iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059298

UUCD1 version

UUC-MeG-00208

Ensembl Protein ID

ENSMGAP00000004044.2

UniProt Accession

G1MYL0; G1MYL0_MELGA

Protein Name

Uncharacterized protein

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000004256.2	ENSMGAT00000004755.2	ENSMGAP00000004044.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	66.39	2.00e-129	460.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

ACGNEHQADT AALLSVPAGP CGTESLHCSH SFLFTMWASC CNWFCLDGSP EEMQAPQGAR 60
AQAYSNPGYS SFPSPTASEQ SCKACGLHFD SSSRKHICLD CKNNFCTSCS SQPEGGPLLC 120

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Nucleotide Sequence
(Fasta)

GCATGTGGAA ATGAGCACCA GGCTGACACT GCAGCATTGC TGTCAGTGCC TGCAGGGCCG 60
TGTGGCACTG AGAGCCTGCA CTGCTCTCAT TCATTCTTAT GTATGGTTAT AAACAGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	66.30	2.00e-132	464.00
IUUC-Apl-004124	Anas platyrhynchos	79.74	4.00e-155	540.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	2.00e-08	54.70
IUUC-Ame-011616	Astyanax mexicanus	53.83	4.00e-98	350.00
IUUC-Bta-012374	Bos taurus	65.29	4.00e-133	467.00
IUUC-Cja-019780	Callithrix jacchus	66.21	1.00e-134	472.00
IUUC-Cfa-021252	Canis familiaris	66.30	1.00e-131	462.00
IUUC-Cpo-022047	Cavia porcellus	66.85	1.00e-136	479.00
IUUC-Csa-023161	Chlorocebus sabaeus	66.39	7.00e-139	486.00
IUUC-Cho-024316	Choloepus hoffmanni	63.46	4.00e-104	370.00
IUUC-Dre-028596	Danio rerio	53.33	3.00e-105	374.00
IUUC-Dno-029333	Dasypus novemcinctus	66.12	2.00e-135	474.00
IUUC-Ete-033163	Echinops telfairi	68.14	1.00e-128	452.00
IUUC-Eca-033994	Equus caballus	66.85	6.00e-139	486.00
IUUC-Eeu-035162	Erinaceus europaeus	59.73	2.00e-85	308.00
IUUC-Fca-036418	Felis catus	67.12	2.00e-140	491.00
IUUC-Fal-037427	Ficedula albicollis	82.04	5.00e-167	580.00
IUUC-Gga-041053	Gallus gallus	97.50	0.00e+00	684.00
IUUC-Ggo-045436	Gorilla gorilla	66.39	4.00e-140	490.00
IUUC-Hsa-045798	Homo sapiens	66.39	4.00e-140	490.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	66.67	3.00e-133	467.00
IUUC-Lch-050639	Latimeria chalumnae	59.62	3.00e-116	410.00
IUUC-Laf-053355	Loxodonta africana	64.13	2.00e-130	458.00
IUUC-Mcc-055222	Macaca mulatta	65.56	3.00e-134	471.00
IUUC-Meu-056692	Macropus eugenii	64.46	2.00e-132	464.00
IUUC-Mmr-061792	Microcebus murinus	66.57	6.00e-132	463.00
IUUC-Mdo-062986	Monodelphis domestica	68.49	7.00e-142	496.00
IUUC-Mmu-063356	Mus musculus	67.12	3.00e-137	481.00
IUUC-Mpu-066273	Mustela putorius furo	67.40	2.00e-141	494.00
IUUC-Mlu-066953	Myotis lucifugus	67.40	2.00e-139	488.00
IUUC-Nle-070075	Nomascus leucogenys	66.58	2.00e-141	494.00
IUUC-Opr-070838	Ochotona princeps	65.84	2.00e-132	465.00
IUUC-Ont-071967	Oreochromis niloticus	44.88	9.00e-78	283.00
IUUC-Ocu-074807	Oryctolagus cuniculus	66.12	3.00e-138	483.00
IUUC-Obr-076159	Oryza brachyantha	41.07	4.00e-08	50.10
IUUC-Ola-086903	Oryzias latipes	67.63	1.00e-51	196.00
IUUC-Oga-088536	Otolemur garnettii	66.30	4.00e-130	457.00
IUUC-Oar-089838	Ovis aries	64.74	9.00e-131	459.00
IUUC-Ptr-090962	Pan troglodytes	66.39	5.00e-140	489.00
IUUC-Pan-092853	Papio anubis	65.84	5.00e-138	483.00
IUUC-Psi-093164	Pelodiscus sinensis	76.24	1.00e-146	511.00
IUUC-Pma-094104	Petromyzon marinus	44.90	6.00e-58	217.00
IUUC-Pab-098304	Pongo abelii	66.30	5.00e-140	489.00
IUUC-Pca-100316	Procavia capensis	65.29	1.00e-130	459.00
IUUC-Ppe-101490	Prunus persica	45.10	1.00e-08	54.30
IUUC-Pva-102612	Pteropus vampyrus	53.72	1.00e-100	359.00
IUUC-Rno-105449	Rattus norvegicus	68.04	1.00e-136	479.00
IUUC-Sha-107578	Sarcophilus harrisii	68.66	1.00e-131	462.00
IUUC-Sit-110649	Setaria italica	43.40	1.00e-08	52.00
IUUC-Sar-113638	Sorex araneus	66.39	2.00e-130	457.00
IUUC-Ssc-116401	Sus scrofa	67.95	4.00e-143	500.00
IUUC-Tru-118765	Takifugu rubripes	47.18	7.00e-79	286.00
IUUC-Tsy-118850	Tarsius syrichta	61.79	8.00e-103	366.00
IUUC-Tbe-128086	Tupaia belangeri	63.09	6.00e-129	453.00
IUUC-Vpa-130816	Vicugna pacos	73.26	2.00e-32	131.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence