC-Pop-099587	Populus trichocarpa	79.76	0.00e+00	1550.00
IUUC-Pca-100558	Procavia capensis	47.67	2.00e-47	183.00
IUUC-Pva-102683	Pteropus vampyrus	37.40	5.00e-84	305.00
IUUC-Pgr-103660	Puccinia graminis	36.39	3.00e-62	232.00
IUUC-Ptt-103900	Puccinia triticina	36.93	9.00e-63	234.00
IUUC-Pte-104209	Pyrenophora teres	33.80	4.00e-69	255.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	33.80	3.00e-68	252.00
IUUC-Rno-105566	Rattus norvegicus	38.27	2.00e-87	316.00
IUUC-Sce-106291	Saccharomyces cerevisiae	32.49	5.00e-66	245.00
IUUC-Sha-107514	Sarcophilus harrisii	33.81	3.00e-70	259.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	27.52	5.00e-87	315.00
IUUC-Spo-108162	Schizosaccharomyces pombe	37.03	1.00e-72	267.00
IUUC-Smo-109186	Selaginella moellendorffii	51.38	0.00e+00	923.00
IUUC-Sit-110730	Setaria italica	71.99	0.00e+00	1402.00
IUUC-Sly-111547	Solanum lycopersicum	75.77	0.00e+00	1444.00
IUUC-Stu-112705	Solanum tuberosum	75.13	0.00e+00	1446.00
IUUC-Sar-113222	Sorex araneus	36.34	7.00e-76	278.00
IUUC-Sbi-114272	Sorghum bicolor	70.67	0.00e+00	1380.00
IUUC-Sre-115061	Sporisorium reilianum	34.02	8.00e-71	261.00
IUUC-Ssc-116364	Sus scrofa	36.97	2.00e-82	300.00
IUUC-Tgu-116645	Taeniopygia guttata	36.51	6.00e-82	298.00
IUUC-Tru-117590	Takifugu rubripes	36.51	1.00e-84	306.00
IUUC-Tsy-119212	Tarsius syrichta	34.74	2.00e-68	253.00
IUUC-Tni-119915	Tetraodon nigroviridis	36.42	3.00e-84	305.00
IUUC-Tca-121765	Theobroma cacao	81.22	0.00e+00	1603.00
IUUC-Tre-121887	Trichoderma reesei	33.41	1.00e-59	224.00
IUUC-Tvi-122262	Trichoderma virens	33.18	2.00e-59	223.00
IUUC-Tae-123009	Triticum aestivum	54.90	0.00e+00	876.00
IUUC-Tur-126483	Triticum urartu	70.94	0.00e+00	1421.00
IUUC-Tme-127202	Tuber melanosporum	30.35	1.00e-47	184.00
IUUC-Tbe-127350	Tupaia belangeri	33.51	9.00e-48	184.00
IUUC-Ttr-129077	Tursiops truncatus	34.95	6.00e-72	265.00
IUUC-Uma-129465	Ustilago maydis	33.40	1.00e-73	270.00
IUUC-Vda-129844	Verticillium dahliae	32.13	3.00e-66	246.00
IUUC-Vvi-131397	Vitis vinifera	81.21	0.00e+00	1623.00
IUUC-Xtr-132057	Xenopus tropicalis	36.33	2.00e-85	309.00
IUUC-Xma-134139	Xiphophorus maculatus	34.62	5.00e-68	251.00
IUUC-Yli-134424	Yarrowia lipolytica	35.45	2.00e-64	240.00
IUUC-Zma-135839	Zea mays	70.66	0.00e+00	1389.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence