iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007128

UUCD1 version

UUC-ArT-01634

Ensembl Protein ID

AT1G50490.1

UniProt Accession

Q8L7T3; Q8L8L3; Q9C6Q4; Q9LPS2; UBC20_ARATH

Genbank Protein ID

AAM96887.1; AAY44860.1; AAF87880.1; AAG51188.1; AEE32556.1; BAE99389.1; AAM67229.1; AAO64790.1

Protein Name

Ubiquitin-conjugating enzyme E2 20; E2 ubiquitin-conjugating enzyme 20; Ubiquitin carrier protein 20

Genbank Nucleotide ID

AY127574; DQ027034; AC012561; AC079279; CP002684; AK227382; AY088923; BT005855

Gene Name

UBC20; At1g50490; F11F12.16; F17J6.3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G50490	AT1G50490.1	AT1G50490.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.30e-45	155.4	39	172

Active Site

Position(s)	Description	Evidence
119	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           Rl+ el+ l+    +gisa p+++ +++ w+ +i+G +dt++eg  ++l+++f++dYPfkPPkvkf+t +fhPnv+  G++Cl+il+  +kWs+a++v
   Q: 39   RLQSELMGLMMGGGPGISAFPEED-NIFCWKGTITGSKDTVFEGTEYRLSLSFSNDYPFKPPKVKFETCCFHPNVDVYGNICLDILQ--DKWSSAYDV 133
           89**********************.9************************************************************9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +++llsiqsll epn++spln++aa+l+++++e y+k+v+
   Q: 134  RTILLSIQSLLGEPNISSPLNTQAAQLWSNQEE-YRKMVE 172
           ****************************88776.***996 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MAAVNGYQGN TPADPPASNG SKQPAAPTKT VDSQSVLKRL QSELMGLMMG GGPGISAFPE 60
EDNIFCWKGT ITGSKDTVFE GTEYRLSLSF SNDYPFKPPK VKFETCCFHP NVDVYGNICL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAGCCGTTA GTTAAACGAA ATTCAAAAGC TTCCAAGCGG CGCTTGTTTG CTCTCCAACG 60
TTCACTAACA AATCCGCTTT AAATTTTCCC TTTTCTTTTT TATTCCATTT AAAGTCAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0195--Cyclin
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0008283--P:cell proliferation
GO:0000209--P:protein polyubiquitination
GO:0030071--P:regulation of mitotic metaphase/anaphase transition

KEGG

ath:AT1G50490

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006017	Arabidopsis lyrata	100.00	1.00e-97	347.00
IUUC-Cme-027266	Cyanidioschyzon merolae	53.23	3.00e-36	144.00
IUUC-Eeu-034854	Erinaceus europaeus	64.29	6.00e-35	139.00
IUUC-Fal-037652	Ficedula albicollis	63.92	1.00e-34	136.00
IUUC-Mtr-057687	Medicago truncatula	81.67	1.00e-75	274.00
IUUC-Mga-059929	Meleagris gallopavo	65.56	3.00e-33	132.00
IUUC-Obr-076757	Oryza brachyantha	84.54	7.00e-47	177.00
IUUC-Psi-093206	Pelodiscus sinensis	64.29	9.00e-36	140.00
IUUC-Sce-106133	Saccharomyces cerevisiae	58.06	1.00e-36	144.00
IUUC-Tca-121158	Theobroma cacao	88.89	7.00e-87	311.00
IUUC-Tur-126818	Triticum urartu	81.08	3.00e-52	196.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence