iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074920

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AAGW02062530

Gene Name

KMT2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000011322.3	ENSOCUT00000011348.3	ENSOCUP00000009766.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.00e-28	99.3	888	938

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek.slveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C vCg+ g++ +  l+ C++C +++Hp C+++++++ + ++  w C +C+
   Q: 888  DMCVVCGSFGQGAEgRLLACSQCGQCYHPYCVSIKISKVVLSK-GWRCLECT 938
           79*********9999********************66666665.5******6 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MDGLETTETE NIVETAEIKE QSAEEDAEAE VDNSKQPVTA LQRPMSEESA NSLVSVGVEA 60
KISEQLCAFC YCGEKSSLGQ GDLKQFRVTP GFILPWKNQP SNKKDIDDNS NGACEKIPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTCGAAGT AGAGGAAAAA CTGCAGTGGA AGATGAGGAC AGCATGGATG GACTGGAGAC 60
AACAGAAACA GAAAATATTG TGGAAACAGG TATGAAAACT TAATAAGAAT TTTTAAAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	83.24	0.00e+00	5298.00
IUUC-Apl-003311	Anas platyrhynchos	68.32	0.00e+00	4033.00
IUUC-Aca-004705	Anolis carolinensis	61.54	0.00e+00	3700.00
IUUC-Bta-012322	Bos taurus	79.30	0.00e+00	4896.00
IUUC-Cel-018354	Caenorhabditis elegans	35.38	3.00e-64	241.00
IUUC-Cja-019983	Callithrix jacchus	84.55	0.00e+00	5517.00
IUUC-Cfa-020903	Canis familiaris	81.85	0.00e+00	5350.00
IUUC-Cpo-021732	Cavia porcellus	78.07	0.00e+00	5009.00
IUUC-Csa-023083	Chlorocebus sabaeus	87.61	0.00e+00	7533.00
IUUC-Cho-024469	Choloepus hoffmanni	78.76	0.00e+00	2202.00
IUUC-Dre-028110	Danio rerio	51.87	0.00e+00	1704.00
IUUC-Dor-030569	Dipodomys ordii	76.61	0.00e+00	2917.00
IUUC-Dme-031590	Drosophila melanogaster	34.17	8.00e-71	262.00
IUUC-Eca-033945	Equus caballus	84.26	0.00e+00	5111.00
IUUC-Fca-035922	Felis catus	81.45	0.00e+00	5093.00
IUUC-Gac-041896	Gasterosteus aculeatus	45.91	0.00e+00	1797.00
IUUC-Ggo-044812	Gorilla gorilla	81.68	0.00e+00	5365.00
IUUC-Hsa-046595	Homo sapiens	84.72	0.00e+00	5583.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	82.19	0.00e+00	5194.00
IUUC-Lch-050086	Latimeria chalumnae	56.43	0.00e+00	2564.00
IUUC-Loc-052891	Lepisosteus oculatus	57.47	0.00e+00	3766.00
IUUC-Laf-054348	Loxodonta africana	80.61	0.00e+00	2973.00
IUUC-Mcc-054868	Macaca mulatta	85.30	0.00e+00	5506.00
IUUC-Meu-056322	Macropus eugenii	67.70	0.00e+00	1239.00
IUUC-Mga-059541	Meleagris gallopavo	68.16	0.00e+00	4137.00
IUUC-Mmr-061092	Microcebus murinus	87.53	0.00e+00	7556.00
IUUC-Mdo-062610	Monodelphis domestica	75.85	0.00e+00	2066.00
IUUC-Mmu-063666	Mus musculus	80.38	0.00e+00	5058.00
IUUC-Mpu-066366	Mustela putorius furo	79.47	0.00e+00	4737.00
IUUC-Mlu-068201	Myotis lucifugus	79.55	0.00e+00	4072.00
IUUC-Nle-069232	Nomascus leucogenys	86.76	0.00e+00	7524.00
IUUC-Opr-070625	Ochotona princeps	81.13	0.00e+00	1405.00
IUUC-Ont-072401	Oreochromis niloticus	54.12	0.00e+00	1205.00
IUUC-Oan-072945	Ornithorhynchus anatinus	74.88	0.00e+00	6020.00
IUUC-Ola-086436	Oryzias latipes	45.64	0.00e+00	1335.00
IUUC-Oga-088637	Otolemur garnettii	80.24	0.00e+00	4279.00
IUUC-Oar-089363	Ovis aries	77.88	0.00e+00	4764.00
IUUC-Ptr-091527	Pan troglodytes	84.88	0.00e+00	5618.00
IUUC-Pan-092102	Papio anubis	82.10	0.00e+00	5261.00
IUUC-Pma-094252	Petromyzon marinus	43.25	2.00e-159	557.00
IUUC-Pfo-096288	Poecilia formosa	47.83	0.00e+00	1322.00
IUUC-Pab-098241	Pongo abelii	83.83	0.00e+00	3004.00
IUUC-Pca-100103	Procavia capensis	79.20	0.00e+00	1549.00
IUUC-Pva-102238	Pteropus vampyrus	74.67	0.00e+00	2457.00
IUUC-Rno-105395	Rattus norvegicus	74.26	0.00e+00	1118.00
IUUC-Sha-106550	Sarcophilus harrisii	75.24	0.00e+00	6248.00
IUUC-Sar-113183	Sorex araneus	63.40	0.00e+00	655.00
IUUC-Tgu-116677	Taeniopygia guttata	66.59	0.00e+00	3695.00
IUUC-Tru-118037	Takifugu rubripes	52.48	0.00e+00	1261.00
IUUC-Tsy-118932	Tarsius syrichta	84.02	0.00e+00	3420.00
IUUC-Tni-119970	Tetraodon nigroviridis	47.10	0.00e+00	1377.00
IUUC-Ttr-129051	Tursiops truncatus	79.79	0.00e+00	4951.00
IUUC-Vpa-130236	Vicugna pacos	79.25	0.00e+00	1866.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence