iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034430

UUCD1 version

UUC-EqC-00574

Ensembl Protein ID

ENSECAP00000016564.1

UniProt Accession

F6Z824; F6Z824_HORSE

Protein Name

Uncharacterized protein

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018697.1	ENSECAT00000020105.1	ENSECAP00000016488.1
ENSECAG00000018697.1	ENSECAT00000020195.1	ENSECAP00000016564.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.76	0.00e+00	872.00	IUUC-Hsa-045784
E3 activity/RING/RING	27.21	3.00e-28	121.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

ASVLARPQNM VMSFRVSDLQ MLLGFVGRSK SGLKHELVTR ALQLVQFDCS PELFKKIKEL 60
YETRYAKKSS EPVPQPHRPL DPLAMHPTFE RAGAVPRTPL SGPNLDYPVL YGKYLNGLGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCGCGCGT CTGTGCTTGC TCGTCCGCAG AACATGGTCA TGAGCTTCCG AGTCTCCGAC 60
CTGCAGATGC TCCTGGGTTT CGTCGGCCGG AGTAAGAGCG GACTGAAACA CGAACTTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	92.05	0.00e+00	885.00
IUUC-Apl-003765	Anas platyrhynchos	79.45	0.00e+00	810.00
IUUC-Ame-010763	Astyanax mexicanus	60.18	3.00e-144	504.00
IUUC-Bta-012369	Bos taurus	91.99	0.00e+00	892.00
IUUC-Cja-019450	Callithrix jacchus	91.18	0.00e+00	869.00
IUUC-Cfa-020933	Canis familiaris	93.19	0.00e+00	892.00
IUUC-Cpo-022112	Cavia porcellus	90.91	0.00e+00	842.00
IUUC-Csa-023913	Chlorocebus sabaeus	79.38	0.00e+00	704.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	28.32	4.00e-34	139.00
IUUC-Dre-027609	Danio rerio	57.49	5.00e-139	487.00
IUUC-Dno-029664	Dasypus novemcinctus	73.65	1.00e-150	526.00
IUUC-Ete-032988	Echinops telfairi	91.46	6.00e-168	583.00
IUUC-Fca-035968	Felis catus	97.60	5.00e-169	586.00
IUUC-Fal-037449	Ficedula albicollis	82.81	0.00e+00	797.00
IUUC-Fso-038103	Fusarium solani	35.65	6.00e-28	118.00
IUUC-Gmo-038925	Gadus morhua	59.95	3.00e-137	481.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.91	7.00e-31	128.00
IUUC-Gga-040362	Gallus gallus	83.37	0.00e+00	827.00
IUUC-Gac-042353	Gasterosteus aculeatus	58.12	8.00e-131	460.00
IUUC-Ggo-044810	Gorilla gorilla	89.80	0.00e+00	838.00
IUUC-Hsa-045784	Homo sapiens	91.76	0.00e+00	880.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	88.24	0.00e+00	855.00
IUUC-Lch-049727	Latimeria chalumnae	71.43	1.00e-151	529.00
IUUC-Loc-052354	Lepisosteus oculatus	52.74	7.00e-119	420.00
IUUC-Laf-054261	Loxodonta africana	89.69	0.00e+00	876.00
IUUC-Mcc-054931	Macaca mulatta	91.37	0.00e+00	872.00
IUUC-Meu-056468	Macropus eugenii	85.32	0.00e+00	842.00
IUUC-Mor-057185	Magnaporthe oryzae	31.00	5.00e-26	112.00
IUUC-Mpo-057405	Magnaporthe poae	33.61	4.00e-30	125.00
IUUC-Mga-059981	Meleagris gallopavo	88.28	0.00e+00	702.00
IUUC-Mvi-060421	Microbotryum violaceum	29.75	7.00e-28	119.00
IUUC-Mmr-061181	Microcebus murinus	91.83	0.00e+00	843.00
IUUC-Mdo-062345	Monodelphis domestica	84.93	0.00e+00	841.00
IUUC-Mmu-063197	Mus musculus	85.02	0.00e+00	815.00
IUUC-Mpu-066275	Mustela putorius furo	93.28	0.00e+00	887.00
IUUC-Mlu-067194	Myotis lucifugus	90.66	0.00e+00	884.00
IUUC-Ncr-068929	Neurospora crassa	28.04	2.00e-28	120.00
IUUC-Ont-072227	Oreochromis niloticus	58.12	6.00e-136	477.00
IUUC-Ola-086865	Oryzias latipes	60.15	1.00e-134	473.00
IUUC-Oga-088945	Otolemur garnettii	92.94	0.00e+00	889.00
IUUC-Oar-089412	Ovis aries	88.82	0.00e+00	868.00
IUUC-Ptr-091550	Pan troglodytes	84.84	0.00e+00	636.00
IUUC-Pan-092183	Papio anubis	91.18	0.00e+00	877.00
IUUC-Psi-093003	Pelodiscus sinensis	82.87	0.00e+00	815.00
IUUC-Pfo-096704	Poecilia formosa	58.64	3.00e-138	484.00
IUUC-Pab-097923	Pongo abelii	95.79	0.00e+00	749.00
IUUC-Pca-100249	Procavia capensis	76.86	6.00e-141	493.00
IUUC-Pva-102562	Pteropus vampyrus	89.68	0.00e+00	837.00
IUUC-Rno-105762	Rattus norvegicus	85.60	0.00e+00	819.00
IUUC-Sce-106398	Saccharomyces cerevisiae	33.53	4.00e-28	120.00
IUUC-Sha-107253	Sarcophilus harrisii	85.43	0.00e+00	840.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.66	9.00e-31	128.00
IUUC-Sar-113149	Sorex araneus	85.02	1.00e-124	439.00
IUUC-Ssc-115241	Sus scrofa	91.41	0.00e+00	895.00
IUUC-Tgu-116884	Taeniopygia guttata	83.56	0.00e+00	793.00
IUUC-Tru-118031	Takifugu rubripes	58.58	5.00e-142	497.00
IUUC-Tni-119766	Tetraodon nigroviridis	57.91	3.00e-137	481.00
IUUC-Ttr-128556	Tursiops truncatus	83.92	0.00e+00	743.00
IUUC-Xtr-131866	Xenopus tropicalis	75.48	0.00e+00	741.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence