iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065911

Ensembl Protein ID

ENSMPUP00000019374.1

UniProt Accession

M3Z711; M3Z711_MUSPF

Genbank Protein ID

ENSMPUP00000019374

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01021049

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000019502.1	ENSMPUT00000019654.1	ENSMPUP00000019374.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.10e-12	48.1	28	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 28   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 87
           9*****************************77.......4566677678****************98 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MLDTMEAPGH SRQLLLQLNN QRTKGFLCDV IIVVQNALFR AHKNVLAASS AYLKSLVVHD 60
NLLNLDHDMV SPAVFRLVLD FIYTGRLADG AEAAAAAAVA PGAEPSLGAV LAAASYLQIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGGACA CGATGGAGGC GCCGGGCCAT TCGAGGCAGC TGCTGCTGCA GCTCAACAAC 60
CAGCGCACCA AGGGCTTCTT GTGCGACGTG ATCATCGTGG TGCAGAACGC CCTCTTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	93.10	2.00e-153	535.00
IUUC-Aca-004680	Anolis carolinensis	92.86	4.00e-63	236.00
IUUC-Ame-010967	Astyanax mexicanus	61.47	1.00e-94	340.00
IUUC-Bta-013567	Bos taurus	98.50	1.00e-163	570.00
IUUC-Cja-019621	Callithrix jacchus	98.85	2.00e-42	163.00
IUUC-Cfa-020731	Canis familiaris	98.60	0.00e+00	908.00
IUUC-Cpo-021326	Cavia porcellus	93.42	0.00e+00	863.00
IUUC-Csa-023645	Chlorocebus sabaeus	95.66	0.00e+00	854.00
IUUC-Dre-028027	Danio rerio	58.09	4.00e-91	329.00
IUUC-Dno-028900	Dasypus novemcinctus	93.56	0.00e+00	847.00
IUUC-Fal-036980	Ficedula albicollis	62.56	2.00e-111	396.00
IUUC-Gga-040708	Gallus gallus	59.78	0.00e+00	638.00
IUUC-Ggo-044591	Gorilla gorilla	99.70	1.00e-139	490.00
IUUC-Hsa-046769	Homo sapiens	95.94	0.00e+00	839.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	94.00	0.00e+00	865.00
IUUC-Lch-049412	Latimeria chalumnae	55.25	0.00e+00	629.00
IUUC-Loc-051883	Lepisosteus oculatus	58.46	3.00e-89	322.00
IUUC-Laf-053358	Loxodonta africana	91.54	4.00e-166	578.00
IUUC-Mcc-054981	Macaca mulatta	95.66	0.00e+00	853.00
IUUC-Meu-056181	Macropus eugenii	71.65	3.00e-105	375.00
IUUC-Mga-059592	Meleagris gallopavo	73.20	2.00e-103	369.00
IUUC-Mmr-061560	Microcebus murinus	93.70	0.00e+00	842.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	1.00e-90	327.00
IUUC-Mmu-064258	Mus musculus	94.54	0.00e+00	840.00
IUUC-Mlu-067575	Myotis lucifugus	77.35	1.00e-123	437.00
IUUC-Ont-072493	Oreochromis niloticus	65.97	2.00e-80	293.00
IUUC-Ola-086584	Oryzias latipes	62.42	4.00e-90	325.00
IUUC-Oga-088774	Otolemur garnettii	95.38	0.00e+00	917.00
IUUC-Ptr-090491	Pan troglodytes	96.27	1.00e-125	443.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	59.21	6.00e-88	318.00
IUUC-Pab-098488	Pongo abelii	93.57	5.00e-172	597.00
IUUC-Pca-100667	Procavia capensis	94.92	2.00e-141	496.00
IUUC-Pva-102421	Pteropus vampyrus	94.96	0.00e+00	843.00
IUUC-Rno-105528	Rattus norvegicus	89.64	0.00e+00	802.00
IUUC-Sar-113478	Sorex araneus	99.17	1.00e-119	424.00
IUUC-Ssc-115420	Sus scrofa	94.27	0.00e+00	868.00
IUUC-Tgu-116642	Taeniopygia guttata	59.92	0.00e+00	626.00
IUUC-Tru-118583	Takifugu rubripes	62.34	9.00e-85	308.00
IUUC-Xtr-132210	Xenopus tropicalis	59.28	0.00e+00	657.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence