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Tag Content
UUCD2 ID IUUC-Cpo-021828
UUCD1 version UUC-CaP-01065
Ensembl Protein ID ENSCPOP00000005316.2
UniProt Accession H0V6J6; H0V6J6_CAVPO
Genbank Protein ID ENSCPOP00000005316
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AAKN02009840
Gene Name USP3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000005893.3 ENSCPOT00000005956.2 ENSCPOP00000005316.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.90e-99 331.7 159 510
UBD/ZnF/ZnF_UBP 1.40e-27 95.7 27 104
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ +++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 159  TGLRNLGNTCFMNAILQSLSNIEQFCCYFKElpavelrngktAGRRTYHTRSQGDSSVSLVEEFRKTLCALWQGSQTAFSPESLFYVVW 247
           7******************************888888777775555555556688999******************************* PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           k+ ++f+gy+qqDa+Ef+++lld+l+ el+   n    ++  +++s+l   +++   +  +++++ +F+g l++++ cl c+++s +++
   Q: 248  KIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSGTAILQENSSL-AASNKCCINGASTVVTAVFGGVLQNEVNCLICGTESRKFD 335
           *****************************6644433333333333333.335678899999**************************** PP
   S: 168  pfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
           pfldlsl++p++  +k +         sl+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++   + r+
   Q: 336  PFLDLSLDIPSQFRSKRSknqengpvcSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTA--YLRN 422
           **********77655555678899999****************************************************7755..799* PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           k++++vefpl+ Ld++ ++ +pe++  e++ Y+L avvvH+G +++sGHY+ay+ + +g+W++f+Ds+Vt ++e++v +   ++aY+lf
   Q: 423  KVDTYVEFPLRgLDMKCYLLEPENSGPESCLYDLAAVVVHHGsGVGSGHYTAYAVH-EGRWFHFNDSTVTLTDEDTVGK---AKAYILF 507
           ********************************************************.9*********************...******* PP
   S: 335  Ykr 337
           Y +
   Q: 508  YVE 510
           *76 PP
   

   UBD/ZnF/ZnF_UBP
   S: 1    kkcsvcdktenlWlcLtcgsvgCGRyvegHalkHyeetqhpl................vlslstlsvycYacddyvhr 62
           ++csvc++++++W+cLtc+sv+CGRyv+gHa+kHye++q pl                ++++s++s+ycY+cdd+v++
   Q: 27   WCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLtnfkksekqdkpqhtvCMDCSSYSTYCYRCDDFVVN 104
           9***************************************************************************85 PP
   
Organism Cavia porcellus
Protein Sequence
(Fasta)
MECPHLSASV CIAPDSAKFP HGSPSSWCCS VCRSNKSPWV CLTCSSVHCG RYVNGHAKKH 60
YEDAQIPLTN FKKSEKQDKP QHTVCMDCSS YSTYCYRCDD FVVNDTKLGL VQKVREHLQN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-021828|DUB,USP;UBD,ZnF_UBP|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGAATGTC CGCACCTCAG CGCTAGCGTC TGCATCGCCC CGGACTCCGC CAAGTTCCCC 60
CACGGCTCCC CGTCGTCCTG GTGCTGCAGC GGTGAGTGCG GTCCTGGCCG TCACCCGAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-021828|DUB,USP;UBD,ZnF_UBP|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0070938--C:contractile ring
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0000278--P:mitotic cell cycle
GO:0031647--P:regulation of protein stability
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001537 Ailuropoda melanoleuca 95.77 0.00e+00 940.00
IUUC-Apl-003358 Anas platyrhynchos 94.08 0.00e+00 881.00
IUUC-Aca-004454 Anolis carolinensis 89.84 0.00e+00 809.00
IUUC-Ame-011544 Astyanax mexicanus 77.56 0.00e+00 744.00
IUUC-Bta-012738 Bos taurus 95.20 0.00e+00 915.00
IUUC-Cel-018186 Caenorhabditis elegans 36.97 4.00e-55 209.00
IUUC-Cja-018893 Callithrix jacchus 96.15 0.00e+00 936.00
IUUC-Cfa-020607 Canis familiaris 96.15 0.00e+00 926.00
IUUC-Csa-023884 Chlorocebus sabaeus 96.47 0.00e+00 763.00
IUUC-Cho-024863 Choloepus hoffmanni 85.96 0.00e+00 798.00
IUUC-Dre-028452 Danio rerio 74.43 0.00e+00 749.00
IUUC-Dno-029531 Dasypus novemcinctus 94.90 0.00e+00 853.00
IUUC-Dor-030913 Dipodomys ordii 87.43 1.00e-174 605.00
IUUC-Ete-032611 Echinops telfairi 90.00 0.00e+00 863.00
IUUC-Eca-033622 Equus caballus 96.12 0.00e+00 860.00
IUUC-Eeu-035268 Erinaceus europaeus 91.00 0.00e+00 786.00
IUUC-Fca-035801 Felis catus 95.92 0.00e+00 892.00
IUUC-Fal-036749 Ficedula albicollis 93.28 0.00e+00 842.00
IUUC-Gmo-039598 Gadus morhua 75.93 0.00e+00 763.00
IUUC-Gga-040883 Gallus gallus 94.29 0.00e+00 850.00
IUUC-Gac-042235 Gasterosteus aculeatus 75.24 0.00e+00 737.00
IUUC-Ggo-044767 Gorilla gorilla 90.63 0.00e+00 823.00
IUUC-Hsa-046581 Homo sapiens 95.77 0.00e+00 951.00
IUUC-Itr-047898 Ictidomys tridecemlineatus 96.15 0.00e+00 923.00
IUUC-Lch-049732 Latimeria chalumnae 89.23 0.00e+00 900.00
IUUC-Loc-052371 Lepisosteus oculatus 88.08 0.00e+00 891.00
IUUC-Laf-054565 Loxodonta africana 95.58 0.00e+00 917.00
IUUC-Mcc-055522 Macaca mulatta 95.96 0.00e+00 956.00
IUUC-Meu-056754 Macropus eugenii 83.84 1.00e-172 599.00
IUUC-Mga-060095 Meleagris gallopavo 92.58 0.00e+00 627.00
IUUC-Mmr-060839 Microcebus murinus 96.15 0.00e+00 922.00
IUUC-Mdo-062339 Monodelphis domestica 95.40 0.00e+00 745.00
IUUC-Mmu-063638 Mus musculus 95.38 0.00e+00 901.00
IUUC-Mpu-066647 Mustela putorius furo 96.32 0.00e+00 750.00
IUUC-Mlu-067921 Myotis lucifugus 94.49 0.00e+00 876.00
IUUC-Nle-069752 Nomascus leucogenys 95.96 0.00e+00 955.00
IUUC-Opr-070636 Ochotona princeps 81.73 0.00e+00 724.00
IUUC-Ont-071638 Oreochromis niloticus 76.00 0.00e+00 694.00
IUUC-Oan-073417 Ornithorhynchus anatinus 88.46 0.00e+00 873.00
IUUC-Ocu-074620 Oryctolagus cuniculus 94.81 0.00e+00 915.00
IUUC-Ola-087281 Oryzias latipes 78.80 0.00e+00 629.00
IUUC-Olu-087697 Ostreococcus lucimarinus 39.30 7.00e-48 184.00
IUUC-Oga-088448 Otolemur garnettii 95.38 0.00e+00 947.00
IUUC-Oar-090132 Ovis aries 95.19 0.00e+00 919.00
IUUC-Ptr-090696 Pan troglodytes 95.93 0.00e+00 893.00
IUUC-Pan-092124 Papio anubis 95.58 0.00e+00 951.00
IUUC-Psi-093801 Pelodiscus sinensis 94.02 0.00e+00 738.00
IUUC-Pma-094472 Petromyzon marinus 72.37 3.00e-95 340.00
IUUC-Pfo-096330 Poecilia formosa 78.14 0.00e+00 771.00
IUUC-Pab-098191 Pongo abelii 96.15 0.00e+00 957.00
IUUC-Pca-100341 Procavia capensis 94.82 0.00e+00 713.00
IUUC-Pva-103177 Pteropus vampyrus 95.58 0.00e+00 908.00
IUUC-Rno-105048 Rattus norvegicus 93.87 0.00e+00 884.00
IUUC-Sha-107429 Sarcophilus harrisii 94.16 0.00e+00 853.00
IUUC-Sar-113024 Sorex araneus 94.46 0.00e+00 805.00
IUUC-Ssc-115749 Sus scrofa 93.24 1.00e-148 518.00
IUUC-Tgu-117277 Taeniopygia guttata 93.27 0.00e+00 874.00
IUUC-Tru-117844 Takifugu rubripes 78.69 0.00e+00 776.00
IUUC-Tsy-119456 Tarsius syrichta 93.87 0.00e+00 853.00
IUUC-Tni-120251 Tetraodon nigroviridis 74.71 0.00e+00 789.00
IUUC-Tbe-127423 Tupaia belangeri 90.00 0.00e+00 842.00
IUUC-Ttr-128401 Tursiops truncatus 88.75 0.00e+00 775.00
IUUC-Vpa-130549 Vicugna pacos 85.93 2.00e-161 561.00
IUUC-Xtr-131892 Xenopus tropicalis 82.61 0.00e+00 790.00
Created Date 25-Jun-2017

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