iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118184

UUCD1 version

UUC-TaR-00401

Ensembl Protein ID

ENSTRUP00000019538.1

UniProt Accession

H2T4F0; H2T4F0_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000007857.1	ENSTRUT00000019617.1	ENSTRUP00000019538.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	4.70e-128	428.0	97	407
E3 adaptor/Cullin RING/DCX/DWD	1.40e-26	92.7	232	267

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+++dfylnLldWss+ vlavaL+++vyl + ++g ++ l++l  e+d+v+s+sw++eg++lavGt++ +v+++Dve++k+
   Q: 97   PDRILDAPEVQNDFYLNLLDWSSHSVLAVALHNCVYLLDTTKGGIISLMKLeCEEDYVCSLSWTKEGSYLAVGTSDCKVQLWDVEHQKR 185
           689***********************************************9789*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....... 170
           vr++++h+arvg+LsWn+++lssGsr+g+i+h+dvrv+e+++ tl++h+qevCGl+w+ d+++LasGGnDn v vw   +         
   Q: 186  VRSMASHTARVGSLSWNDHILSSGSRSGHIHHHDVRVAEHHVCTLTGHSQEVCGLQWSPDGRYLASGGNDNLVCVWPRVQDGglgnrtq 274
           ****************************************************************************9987766777777 PP
   S: 171  PlkkfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslsk 259
            ++k+++h++avka+aw+Pwq+++LasGGG++Dr+i++wn+++g++++++dt+sqv+ ll+++++kelvsthG a+n++++wkypsl+k
   Q: 275  AIHKWSDHQGAVKALAWCPWQHNILASGGGASDRHIRIWNVNSGSCISSLDTQSQVSALLFAPNYKELVSTHGCADNNVVIWKYPSLTK 363
           99*************************************************************************************** PP
   S: 260  vaelkgheaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           v+el+gh+ Rvl+++lspd ++i+t +gDet+ +wk f+ +++k
   Q: 364  VVELHGHDDRVLNASLSPDCSTIATISGDETICLWKSFEVDPVK 407
           **************************************998765 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW.Dlrtg 33
           gH+ +v++l++ +d ++l+sG++D+ + vW ++ +g
   Q: 232  GHSQEVCGLQWsPDgRYLASGGNDNLVCVWpRVQDG 267
           8***********999***************666655 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MGDDRFIPVR NSKQMNVARF LLTKNQPSCT NTYSLSERQK AWSIKLNGYN INNARILQFG 60
GRTLNDPAGC QNNLKVKCGQ TRMPASVQKA RYVSPVPDRI LDAPEVQNDF YLNLLDWSSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAGATG ACCGCTTCAT CCCTGTCAGA AACAGCAAAC AGATGAATGT GGCCAGATTC 60
CTGCTCACAA AGAATCAGCC TTCCTGCACA AATACATATT CATTATCAGT AAGTCAAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	41.61	1.00e-92	333.00
IUUC-Aml-001545	Ailuropoda melanoleuca	59.46	4.00e-137	481.00
IUUC-Apl-003255	Anas platyrhynchos	58.62	3.00e-148	518.00
IUUC-Aca-004920	Anolis carolinensis	57.07	1.00e-141	496.00
IUUC-Aly-006253	Arabidopsis lyrata	43.13	4.00e-95	341.00
IUUC-Ath-006795	Arabidopsis thaliana	42.89	8.00e-95	340.00
IUUC-Bgr-012059	Blumeria graminis	45.62	9.00e-88	317.00
IUUC-Bta-012625	Bos taurus	59.95	4.00e-138	484.00
IUUC-Bci-013607	Botrytis cinerea	46.25	1.00e-89	324.00
IUUC-Bdi-014063	Brachypodium distachyon	41.37	2.00e-94	338.00
IUUC-Bol-015851	Brassica oleracea	43.10	2.00e-94	339.00
IUUC-Bra-016738	Brassica rapa	42.75	9.00e-94	337.00
IUUC-Cja-019132	Callithrix jacchus	59.71	1.00e-138	486.00
IUUC-Cfa-020780	Canis familiaris	59.21	3.00e-137	481.00
IUUC-Cpo-022223	Cavia porcellus	60.20	4.00e-126	444.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	43.66	1.00e-92	333.00
IUUC-Csa-023666	Chlorocebus sabaeus	59.95	1.00e-138	486.00
IUUC-Cho-024920	Choloepus hoffmanni	55.29	9.00e-64	237.00
IUUC-Cin-025675	Ciona intestinalis	48.90	1.00e-98	353.00
IUUC-Csv-026019	Ciona savignyi	48.18	1.00e-95	343.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	44.01	3.00e-89	322.00
IUUC-Cne-026872	Cryptococcus neoformans	44.00	1.00e-84	306.00
IUUC-Dre-028026	Danio rerio	63.57	1.00e-157	549.00
IUUC-Dno-028865	Dasypus novemcinctus	57.74	4.00e-135	474.00
IUUC-Dor-030958	Dipodomys ordii	59.38	4.00e-136	478.00
IUUC-Dse-031391	Dothistroma septosporum	46.63	8.00e-89	321.00
IUUC-Dme-031905	Drosophila melanogaster	45.84	3.00e-110	392.00
IUUC-Ete-032387	Echinops telfairi	53.81	4.00e-127	447.00
IUUC-Eca-033522	Equus caballus	49.52	8.00e-113	400.00
IUUC-Eeu-035059	Erinaceus europaeus	54.19	6.00e-118	417.00
IUUC-Fca-036346	Felis catus	61.19	1.00e-126	446.00
IUUC-Fal-037558	Ficedula albicollis	59.01	9.00e-147	513.00
IUUC-Fox-037850	Fusarium oxysporum	42.62	3.00e-88	318.00
IUUC-Fso-038375	Fusarium solani	43.18	3.00e-89	322.00
IUUC-Gmo-039284	Gadus morhua	69.56	0.00e+00	627.00
IUUC-Ggr-039864	Gaeumannomyces graminis	43.65	5.00e-89	322.00
IUUC-Gga-040790	Gallus gallus	60.49	1.00e-149	522.00
IUUC-Gac-041431	Gasterosteus aculeatus	73.19	1.00e-180	625.00
IUUC-Gma-043985	Glycine max	43.25	3.00e-87	315.00
IUUC-Ggo-045052	Gorilla gorilla	59.71	2.00e-138	486.00
IUUC-Hsa-046305	Homo sapiens	59.71	2.00e-138	486.00
IUUC-Hvu-047476	Hordeum vulgare	41.84	3.00e-94	338.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	59.56	2.00e-125	442.00
IUUC-Lch-050174	Latimeria chalumnae	49.31	5.00e-113	401.00
IUUC-Lpe-050954	Leersia perrieri	42.54	3.00e-85	308.00
IUUC-Loc-052638	Lepisosteus oculatus	61.45	3.00e-143	501.00
IUUC-Lma-052998	Leptosphaeria maculans	42.19	2.00e-87	316.00
IUUC-Laf-053742	Loxodonta africana	59.71	1.00e-137	482.00
IUUC-Mcc-054948	Macaca mulatta	59.95	1.00e-138	486.00
IUUC-Mor-057277	Magnaporthe oryzae	46.93	2.00e-86	313.00
IUUC-Mpo-057624	Magnaporthe poae	43.45	5.00e-87	315.00
IUUC-Mtr-057725	Medicago truncatula	42.26	8.00e-88	317.00
IUUC-Mga-060102	Meleagris gallopavo	60.49	7.00e-150	523.00
IUUC-Mmr-061615	Microcebus murinus	59.47	1.00e-139	489.00
IUUC-Mdo-061982	Monodelphis domestica	61.04	5.00e-121	429.00
IUUC-Mmu-063864	Mus musculus	59.62	9.00e-135	473.00
IUUC-Mpu-066502	Mustela putorius furo	59.26	1.00e-144	506.00
IUUC-Mlu-067277	Myotis lucifugus	56.90	4.00e-133	468.00
IUUC-Ncr-068951	Neurospora crassa	44.08	1.00e-88	320.00
IUUC-Nle-070149	Nomascus leucogenys	59.95	4.00e-137	481.00
IUUC-Opr-070778	Ochotona princeps	59.38	6.00e-90	324.00
IUUC-Ont-071660	Oreochromis niloticus	75.00	0.00e+00	646.00
IUUC-Oan-073677	Ornithorhynchus anatinus	58.40	2.00e-119	422.00
IUUC-Ocu-073797	Oryctolagus cuniculus	60.20	5.00e-139	488.00
IUUC-Ogl-077254	Oryza glaberrima	42.79	9.00e-86	310.00
IUUC-Ogu-078521	Oryza glumaepatula	43.78	1.00e-93	337.00
IUUC-Oni-082540	Oryza nivara	43.28	3.00e-93	335.00
IUUC-Opu-083901	Oryza punctata	43.03	6.00e-92	331.00
IUUC-Oru-084562	Oryza rufipogon	43.78	3.00e-93	336.00
IUUC-Osa-086094	Oryza sativa	41.90	1.00e-85	310.00
IUUC-Ola-086907	Oryzias latipes	77.53	6.00e-178	616.00
IUUC-Oga-088184	Otolemur garnettii	58.44	1.00e-134	473.00
IUUC-Oar-090023	Ovis aries	59.85	6.00e-134	470.00
IUUC-Ptr-090935	Pan troglodytes	59.46	2.00e-137	482.00
IUUC-Pan-091845	Papio anubis	59.95	1.00e-138	486.00
IUUC-Psi-093188	Pelodiscus sinensis	59.11	3.00e-148	518.00
IUUC-Pma-094187	Petromyzon marinus	47.66	4.00e-110	391.00
IUUC-Pno-094809	Phaeosphaeria nodorum	43.70	2.00e-86	313.00
IUUC-Pfo-097429	Poecilia formosa	65.89	2.00e-154	538.00
IUUC-Pab-098603	Pongo abelii	59.95	1.00e-138	486.00
IUUC-Pop-099651	Populus trichocarpa	43.67	1.00e-94	339.00
IUUC-Pca-101062	Procavia capensis	59.71	9.00e-138	483.00
IUUC-Ppe-101865	Prunus persica	44.36	9.00e-86	310.00
IUUC-Pva-102925	Pteropus vampyrus	58.27	1.00e-137	483.00
IUUC-Pte-104142	Pyrenophora teres	41.93	2.00e-87	316.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	41.93	2.00e-87	316.00
IUUC-Rno-106005	Rattus norvegicus	57.81	9.00e-134	470.00
IUUC-Sce-106360	Saccharomyces cerevisiae	39.52	4.00e-70	258.00
IUUC-Sha-107472	Sarcophilus harrisii	59.86	1.00e-137	483.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	40.90	4.00e-86	311.00
IUUC-Spo-108075	Schizosaccharomyces pombe	42.93	3.00e-91	328.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	46.39	3.00e-89	322.00
IUUC-Sit-110732	Setaria italica	43.28	1.00e-92	333.00
IUUC-Sly-111079	Solanum lycopersicum	42.55	3.00e-95	342.00
IUUC-Stu-112676	Solanum tuberosum	42.26	1.00e-87	317.00
IUUC-Sar-113092	Sorex araneus	56.28	4.00e-120	424.00
IUUC-Ssc-115710	Sus scrofa	59.95	8.00e-138	483.00
IUUC-Tgu-117100	Taeniopygia guttata	58.52	3.00e-146	511.00
IUUC-Tsy-118892	Tarsius syrichta	55.77	4.00e-65	241.00
IUUC-Tni-120326	Tetraodon nigroviridis	80.33	0.00e+00	672.00
IUUC-Tca-121337	Theobroma cacao	42.65	5.00e-94	338.00
IUUC-Tre-122211	Trichoderma reesei	42.54	5.00e-87	315.00
IUUC-Tvi-122531	Trichoderma virens	45.00	3.00e-87	315.00
IUUC-Tae-124946	Triticum aestivum	43.84	3.00e-89	322.00
IUUC-Tur-126018	Triticum urartu	43.68	2.00e-89	322.00
IUUC-Tbe-127384	Tupaia belangeri	64.21	5.00e-113	401.00
IUUC-Ttr-128511	Tursiops truncatus	59.85	4.00e-137	481.00
IUUC-Vda-129993	Verticillium dahliae	44.23	2.00e-90	326.00
IUUC-Vpa-130775	Vicugna pacos	42.05	4.00e-67	248.00
IUUC-Vvi-131245	Vitis vinifera	43.42	1.00e-84	306.00
IUUC-Xtr-131993	Xenopus tropicalis	59.76	2.00e-148	518.00
IUUC-Xma-133332	Xiphophorus maculatus	71.96	4.00e-176	610.00
IUUC-Zma-135456	Zea mays	41.13	4.00e-92	331.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence