iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004124

Ensembl Protein ID

ENSAPLP00000008429.1

UniProt Accession

U3IMF6; U3IMF6_ANAPL

Genbank Protein ID

ENSAPLP00000008429

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01011850

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000008748.1	ENSAPLT00000009108.1	ENSAPLP00000008429.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	66.30	3.00e-124	442.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

QVAPCAVSNV YFFPFPVTMW AGCCNWFCLD GSAEEMQSQP EQGARAQAYS NPGYSSYPSP 60
TASEESCKAC GAHFDNSSRK HICVDCKKHF CMSCSNQTED GPLLCHLCQR FRATGFQREE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTTGCTC CTTGTGCCGT GTCTAATGTA TATTTTTTTC CCTTTCCAGT TACTATGTGG 60
GCAGGCTGTT GTAACTGGTT TTGCCTGGAT GGCTCAGCTG AAGAGATGCA GTCGCAGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	64.93	3.00e-128	451.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	1.00e-08	55.10
IUUC-Ame-011616	Astyanax mexicanus	57.14	1.00e-100	359.00
IUUC-Bta-012374	Bos taurus	64.11	5.00e-127	446.00
IUUC-Cja-019780	Callithrix jacchus	65.30	5.00e-137	480.00
IUUC-Cfa-021252	Canis familiaris	66.03	3.00e-132	464.00
IUUC-Cpo-022047	Cavia porcellus	66.22	3.00e-138	484.00
IUUC-Csa-023161	Chlorocebus sabaeus	65.48	2.00e-138	484.00
IUUC-Cho-024316	Choloepus hoffmanni	65.12	1.00e-107	382.00
IUUC-Dre-028596	Danio rerio	52.62	4.00e-101	360.00
IUUC-Dno-029333	Dasypus novemcinctus	66.58	4.00e-137	480.00
IUUC-Ete-033163	Echinops telfairi	65.56	1.00e-124	438.00
IUUC-Eca-033994	Equus caballus	67.12	5.00e-139	486.00
IUUC-Eeu-035162	Erinaceus europaeus	59.73	4.00e-84	303.00
IUUC-Fca-036418	Felis catus	66.03	9.00e-139	486.00
IUUC-Fal-037427	Ficedula albicollis	79.40	7.00e-159	553.00
IUUC-Gga-041053	Gallus gallus	82.87	1.00e-165	575.00
IUUC-Ggo-045436	Gorilla gorilla	66.30	6.00e-141	493.00
IUUC-Hsa-045798	Homo sapiens	66.30	6.00e-141	493.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	66.12	7.00e-135	473.00
IUUC-Lch-050639	Latimeria chalumnae	57.81	2.00e-114	405.00
IUUC-Laf-053355	Loxodonta africana	64.58	6.00e-131	459.00
IUUC-Mcc-055222	Macaca mulatta	65.75	6.00e-136	476.00
IUUC-Meu-056692	Macropus eugenii	64.38	3.00e-130	457.00
IUUC-Mga-059298	Meleagris gallopavo	79.74	9.00e-166	575.00
IUUC-Mmr-061792	Microcebus murinus	64.56	8.00e-133	466.00
IUUC-Mdo-062986	Monodelphis domestica	65.51	2.00e-137	481.00
IUUC-Mmu-063356	Mus musculus	66.03	1.00e-135	475.00
IUUC-Mpu-066273	Mustela putorius furo	65.48	2.00e-138	484.00
IUUC-Mlu-066953	Myotis lucifugus	66.30	4.00e-135	473.00
IUUC-Nle-070075	Nomascus leucogenys	66.30	3.00e-141	494.00
IUUC-Opr-070838	Ochotona princeps	65.48	6.00e-133	466.00
IUUC-Ont-071967	Oreochromis niloticus	47.67	9.00e-85	306.00
IUUC-Ocu-074807	Oryctolagus cuniculus	66.30	1.00e-138	485.00
IUUC-Ola-086903	Oryzias latipes	70.77	6.00e-50	191.00
IUUC-Oga-088536	Otolemur garnettii	64.56	7.00e-131	459.00
IUUC-Oar-089838	Ovis aries	63.56	9.00e-128	449.00
IUUC-Ptr-090962	Pan troglodytes	66.30	8.00e-141	492.00
IUUC-Pan-092853	Papio anubis	64.93	9.00e-138	482.00
IUUC-Psi-093164	Pelodiscus sinensis	79.83	1.00e-142	498.00
IUUC-Pma-094104	Petromyzon marinus	43.27	2.00e-53	202.00
IUUC-Pno-094968	Phaeosphaeria nodorum	36.73	2.00e-08	55.50
IUUC-Pab-098304	Pongo abelii	66.03	6.00e-140	489.00
IUUC-Pca-100316	Procavia capensis	65.21	2.00e-129	455.00
IUUC-Ppe-101490	Prunus persica	42.37	2.00e-09	57.00
IUUC-Pva-102612	Pteropus vampyrus	55.34	4.00e-102	363.00
IUUC-Rno-105449	Rattus norvegicus	64.66	3.00e-134	471.00
IUUC-Sha-107578	Sarcophilus harrisii	65.70	4.00e-130	457.00
IUUC-Sar-113638	Sorex araneus	64.38	2.00e-126	444.00
IUUC-Ssc-116401	Sus scrofa	65.75	1.00e-137	482.00
IUUC-Tru-118765	Takifugu rubripes	46.72	1.00e-76	279.00
IUUC-Tsy-118850	Tarsius syrichta	62.79	2.00e-106	378.00
IUUC-Tbe-128086	Tupaia belangeri	62.47	3.00e-128	451.00
IUUC-Vpa-130816	Vicugna pacos	70.93	2.00e-31	128.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence