iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059740

UUCD1 version

UUC-MeG-00316

Ensembl Protein ID

ENSMGAP00000006361.1

UniProt Accession

G1N3P4; G1N3P4_MELGA

Protein Name

Uncharacterized protein

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000006348.1	ENSMGAT00000007110.1	ENSMGAP00000006361.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-41	138.7	241	282
UBD/Beta-Prp	2.40e-54	184.3	195	400

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllks 38
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++s
   Q: 241  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCIQS 282
           8***********9644499********************986 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 195  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCIQ-S 282
           567889999*********99***************************************9778************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ hd+ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 283  FETHDSDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 371
           *******************************************5333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++riW
   Q: 372  HENRVSTLRVSPDGTAFCSGSWDHTLRIW 400
           ***************************** PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MCDQTFLAIV FGPCDKCSNE KPLRAVYIKS EQLSYCSLCV EMTELECALH GPPQSEILLS 60
ALRSLLGAIG AKAFSPSEVL HIVEIVHQVA ERVEALGQFV MKTRRTLKGH GNKVLCMDWC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGACC AGACCTTCTT AGCGATTGTG TTTGGTCCGT GTGACAAGTG CTCCAACGAG 60
AAGCCCCTTA GGGCTGTTTA CATCAAATCA GAACAGCTCA GCTACTGCTC ACTATGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	85.40	0.00e+00	710.00
IUUC-Apl-003399	Anas platyrhynchos	100.00	0.00e+00	653.00
IUUC-Aca-004861	Anolis carolinensis	87.53	0.00e+00	721.00
IUUC-Ame-011851	Astyanax mexicanus	88.73	0.00e+00	642.00
IUUC-Bta-012438	Bos taurus	92.71	0.00e+00	664.00
IUUC-Cel-018408	Caenorhabditis elegans	66.46	1.00e-130	458.00
IUUC-Cja-019086	Callithrix jacchus	87.22	0.00e+00	713.00
IUUC-Cfa-021255	Canis familiaris	86.22	0.00e+00	701.00
IUUC-Cpo-021398	Cavia porcellus	86.82	0.00e+00	711.00
IUUC-Csa-023776	Chlorocebus sabaeus	93.00	0.00e+00	665.00
IUUC-Cin-025305	Ciona intestinalis	62.23	4.00e-124	437.00
IUUC-Csv-026058	Ciona savignyi	61.99	5.00e-123	433.00
IUUC-Dre-028432	Danio rerio	82.29	0.00e+00	676.00
IUUC-Dno-029958	Dasypus novemcinctus	75.68	3.00e-126	443.00
IUUC-Dor-031013	Dipodomys ordii	97.66	1.00e-151	528.00
IUUC-Dme-031889	Drosophila melanogaster	68.47	9.00e-138	482.00
IUUC-Eca-033977	Equus caballus	84.52	0.00e+00	706.00
IUUC-Eeu-035079	Erinaceus europaeus	86.68	0.00e+00	701.00
IUUC-Fca-035693	Felis catus	84.52	0.00e+00	703.00
IUUC-Fal-037345	Ficedula albicollis	91.53	0.00e+00	667.00
IUUC-Gmo-039222	Gadus morhua	93.79	0.00e+00	641.00
IUUC-Gga-040320	Gallus gallus	92.09	0.00e+00	668.00
IUUC-Gac-042644	Gasterosteus aculeatus	87.64	0.00e+00	641.00
IUUC-Ggo-044489	Gorilla gorilla	86.50	0.00e+00	709.00
IUUC-Hsa-046434	Homo sapiens	87.28	0.00e+00	717.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.31	2.00e-175	607.00
IUUC-Loc-052790	Lepisosteus oculatus	86.18	0.00e+00	703.00
IUUC-Laf-054255	Loxodonta africana	86.22	0.00e+00	705.00
IUUC-Mcc-055610	Macaca mulatta	87.97	0.00e+00	715.00
IUUC-Meu-056819	Macropus eugenii	82.66	0.00e+00	665.00
IUUC-Mmr-061221	Microcebus murinus	86.78	0.00e+00	714.00
IUUC-Mdo-062619	Monodelphis domestica	91.81	0.00e+00	668.00
IUUC-Mmu-064266	Mus musculus	86.78	0.00e+00	715.00
IUUC-Mpu-065766	Mustela putorius furo	98.01	3.00e-180	623.00
IUUC-Mlu-067221	Myotis lucifugus	85.07	0.00e+00	704.00
IUUC-Nle-069515	Nomascus leucogenys	97.81	0.00e+00	657.00
IUUC-Opr-070195	Ochotona princeps	79.20	0.00e+00	626.00
IUUC-Ont-071535	Oreochromis niloticus	74.06	3.00e-170	590.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	5.00e-107	379.00
IUUC-Ocu-074666	Oryctolagus cuniculus	98.34	1.00e-180	624.00
IUUC-Ola-086578	Oryzias latipes	94.06	0.00e+00	637.00
IUUC-Oga-089090	Otolemur garnettii	86.35	0.00e+00	709.00
IUUC-Oar-090017	Ovis aries	85.50	0.00e+00	694.00
IUUC-Ptr-091280	Pan troglodytes	84.29	0.00e+00	693.00
IUUC-Pan-092198	Papio anubis	97.81	0.00e+00	657.00
IUUC-Psi-093030	Pelodiscus sinensis	87.32	0.00e+00	728.00
IUUC-Pma-094140	Petromyzon marinus	70.32	4.00e-86	309.00
IUUC-Pfo-097182	Poecilia formosa	94.41	0.00e+00	641.00
IUUC-Pab-098157	Pongo abelii	93.00	0.00e+00	665.00
IUUC-Pca-100988	Procavia capensis	66.33	4.00e-143	500.00
IUUC-Pva-102232	Pteropus vampyrus	98.88	3.00e-160	557.00
IUUC-Rno-105526	Rattus norvegicus	87.36	0.00e+00	627.00
IUUC-Sha-106754	Sarcophilus harrisii	86.78	0.00e+00	706.00
IUUC-Ssc-115390	Sus scrofa	87.31	0.00e+00	714.00
IUUC-Tgu-117377	Taeniopygia guttata	87.97	0.00e+00	709.00
IUUC-Tru-117938	Takifugu rubripes	94.39	0.00e+00	639.00
IUUC-Tsy-119392	Tarsius syrichta	75.56	1.00e-169	588.00
IUUC-Tni-119834	Tetraodon nigroviridis	69.83	6.00e-164	569.00
IUUC-Tbe-127469	Tupaia belangeri	86.39	0.00e+00	656.00
IUUC-Ttr-128252	Tursiops truncatus	84.54	0.00e+00	683.00
IUUC-Vpa-130173	Vicugna pacos	75.15	5.00e-148	516.00
IUUC-Xtr-131803	Xenopus tropicalis	86.53	0.00e+00	712.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence