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Tag Content
UUCD2 ID IUUC-Bta-012738
UUCD1 version UUC-BoT-01113
Ensembl Protein ID ENSBTAP00000011598.4
UniProt Accession F1N0I6; F1N0I6_BOVIN
Genbank Protein ID ENSBTAP00000011598
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID DAAA02028746
Gene Name USP3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000008805.4 ENSBTAT00000011598.4 ENSBTAP00000011598.4
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.10e-100 336.4 160 511
UBD/ZnF/ZnF_UBP 3.90e-27 94.4 27 105
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ e++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 160  TGLRNLGNTCFMNAILQSLSNIEQFCCYFKElpavelrngktAGRRTYHTRSQGENNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVW 248
           7******************************888888777775555555555688889******************************* PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           k+ ++f+gy+qqDa+Ef+++lld+l+ el+   n    ++  +++s+l + +++   +  +++++ +F+g l++++ cl c+++s +++
   Q: 249  KIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGISRSSILQENSTL-SASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFD 336
           *****************************7744444444433333333.345688899999**************************** PP
   S: 168  pfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
           pfldlsl++p++  +k +         sl+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++   + r+
   Q: 337  PFLDLSLDIPSQFRNKRSknqengptcSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTA--YLRN 423
           **********66655444667899999****************************************************7755..799* PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           k++++vefpl+ Ld++ ++ +pe++  e++ Y+L avvvH+G +++sGHY+ay+ + +g+W++f+Ds+Vt ++e++vl+   ++aY+lf
   Q: 424  KVDTYVEFPLRgLDMKCYLLEPENSGPENCLYDLAAVVVHHGsGVGSGHYTAYATH-EGRWFHFNDSTVTLTDEDTVLK---AKAYILF 508
           ********************************************************.9*********************...******* PP
   S: 335  Ykr 337
           Y +
   Q: 509  YVE 511
           *76 PP
   

   UBD/ZnF/ZnF_UBP
   S: 1    kkcsv.cdktenlWlcLtcgsvgCGRyvegHalkHyeetqhpl................vlslstlsvycYacddyvhr 62
           ++cs  c++++++W+cLtc+sv+CGRyv+gHa+kHye++q pl                ++++s++s+ycY+cdd+v++
   Q: 27   WCCSAvCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLtnhkksekqekaqhtvCMDCSSYSTYCYRCDDFVVN 105
           899877***********************************************************************85 PP
   
Organism Bos taurus
Protein Sequence
(Fasta)
MECPHLSSSV CIAPDSAKFP NGSPSSWCCS AVCRSNKSPW VCLTCSSVHC GRYVNGHAKK 60
HYEDAQIPLT NHKKSEKQEK AQHTVCMDCS SYSTYCYRCD DFVVNDTKLG LVQKVREHLQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-012738|DUB,USP;UBD,ZnF_UBP|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGACGCAGC CGCCGTCGGC CGAGCGTCGG GCGAGGAGCG ACCCCAGACG GAGTCGTCGG 60
AGTTCCTCCG CCCCCGCCTC GCCGGGTCCC GGAGCCTCAG TCCTCGCAGC TCTTCTGGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-012738|DUB,USP;UBD,ZnF_UBP|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0070938--C:contractile ring
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0000278--P:mitotic cell cycle
GO:0031647--P:regulation of protein stability
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001537 Ailuropoda melanoleuca 97.31 0.00e+00 951.00
IUUC-Apl-003358 Anas platyrhynchos 95.52 0.00e+00 899.00
IUUC-Aca-004454 Anolis carolinensis 92.01 0.00e+00 825.00
IUUC-Ame-011544 Astyanax mexicanus 76.83 0.00e+00 737.00
IUUC-Cel-018186 Caenorhabditis elegans 37.08 3.00e-55 209.00
IUUC-Cja-018893 Callithrix jacchus 96.93 0.00e+00 943.00
IUUC-Cfa-020607 Canis familiaris 97.89 0.00e+00 937.00
IUUC-Cpo-021828 Cavia porcellus 95.20 0.00e+00 911.00
IUUC-Csa-023884 Chlorocebus sabaeus 97.88 0.00e+00 775.00
IUUC-Cho-024863 Choloepus hoffmanni 87.72 0.00e+00 811.00
IUUC-Dre-028452 Danio rerio 74.10 0.00e+00 746.00
IUUC-Dno-029531 Dasypus novemcinctus 96.73 0.00e+00 869.00
IUUC-Dor-030913 Dipodomys ordii 88.92 8.00e-177 613.00
IUUC-Ete-032611 Echinops telfairi 90.98 0.00e+00 874.00
IUUC-Eca-033622 Equus caballus 98.37 0.00e+00 879.00
IUUC-Eeu-035268 Erinaceus europaeus 92.64 0.00e+00 802.00
IUUC-Fca-035801 Felis catus 97.14 0.00e+00 905.00
IUUC-Fal-036749 Ficedula albicollis 94.70 0.00e+00 852.00
IUUC-Gmo-039598 Gadus morhua 76.76 0.00e+00 766.00
IUUC-Gga-040883 Gallus gallus 95.72 0.00e+00 865.00
IUUC-Gac-042235 Gasterosteus aculeatus 76.82 0.00e+00 744.00
IUUC-Ggo-044767 Gorilla gorilla 91.65 0.00e+00 835.00
IUUC-Hsa-046581 Homo sapiens 97.12 0.00e+00 966.00
IUUC-Itr-047898 Ictidomys tridecemlineatus 97.89 0.00e+00 937.00
IUUC-Lch-049732 Latimeria chalumnae 90.60 0.00e+00 911.00
IUUC-Loc-052371 Lepisosteus oculatus 88.87 0.00e+00 898.00
IUUC-Laf-054565 Loxodonta africana 97.70 0.00e+00 935.00
IUUC-Mcc-055522 Macaca mulatta 97.50 0.00e+00 971.00
IUUC-Meu-056754 Macropus eugenii 86.34 6.00e-176 610.00
IUUC-Mga-060095 Meleagris gallopavo 94.96 0.00e+00 639.00
IUUC-Mmr-060839 Microcebus murinus 97.70 0.00e+00 934.00
IUUC-Mdo-062339 Monodelphis domestica 97.01 0.00e+00 756.00
IUUC-Mmu-063638 Mus musculus 96.16 0.00e+00 902.00
IUUC-Mpu-066647 Mustela putorius furo 98.16 0.00e+00 763.00
IUUC-Mlu-067921 Myotis lucifugus 96.73 0.00e+00 893.00
IUUC-Nle-069752 Nomascus leucogenys 97.89 0.00e+00 972.00
IUUC-Opr-070636 Ochotona princeps 82.73 0.00e+00 726.00
IUUC-Ont-071638 Oreochromis niloticus 77.05 0.00e+00 702.00
IUUC-Oan-073417 Ornithorhynchus anatinus 90.21 0.00e+00 886.00
IUUC-Ocu-074620 Oryctolagus cuniculus 95.97 0.00e+00 920.00
IUUC-Ola-087281 Oryzias latipes 79.03 0.00e+00 630.00
IUUC-Olu-087697 Ostreococcus lucimarinus 40.00 6.00e-49 187.00
IUUC-Oga-088448 Otolemur garnettii 96.74 0.00e+00 959.00
IUUC-Oar-090132 Ovis aries 98.66 0.00e+00 943.00
IUUC-Ptr-090696 Pan troglodytes 97.56 0.00e+00 910.00
IUUC-Pan-092124 Papio anubis 97.12 0.00e+00 966.00
IUUC-Psi-093801 Pelodiscus sinensis 96.09 0.00e+00 748.00
IUUC-Pma-094472 Petromyzon marinus 72.81 1.00e-94 338.00
IUUC-Pfo-096330 Poecilia formosa 78.35 0.00e+00 776.00
IUUC-Pab-098191 Pongo abelii 97.70 0.00e+00 971.00
IUUC-Pca-100341 Procavia capensis 95.61 0.00e+00 719.00
IUUC-Pva-103177 Pteropus vampyrus 97.31 0.00e+00 922.00
IUUC-Rno-105048 Rattus norvegicus 94.84 0.00e+00 885.00
IUUC-Sha-107429 Sarcophilus harrisii 95.78 0.00e+00 869.00
IUUC-Sar-113024 Sorex araneus 96.16 0.00e+00 819.00
IUUC-Ssc-115749 Sus scrofa 97.15 6.00e-152 529.00
IUUC-Tgu-117277 Taeniopygia guttata 94.69 0.00e+00 885.00
IUUC-Tru-117844 Takifugu rubripes 78.54 0.00e+00 775.00
IUUC-Tsy-119456 Tarsius syrichta 94.89 0.00e+00 865.00
IUUC-Tni-120251 Tetraodon nigroviridis 74.95 0.00e+00 791.00
IUUC-Tbe-127423 Tupaia belangeri 91.36 0.00e+00 849.00
IUUC-Ttr-128401 Tursiops truncatus 92.23 0.00e+00 800.00
IUUC-Vpa-130549 Vicugna pacos 88.02 1.00e-163 568.00
IUUC-Xtr-131892 Xenopus tropicalis 82.83 0.00e+00 794.00
Created Date 25-Jun-2017

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