iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118074

UUCD1 version

UUC-TaR-01145

Ensembl Protein ID

ENSTRUP00000041700.1

UniProt Accession

H2UXM1; H2UXM1_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000016307.1	ENSTRUT00000041843.1	ENSTRUP00000041699.1
ENSTRUG00000016307.1	ENSTRUT00000041844.1	ENSTRUP00000041700.1
ENSTRUG00000016307.1	ENSTRUT00000041845.1	ENSTRUP00000041701.1
ENSTRUG00000016307.1	ENSTRUT00000041846.1	ENSTRUP00000041702.1
ENSTRUG00000016307.1	ENSTRUT00000041847.1	ENSTRUP00000041703.1
ENSTRUG00000016307.1	ENSTRUT00000041848.1	ENSTRUP00000041704.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.20e-79	267.8	1489	1858

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.........kkkeklneenp.............kepkgellkslqklfeelwkskk 65
           +GlkN g+tCYmN+v Q+L++ p l+e   +         +         +             ++p++++  ++q+lf +l++sk 
   Q: 1489 VGLKNGGATCYMNAVFQQLYMQPGLAEVRSSpvmntscrpQ---------RgghqaflsieddtDQPEESVFYQVQSLFGHLMESKL 1566
           6**************************99996555554440.........1444455555555589999****************** PP
   S: 66   kavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlks 152
           +++ p++++k++k++++e+   eqqDa Ef++ l+dql+e+l                          kk+  +++ +++Fqg +++
   Q: 1567 QYYVPENFWKIFKMWNRELYVREQQDAYEFFTSLVDQLDEYL--------------------------KKMGREQIFKNTFQGIFSD 1627
           ******************************************..........................789999************* PP
   S: 153  qikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsf 239
           q +c++c ++++ree+f+ l+l v + +     sl+ +L++f++ e leg+n+yycekck+k++++k++ +k+lP vL++hL+Rf f
   Q: 1628 QKICKDCPHRYEREETFMALNLGVTSCQ-----SLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLCIHLMRFGF 1709
           ****************************.....9***************************************************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts.......................peekqkekkkYeLiavvvHsGslssGHYvayvknek 303
           + e ++++k ++++ fp  L+++p+++                        p +k++ +++YeL++vvvHsG+++ GHY++++k+++
   Q: 1710 DWESGRSIKYDEQIRFPWVLNMEPYTVAgmarqdcsgeggegraegssggsPRKKVTISENYELVGVVVHSGQAHAGHYYSFIKDRR 1796
           ***************************9777777777777777777777766666666***************************76 PP
   S: 304  gk....WllfdDskVtevke.eevleetg........................staYvlfYkr 337
           g+    W++f+D+ V+e ++ +e le  +                        ++aY+lfY++
   Q: 1797 GSargrWYKFNDTVVEEFDMnDETLE-YEcfggeyrpkvydqsnpypdvrrryWNAYMLFYQK 1858
           666667************97355555.4459******************************97 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

FPTTNLYELE SRVFTDHWSI PYKREESLGK CLIASTCLAR HGLAEADENC KRFMDRCMPE 60
AFKKLLTSSA VHKWGTEIHE GIYNMLMLLV ELVAERVKQD PVPVNLMGVL TMAFNPDNEY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGACCG AAGAGGAGCA GCACATCACC ACGCTCCTCT GCATGGGCTT CCCTGACCCC 60
GACGTGATAC GGAAAGCGCT CCGTCTGGCT AAGAACGACA TTAACGAGGC TGTGGCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033382--USP24
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002266	Ailuropoda melanoleuca	72.72	0.00e+00	3481.00
IUUC-Apl-003203	Anas platyrhynchos	67.68	0.00e+00	3025.00
IUUC-Aca-004396	Anolis carolinensis	72.11	0.00e+00	3449.00
IUUC-Ame-011886	Astyanax mexicanus	78.65	0.00e+00	1673.00
IUUC-Bta-013381	Bos taurus	72.84	0.00e+00	3472.00
IUUC-Cel-018352	Caenorhabditis elegans	27.68	8.00e-47	184.00
IUUC-Cja-018955	Callithrix jacchus	71.67	0.00e+00	3156.00
IUUC-Cfa-020720	Canis familiaris	72.58	0.00e+00	3476.00
IUUC-Cpo-022430	Cavia porcellus	68.34	0.00e+00	2394.00
IUUC-Csa-024180	Chlorocebus sabaeus	72.38	0.00e+00	3367.00
IUUC-Cho-025074	Choloepus hoffmanni	68.91	0.00e+00	1425.00
IUUC-Dre-027696	Danio rerio	78.05	0.00e+00	3783.00
IUUC-Dno-029307	Dasypus novemcinctus	70.97	0.00e+00	3373.00
IUUC-Dor-030889	Dipodomys ordii	76.85	0.00e+00	2952.00
IUUC-Ete-032294	Echinops telfairi	76.82	0.00e+00	1464.00
IUUC-Eca-033823	Equus caballus	69.79	0.00e+00	3307.00
IUUC-Eeu-035178	Erinaceus europaeus	69.65	0.00e+00	1634.00
IUUC-Fca-035444	Felis catus	72.65	0.00e+00	3461.00
IUUC-Fal-037555	Ficedula albicollis	72.74	0.00e+00	3489.00
IUUC-Gmo-038587	Gadus morhua	81.12	0.00e+00	2451.00
IUUC-Gga-041231	Gallus gallus	72.79	0.00e+00	3500.00
IUUC-Gac-041584	Gasterosteus aculeatus	83.03	0.00e+00	2455.00
IUUC-Ggo-044502	Gorilla gorilla	72.64	0.00e+00	3461.00
IUUC-Hsa-045851	Homo sapiens	72.64	0.00e+00	3460.00
IUUC-Itr-048746	Ictidomys tridecemlineatus	66.92	0.00e+00	1016.00
IUUC-Lch-049999	Latimeria chalumnae	67.63	0.00e+00	3161.00
IUUC-Loc-051767	Lepisosteus oculatus	78.98	0.00e+00	3356.00
IUUC-Laf-054139	Loxodonta africana	72.61	0.00e+00	3459.00
IUUC-Mcc-055217	Macaca mulatta	72.64	0.00e+00	3460.00
IUUC-Meu-056659	Macropus eugenii	64.12	0.00e+00	1385.00
IUUC-Mga-059267	Meleagris gallopavo	72.65	0.00e+00	3503.00
IUUC-Mmr-060971	Microcebus murinus	71.53	0.00e+00	3409.00
IUUC-Mdo-061925	Monodelphis domestica	71.88	0.00e+00	3467.00
IUUC-Mmu-064019	Mus musculus	72.61	0.00e+00	3517.00
IUUC-Mpu-066652	Mustela putorius furo	72.64	0.00e+00	3487.00
IUUC-Mlu-067518	Myotis lucifugus	72.56	0.00e+00	3454.00
IUUC-Nle-069763	Nomascus leucogenys	72.48	0.00e+00	3450.00
IUUC-Opr-071031	Ochotona princeps	70.33	0.00e+00	2140.00
IUUC-Ont-072136	Oreochromis niloticus	83.38	0.00e+00	4013.00
IUUC-Ocu-073880	Oryctolagus cuniculus	71.97	0.00e+00	3467.00
IUUC-Ola-086544	Oryzias latipes	81.73	0.00e+00	3831.00
IUUC-Oga-088695	Otolemur garnettii	72.57	0.00e+00	3480.00
IUUC-Oar-089401	Ovis aries	72.72	0.00e+00	3461.00
IUUC-Ptr-091657	Pan troglodytes	72.64	0.00e+00	3462.00
IUUC-Pan-092394	Papio anubis	72.68	0.00e+00	3462.00
IUUC-Psi-093813	Pelodiscus sinensis	72.44	0.00e+00	3471.00
IUUC-Pma-094698	Petromyzon marinus	48.83	4.00e-120	425.00
IUUC-Pfo-096811	Poecilia formosa	82.92	0.00e+00	3967.00
IUUC-Pab-097814	Pongo abelii	72.64	0.00e+00	3463.00
IUUC-Pca-101135	Procavia capensis	66.10	0.00e+00	1536.00
IUUC-Pva-102334	Pteropus vampyrus	73.40	0.00e+00	3070.00
IUUC-Rno-105040	Rattus norvegicus	72.73	0.00e+00	3482.00
IUUC-Sha-106658	Sarcophilus harrisii	72.07	0.00e+00	3468.00
IUUC-Sar-113153	Sorex araneus	72.37	0.00e+00	1694.00
IUUC-Ssc-115641	Sus scrofa	71.88	0.00e+00	3340.00
IUUC-Tgu-117467	Taeniopygia guttata	69.99	0.00e+00	2434.00
IUUC-Tsy-119165	Tarsius syrichta	77.28	0.00e+00	1738.00
IUUC-Tni-119923	Tetraodon nigroviridis	84.80	0.00e+00	3733.00
IUUC-Tbe-127910	Tupaia belangeri	70.59	0.00e+00	1195.00
IUUC-Ttr-128218	Tursiops truncatus	72.21	0.00e+00	3447.00
IUUC-Vpa-130090	Vicugna pacos	78.02	0.00e+00	1343.00
IUUC-Xtr-131911	Xenopus tropicalis	72.01	0.00e+00	1471.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence