iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036652

Ensembl Protein ID

ENSFALP00000009092.1

UniProt Accession

U3K238; U3K238_FICAL

Genbank Protein ID

ENSFALP00000009092

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01020393

Gene Name

TRIM8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000008714.1	ENSFALT00000009131.1	ENSFALP00000009092.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.30e-06	27.3	11	80
E3 activity/RING/RING	2.50e-08	34.0	15	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssI.ekwlasggk.tcPvtrqpl.teedlvPnltlrrliqawce 70
           ee++CpI l ++ +Pv lp+ + + r +I e w +++g   cP ++q   ++ +l  nl l ++++++ +
   Q: 11   EELICPICLHVFVEPVQLPCKHNFCRGCIgEAWAKESGLvRCPECNQAYnQKPNLEKNLKLTNIVEKFNS 80
           799**************************77788666668*********666677999999999998865 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl  f + p+ lpC+H f++ C+ ++w     ++s+  rCP C+
   Q: 15   CPICLHVFVE-PVQLPCKHNFCRGCIgEAW----AKESGLVRCPECN 56
           ********99.999****************....88**********7 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MAENWKNCFE EELICPICLH VFVEPVQLPC KHNFCRGCIG EAWAKESGLV RCPECNQAYN 60
QKPNLEKNLK LTNIVEKFNS LNLEKPPSVL HCVFCRRGPP LPGGGGPPLP AQKICLRCEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG 60
GGGGGGGGGT TTTTCCCCCC AGCCCTGCTG GGAAGTGGGA GCAGGTTGAT TTGGGGTGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1900182--P:positive regulation of protein localization to nucleus
GO:0019827--P:stem cell population maintenance

KEGG

fab:101819236

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001258	Ailuropoda melanoleuca	85.00	0.00e+00	991.00
IUUC-Apl-004223	Anas platyrhynchos	98.04	0.00e+00	1087.00
IUUC-Aca-005106	Anolis carolinensis	94.81	0.00e+00	1093.00
IUUC-Ame-011348	Astyanax mexicanus	67.59	0.00e+00	764.00
IUUC-Bta-012787	Bos taurus	84.97	0.00e+00	996.00
IUUC-Cja-019471	Callithrix jacchus	84.44	0.00e+00	989.00
IUUC-Cfa-020052	Canis familiaris	84.97	0.00e+00	995.00
IUUC-Cpo-022491	Cavia porcellus	81.82	0.00e+00	630.00
IUUC-Csa-023544	Chlorocebus sabaeus	84.79	0.00e+00	994.00
IUUC-Dre-028013	Danio rerio	66.49	0.00e+00	755.00
IUUC-Dno-029676	Dasypus novemcinctus	84.79	0.00e+00	996.00
IUUC-Dor-030402	Dipodomys ordii	84.26	0.00e+00	987.00
IUUC-Ete-033188	Echinops telfairi	76.65	0.00e+00	885.00
IUUC-Eca-033524	Equus caballus	84.46	0.00e+00	984.00
IUUC-Eeu-034979	Erinaceus europaeus	80.48	2.00e-119	422.00
IUUC-Fca-036362	Felis catus	84.97	0.00e+00	993.00
IUUC-Gmo-039405	Gadus morhua	59.37	1.00e-179	622.00
IUUC-Gga-040813	Gallus gallus	97.85	0.00e+00	1089.00
IUUC-Gac-041792	Gasterosteus aculeatus	62.35	0.00e+00	633.00
IUUC-Ggo-044962	Gorilla gorilla	84.44	0.00e+00	989.00
IUUC-Hsa-046158	Homo sapiens	84.26	0.00e+00	987.00
IUUC-Itr-048118	Ictidomys tridecemlineatus	84.62	0.00e+00	992.00
IUUC-Lch-049433	Latimeria chalumnae	83.45	0.00e+00	899.00
IUUC-Loc-052026	Lepisosteus oculatus	76.99	0.00e+00	876.00
IUUC-Laf-054159	Loxodonta africana	80.89	0.00e+00	787.00
IUUC-Mcc-055490	Macaca mulatta	84.79	0.00e+00	994.00
IUUC-Meu-056549	Macropus eugenii	85.57	0.00e+00	711.00
IUUC-Mga-059334	Meleagris gallopavo	97.85	0.00e+00	1085.00
IUUC-Mmr-061672	Microcebus murinus	85.15	0.00e+00	998.00
IUUC-Mdo-061849	Monodelphis domestica	84.95	0.00e+00	880.00
IUUC-Mmu-063537	Mus musculus	84.44	0.00e+00	989.00
IUUC-Mpu-065762	Mustela putorius furo	85.15	0.00e+00	998.00
IUUC-Mlu-066979	Myotis lucifugus	80.15	0.00e+00	658.00
IUUC-Nle-069419	Nomascus leucogenys	84.44	0.00e+00	989.00
IUUC-Opr-070981	Ochotona princeps	84.62	0.00e+00	994.00
IUUC-Ont-072053	Oreochromis niloticus	58.08	1.00e-170	592.00
IUUC-Oan-073608	Ornithorhynchus anatinus	92.65	0.00e+00	873.00
IUUC-Ocu-074694	Oryctolagus cuniculus	85.33	0.00e+00	968.00
IUUC-Ola-086949	Oryzias latipes	65.66	9.00e-142	496.00
IUUC-Oga-089175	Otolemur garnettii	84.62	0.00e+00	994.00
IUUC-Oar-089591	Ovis aries	76.01	0.00e+00	799.00
IUUC-Ptr-091309	Pan troglodytes	83.36	0.00e+00	955.00
IUUC-Pan-091903	Papio anubis	84.79	0.00e+00	994.00
IUUC-Psi-093293	Pelodiscus sinensis	93.96	0.00e+00	1048.00
IUUC-Pfo-097191	Poecilia formosa	58.97	1.00e-167	582.00
IUUC-Pab-098251	Pongo abelii	81.04	0.00e+00	939.00
IUUC-Pca-100504	Procavia capensis	84.62	0.00e+00	993.00
IUUC-Pva-102320	Pteropus vampyrus	84.44	0.00e+00	958.00
IUUC-Rno-105545	Rattus norvegicus	84.44	0.00e+00	989.00
IUUC-Ssc-116121	Sus scrofa	84.97	0.00e+00	996.00
IUUC-Tgu-116724	Taeniopygia guttata	98.21	0.00e+00	1087.00
IUUC-Tru-118048	Takifugu rubripes	57.72	6.00e-175	607.00
IUUC-Tni-120856	Tetraodon nigroviridis	58.57	2.00e-168	585.00
IUUC-Tbe-127400	Tupaia belangeri	70.83	3.00e-142	497.00
IUUC-Ttr-128233	Tursiops truncatus	84.08	0.00e+00	972.00
IUUC-Xtr-132578	Xenopus tropicalis	91.41	0.00e+00	1031.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence