iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035425

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02087142

Gene Name

UBE2E2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000007748.2	ENSFCAT00000002074.3	ENSFCAP00000001916.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.60e-50	168.5	59	194

Active Site

Position(s)	Description	Evidence
139	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel+e++ dpp+++s +p+ + +++ew+ +ilGp++++YeggvF l+i+f++dYPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 59   RIQKELAEITLDPPPNCSHGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 144
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 145  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 194
           *********************************************99985 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MSTEAQRVDD SPSTSGGSSD GDQRESVQQE PEREQVQPKK KEGKISSKTA AKLSTSAKRI 60
QKELAEITLD PPPNCSHGPK GDNIYEWRST ILGPPGSVYE GGVFFLDITF SPDYPFKPPK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCACTG AGGCACAAAG AGTTGATGAC AGTCCAAGCA CTAGTGGAGG AAGTTCTGAT 60
GGAGACCAGC GTGAAAGTGT TCAGCAAGAA CCAGAAAGAG AGCAAGTTCA GCCCAAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0032020--P:ISG15-protein conjugation
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005044	Anolis carolinensis	97.51	6.00e-97	346.00
IUUC-Ame-011419	Astyanax mexicanus	95.10	8.00e-82	295.00
IUUC-Bta-012796	Bos taurus	95.10	7.00e-80	289.00
IUUC-Cre-022791	Chlamydomonas reinhardtii	79.47	5.00e-71	259.00
IUUC-Cho-024986	Choloepus hoffmanni	89.05	5.00e-86	309.00
IUUC-Dre-027376	Danio rerio	97.18	7.00e-82	296.00
IUUC-Dno-029130	Dasypus novemcinctus	99.21	5.00e-74	268.00
IUUC-Dme-032042	Drosophila melanogaster	87.04	1.00e-83	302.00
IUUC-Eca-033312	Equus caballus	97.20	6.00e-83	299.00
IUUC-Eeu-035232	Erinaceus europaeus	97.18	6.00e-82	295.00
IUUC-Fal-037043	Ficedula albicollis	98.01	1.00e-84	305.00
IUUC-Gmo-039645	Gadus morhua	90.64	3.00e-91	327.00
IUUC-Gga-040236	Gallus gallus	99.30	2.00e-84	304.00
IUUC-Gac-041661	Gasterosteus aculeatus	91.04	1.00e-90	325.00
IUUC-Hsa-046767	Homo sapiens	99.50	3.00e-85	307.00
IUUC-Loc-052673	Lepisosteus oculatus	94.03	1.00e-93	335.00
IUUC-Mcc-055072	Macaca mulatta	99.50	3.00e-85	307.00
IUUC-Mga-059436	Meleagris gallopavo	97.20	6.00e-83	299.00
IUUC-Mmr-060629	Microcebus murinus	99.50	3.00e-85	307.00
IUUC-Mdo-063010	Monodelphis domestica	97.20	6.00e-83	299.00
IUUC-Mmu-063733	Mus musculus	99.00	8.00e-99	352.00
IUUC-Mlu-067897	Myotis lucifugus	99.00	3.00e-85	307.00
IUUC-Nle-069421	Nomascus leucogenys	99.50	3.00e-85	307.00
IUUC-Opr-070917	Ochotona princeps	92.98	1.00e-58	217.00
IUUC-Ont-071325	Oreochromis niloticus	91.54	2.00e-91	327.00
IUUC-Oan-073704	Ornithorhynchus anatinus	99.21	6.00e-74	268.00
IUUC-Olu-087783	Ostreococcus lucimarinus	76.43	6.00e-64	235.00
IUUC-Pab-098017	Pongo abelii	99.50	3.00e-85	307.00
IUUC-Pop-099024	Populus trichocarpa	62.94	4.00e-56	209.00
IUUC-Pca-100467	Procavia capensis	97.20	6.00e-83	299.00
IUUC-Pva-102561	Pteropus vampyrus	99.00	3.00e-85	307.00
IUUC-Smo-109298	Selaginella moellendorffii	67.11	1.00e-60	225.00
IUUC-Sar-113672	Sorex araneus	97.20	6.00e-83	299.00
IUUC-Tru-118527	Takifugu rubripes	95.07	8.00e-81	292.00
IUUC-Tsy-119046	Tarsius syrichta	97.20	9.00e-83	299.00
IUUC-Tca-121777	Theobroma cacao	60.42	1.00e-53	202.00
IUUC-Tbe-127690	Tupaia belangeri	97.20	1.00e-82	298.00
IUUC-Ttr-128358	Tursiops truncatus	99.50	3.00e-85	307.00
IUUC-Vpa-130232	Vicugna pacos	97.87	3.00e-80	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence