iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088722

Ensembl Protein ID

ENSOGAP00000009173.2

UniProt Accession

H0X2A2; H0X2A2_OTOGA

Genbank Protein ID

ENSOGAP00000009173

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03125807

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000010245.2	ENSOGAT00000010260.2	ENSOGAP00000009173.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.40e-14	51.0	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d  +++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgQRFASGSADKSVIIW 80
           8***********7779************** PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

QVVVVEWYLQ SNFSIYDLAF KPDGTQLILA AGNKLLVYDT SDGTLVQPLK GHKDTVYCVA 60
YAKDGQRFAS GSADKSVIIW TSKLEGILKY TSWPVKSSLN LHPTFSGLYK TVKVTATNQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAGTTGTGG TAGTTGAATG GTATTTGCAA TCAAATGTAA TTCTTAGCCA TTATTTTTCT 60
CCTTCAAGCA TACTTATTGT TTCATAATGG TAATAAAGTT TGCTTTCCTG GCCATTAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	91.64	0.00e+00	2320.00
IUUC-Apl-003504	Anas platyrhynchos	78.18	0.00e+00	1848.00
IUUC-Aca-004767	Anolis carolinensis	81.24	0.00e+00	2110.00
IUUC-Ame-011642	Astyanax mexicanus	72.95	0.00e+00	1889.00
IUUC-Bta-012969	Bos taurus	88.92	0.00e+00	2227.00
IUUC-Cel-018670	Caenorhabditis elegans	36.62	0.00e+00	865.00
IUUC-Cja-019249	Callithrix jacchus	82.97	0.00e+00	2086.00
IUUC-Cfa-020915	Canis familiaris	91.80	0.00e+00	2274.00
IUUC-Cpo-021888	Cavia porcellus	76.44	0.00e+00	1875.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	46.21	0.00e+00	1112.00
IUUC-Csa-023533	Chlorocebus sabaeus	88.07	0.00e+00	2235.00
IUUC-Cin-025121	Ciona intestinalis	56.37	0.00e+00	1498.00
IUUC-Csv-026240	Ciona savignyi	57.13	0.00e+00	1457.00
IUUC-Dno-029685	Dasypus novemcinctus	85.05	0.00e+00	2132.00
IUUC-Dme-032005	Drosophila melanogaster	26.07	5.00e-09	57.40
IUUC-Ete-032682	Echinops telfairi	84.71	0.00e+00	1677.00
IUUC-Eca-033831	Equus caballus	91.63	0.00e+00	2340.00
IUUC-Eeu-034919	Erinaceus europaeus	86.33	0.00e+00	1016.00
IUUC-Fca-036559	Felis catus	90.32	0.00e+00	2295.00
IUUC-Fal-037340	Ficedula albicollis	77.04	0.00e+00	1969.00
IUUC-Gga-040595	Gallus gallus	77.95	0.00e+00	1819.00
IUUC-Ggo-045356	Gorilla gorilla	89.62	0.00e+00	2289.00
IUUC-Hsa-046135	Homo sapiens	89.47	0.00e+00	2287.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	84.48	0.00e+00	2035.00
IUUC-Lch-050183	Latimeria chalumnae	83.33	0.00e+00	1197.00
IUUC-Loc-052049	Lepisosteus oculatus	76.86	0.00e+00	1990.00
IUUC-Laf-053728	Loxodonta africana	90.48	0.00e+00	2339.00
IUUC-Mcc-054971	Macaca mulatta	89.78	0.00e+00	2290.00
IUUC-Meu-056446	Macropus eugenii	85.02	0.00e+00	2158.00
IUUC-Mga-059296	Meleagris gallopavo	82.28	0.00e+00	2119.00
IUUC-Mmr-061232	Microcebus murinus	93.18	0.00e+00	2355.00
IUUC-Mdo-062115	Monodelphis domestica	89.00	0.00e+00	2276.00
IUUC-Mmu-063664	Mus musculus	88.85	0.00e+00	2321.00
IUUC-Mpu-066136	Mustela putorius furo	87.63	0.00e+00	2239.00
IUUC-Mlu-068238	Myotis lucifugus	86.83	0.00e+00	2234.00
IUUC-Nle-069003	Nomascus leucogenys	84.38	0.00e+00	2119.00
IUUC-Ont-072080	Oreochromis niloticus	73.99	0.00e+00	1954.00
IUUC-Oan-072891	Ornithorhynchus anatinus	75.83	0.00e+00	911.00
IUUC-Ocu-074262	Oryctolagus cuniculus	88.24	0.00e+00	2239.00
IUUC-Ola-086538	Oryzias latipes	71.70	0.00e+00	1861.00
IUUC-Oar-089249	Ovis aries	83.66	0.00e+00	2103.00
IUUC-Ptr-090752	Pan troglodytes	88.15	0.00e+00	2235.00
IUUC-Pan-092472	Papio anubis	88.08	0.00e+00	2240.00
IUUC-Psi-093335	Pelodiscus sinensis	79.95	0.00e+00	2049.00
IUUC-Pma-094520	Petromyzon marinus	71.16	0.00e+00	1489.00
IUUC-Ppa-095600	Physcomitrella patens	42.66	3.00e-29	120.00
IUUC-Pfo-096526	Poecilia formosa	70.44	0.00e+00	1806.00
IUUC-Pab-098428	Pongo abelii	79.24	0.00e+00	1706.00
IUUC-Pca-100233	Procavia capensis	71.27	0.00e+00	983.00
IUUC-Pva-103064	Pteropus vampyrus	82.68	0.00e+00	2016.00
IUUC-Rno-105764	Rattus norvegicus	89.47	0.00e+00	2316.00
IUUC-Sha-106649	Sarcophilus harrisii	89.39	0.00e+00	2297.00
IUUC-Smo-109478	Selaginella moellendorffii	39.29	0.00e+00	732.00
IUUC-Tgu-116870	Taeniopygia guttata	80.11	0.00e+00	2035.00
IUUC-Tru-118661	Takifugu rubripes	70.49	0.00e+00	1829.00
IUUC-Tsy-119640	Tarsius syrichta	76.21	0.00e+00	659.00
IUUC-Tni-120812	Tetraodon nigroviridis	70.50	0.00e+00	1832.00
IUUC-Ttr-128862	Tursiops truncatus	91.19	0.00e+00	2356.00
IUUC-Vpa-130049	Vicugna pacos	86.49	8.00e-158	551.00
IUUC-Xtr-131914	Xenopus tropicalis	76.68	0.00e+00	1981.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence