iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097672

Ensembl Protein ID

ENSPPYP00000022954.1

UniProt Accession

H2PW48; H2PW48_PONAB

Genbank Protein ID

ENSPPYP00000022954

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01246978

Gene Name

BRWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000020507.1	ENSPPYT00000023922.1	ENSPPYP00000022954.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-30	104.5	145	182
UBD/Beta-Prp	1.60e-52	178.7	247	507

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll
   Q: 145  GHLSSVYCVAFdrSGRRIFTGSDDCLVKIWATDDGRLL 182
           8**********96669******************9987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheae..vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvl 98
           +++l+++++dgti  w+++ +++        + + s    +  +++ +fs+ g ++ tgs+D++i+++    + ++ +  l+ h+d+v+
   Q: 247  NRYLTSTGADGTICFWQWHVKTMkfrdrpvkFTERSRP--GvqISCSSFSSGGMFITTGSTDHVIRIYylGSEVPEKIAELESHTDKVV 333
           789*************9998777668776433333333..35599***********************887789*************** PP
   S: 99   slsfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
           +++f+ +g   ++vsGs+d t+r+w+ +++++ +                  +++++  v++v+++  +  ++++ ++  +++W++ tg
   Q: 334  AVQFCNNGdsLRFVSGSRDGTARIWQYQQQEWKSIvldmatkmtgnnlpsgEDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITG 422
           ******8832468*******************999************998888888889****************************** PP
   S: 170  kllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           +ll+tl+g h+d v  l+   fd+  + ++s+++dg + +wdl +g+ +r + +         v + +fsp++++++++ s+g + ++
   Q: 423  QLLHTLSG-HDDEVFVLEahpFDQ--RIILSAGHDGNIFIWDLDRGTKIRNYFNMIegqghGAVFDCKFSPDGNHFACTDSHGHLLLF 507
           *******9.*********555555..99********************9888775555556778889999*******99999987765 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAAAPTQIEA ELYYLIARFL QSGPCNKSAQ VLVQELEEHQ LIPRRLDWEG KEHRRSFEDL 60
VAANAHIPPD YLLKICERIG PLLDKEIPQS VPGVQTLLGV GRQSLLRDAK VNITSARQLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCAG CACCTACCCA GATCGAAGCC GGTGGGTAGC TGTGTCGGGG GGTGGGGGGT 60
GCTAAGGGAA TGGGGGCTTA GCGCGAAGGC TGTCAGTTTC TTTTGAAAAA GCTTCTATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	95.01	0.00e+00	3084.00
IUUC-Apl-004016	Anas platyrhynchos	78.28	0.00e+00	2194.00
IUUC-Aca-004722	Anolis carolinensis	78.04	0.00e+00	2216.00
IUUC-Ame-010602	Astyanax mexicanus	72.97	0.00e+00	1068.00
IUUC-Bta-013198	Bos taurus	95.72	0.00e+00	2873.00
IUUC-Bdi-014797	Brachypodium distachyon	30.25	4.00e-58	220.00
IUUC-Cfa-020963	Canis familiaris	94.84	0.00e+00	3059.00
IUUC-Cpo-022448	Cavia porcellus	87.15	0.00e+00	2760.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	35.09	3.00e-33	137.00
IUUC-Csa-023166	Chlorocebus sabaeus	97.41	0.00e+00	3004.00
IUUC-Cin-025553	Ciona intestinalis	39.01	4.00e-112	399.00
IUUC-Dre-028508	Danio rerio	64.53	0.00e+00	1825.00
IUUC-Dno-030070	Dasypus novemcinctus	91.85	0.00e+00	2964.00
IUUC-Dor-031052	Dipodomys ordii	80.00	0.00e+00	1446.00
IUUC-Ete-032650	Echinops telfairi	89.38	0.00e+00	1689.00
IUUC-Eca-033953	Equus caballus	97.12	0.00e+00	2816.00
IUUC-Eeu-034871	Erinaceus europaeus	78.70	0.00e+00	1280.00
IUUC-Fca-036099	Felis catus	94.56	0.00e+00	3090.00
IUUC-Fal-037246	Ficedula albicollis	79.12	0.00e+00	2358.00
IUUC-Gga-041097	Gallus gallus	80.66	0.00e+00	2461.00
IUUC-Gac-042435	Gasterosteus aculeatus	63.77	0.00e+00	1791.00
IUUC-Hsa-045666	Homo sapiens	97.41	0.00e+00	3006.00
IUUC-Loc-051802	Lepisosteus oculatus	68.16	0.00e+00	2004.00
IUUC-Laf-053942	Loxodonta africana	94.22	0.00e+00	2933.00
IUUC-Mcc-054645	Macaca mulatta	97.53	0.00e+00	3009.00
IUUC-Meu-056321	Macropus eugenii	72.43	0.00e+00	1033.00
IUUC-Mga-060063	Meleagris gallopavo	81.21	0.00e+00	2407.00
IUUC-Mmr-061262	Microcebus murinus	94.40	0.00e+00	2911.00
IUUC-Mdo-062320	Monodelphis domestica	73.98	0.00e+00	2224.00
IUUC-Mmu-063163	Mus musculus	92.79	0.00e+00	2978.00
IUUC-Mpu-066628	Mustela putorius furo	94.73	0.00e+00	3070.00
IUUC-Mlu-068082	Myotis lucifugus	94.70	0.00e+00	2908.00
IUUC-Nle-069609	Nomascus leucogenys	97.41	0.00e+00	3024.00
IUUC-Ont-071589	Oreochromis niloticus	64.77	0.00e+00	1783.00
IUUC-Ocu-074122	Oryctolagus cuniculus	94.83	0.00e+00	2137.00
IUUC-Ogu-078641	Oryza glumaepatula	24.73	8.00e-35	143.00
IUUC-Oin-079669	Oryza indica	29.74	1.00e-54	208.00
IUUC-Olo-080755	Oryza longistaminata	29.80	2.00e-55	211.00
IUUC-Ola-086580	Oryzias latipes	64.89	0.00e+00	1832.00
IUUC-Oga-089053	Otolemur garnettii	93.90	0.00e+00	3056.00
IUUC-Oar-090042	Ovis aries	94.56	0.00e+00	3092.00
IUUC-Ptr-091268	Pan troglodytes	96.51	0.00e+00	2957.00
IUUC-Pan-092376	Papio anubis	97.47	0.00e+00	3007.00
IUUC-Psi-093408	Pelodiscus sinensis	79.47	0.00e+00	2461.00
IUUC-Pfo-096515	Poecilia formosa	63.57	0.00e+00	1735.00
IUUC-Pva-102512	Pteropus vampyrus	94.92	0.00e+00	2297.00
IUUC-Rno-105797	Rattus norvegicus	92.28	0.00e+00	2869.00
IUUC-Sha-107061	Sarcophilus harrisii	75.85	0.00e+00	2274.00
IUUC-Sit-110017	Setaria italica	30.19	3.00e-58	221.00
IUUC-Sar-113004	Sorex araneus	84.31	0.00e+00	1667.00
IUUC-Tgu-117254	Taeniopygia guttata	79.97	0.00e+00	2355.00
IUUC-Tru-118186	Takifugu rubripes	64.16	0.00e+00	1811.00
IUUC-Tsy-119003	Tarsius syrichta	88.42	0.00e+00	2691.00
IUUC-Tni-120110	Tetraodon nigroviridis	63.80	0.00e+00	1774.00
IUUC-Tbe-127813	Tupaia belangeri	78.79	0.00e+00	940.00
IUUC-Ttr-129265	Tursiops truncatus	91.08	0.00e+00	2794.00
IUUC-Vpa-130736	Vicugna pacos	90.29	0.00e+00	1503.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence