iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-119663

Ensembl Protein ID

ENSTNIP00000007476.1

UniProt Accession

H3CGU8; H3CGU8_TETNG

Protein Name

Inhibitor of growth protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000000370.1	ENSTNIT00000007635.1	ENSTNIP00000007476.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	9.80e-09	35.5	213	259

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 213  TYC-LCEQVSYGE--MIGCDNdqCPiEWFHFSCVGLT---YKPKGK-WYCPKCR 259
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MLGHQYPNAD KSQQLVSYVE DYLECVESLP LDIQRNVSML REIDAKYQDV LKEVDEVFEK 60
YQGEQDGTQK KRLQTQLQRA LIISQELGDE KIHVVTQMTE LIENCSRQMD SHSLCLQEPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGGGTC ATCAGTATCC AAATGCAGAC AAGTCACAAC AACTGGTCAG CTATGTGGAG 60
GATTATCTGG AATGTGTGGA GTCTCTGCCT TTGGACATAC AAAGAAATGT TTCTATGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011426	Astyanax mexicanus	67.84	2.00e-84	305.00
IUUC-Dre-028562	Danio rerio	68.20	7.00e-93	333.00
IUUC-Gmo-038748	Gadus morhua	72.18	3.00e-97	347.00
IUUC-Gac-041403	Gasterosteus aculeatus	81.85	5.00e-116	409.00
IUUC-Mga-059570	Meleagris gallopavo	66.38	2.00e-62	231.00
IUUC-Ont-071524	Oreochromis niloticus	86.12	3.00e-116	410.00
IUUC-Ola-087400	Oryzias latipes	78.54	1.00e-81	295.00
IUUC-Pfo-096633	Poecilia formosa	81.49	1.00e-105	375.00
IUUC-Tru-118168	Takifugu rubripes	93.50	3.00e-122	430.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence